Twenty-five-herb lung disease granules or tablets

A technology for granules and lung diseases, applied in the field of Tibetan medicine, can solve the problems of unstable curative effect, low bioavailability, influence on product promotion, etc., achieves improvement of bioavailability and dissolution rate, simple and easy preparation method, and facilitates drug absorption Effect

Inactive Publication Date: 2017-05-31
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional water pills have the defects of difficult disintegration and unstable curative effect, and its extensive process control process easily leads to unstable product quality and large differences; some drug components are dissolved out, have poor penetration ability, and have low bioavailability, so they cannot be completely The curative effect of the drug is exerted, and the compliance of taking it is poor, which greatly affects the promotion of the product

Method used

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  • Twenty-five-herb lung disease granules or tablets
  • Twenty-five-herb lung disease granules or tablets
  • Twenty-five-herb lung disease granules or tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: Erwuwei Lung Disease Granules

[0026] Weigh 75g of sandalwood, 150g of raspberry, 100g of travertine, 50g of kaempferia, 70g of safflower, 70g of grape, 70g of watercress, 150g of licorice, 70g of rabbit ear grass, 70g of seabuckthorn paste, 70g of pasha ga, and parsley 50g, Bangga 70g, white flower gentian 75g, myrobalan 130g, succulent grass 100g, myrobalan 80g, mustard mustard 50g, emblica 100g, Gansu flea 75g, Tibetan woody fragrance 70g, iron bar hammer (root, leaves) 80g, wide tendon rattan 100g, bezoar 3g, and Ligadu 60g, first crush the bezoar into fine powder, and decoct the remaining medicinal materials with water 10 times the total weight of the medicine for 3 times, each time for 2 hours, and collect them separately . Combine the extract and volatile oil, filter and concentrate the extract at a temperature of 95°C to form a concentrated solution with a relative density of 1.05-1.15, add the volatile oil to the concentrated solution, add bezoar fi...

Embodiment 2

[0027] Embodiment 2: twenty-five flavors lung disease tablet

[0028] Weigh 75g of sandalwood, 150g of raspberry, 100g of travertine, 50g of kaempferia, 70g of safflower, 70g of grape, 70g of watercress, 150g of licorice, 70g of rabbit ear grass, 70g of seabuckthorn paste, 70g of pashaga, and parsley 50g, Bangga 70g, white flower gentian 75g, myrobalan 130g, succulent grass 100g, myrobalan 80g, mustard mustard 50g, emblica 100g, Gansu flea 75g, Tibetan woody fragrance 70g, iron bar hammer (root, leaves) 80g, vine 100g, bezoar 3g, and Ligadu 60g, first crush the bezoar into fine powder, take 60% of the rest of the total amount of medicinal materials, decoct twice with water 15 times the total weight of the drug, and decoct each time Boil for 3 hours, collect and combine the extract and volatile oil separately, filter and concentrate the extract at 85°C to form a concentrated solution with a relative density of 1.05-1.15, add the volatile oil to the concentrated solution to obta...

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Abstract

The invention discloses twenty-five-herb lung disease granules or tablets. The twenty-five-herb lung disease granules or tablets are prepared by removing impurities, cleaning, drying and mixing raw materials such as sandalwood, rubus alceaefolius, travertine, rhizoma kaempferiae, safflower and the like by virtue of a water extraction method or an alcohol extraction method, an obtained concentrated solution, volatile oil and calculus bovis are mixed to prepare active ingredients; and auxiliary materials such as a filling agent, a disintegrating agent, a lubricating agent and an adhesive are added into to the active ingredients to prepare the granules or the tablets by virtue of a conventional traditional Chinese preparation method. Compared with the twenty-five-herb lung disease pills of the prior art, the twenty-five-herb lung disease granules or tablets have the following characteristics: 1, dissolution is rapid, the absorption of drugs is facilitated, and the curative effect is improved; 2, the preparation method is simple and easy, and easy in industrialization; 3, partial herbs are prepared in an extraction and supermicro crushing method or extracted in a water boiling and ethanol refluxing method, so that not only can the active volatile oil ingredient in the herbs be effectively reserved, but also the content of ingredients of crude drugs can be greatly increased, and the bioavailability and the dissolution rate are improved.

Description

technical field [0001] The invention belongs to the field of Tibetan medicine, in particular to a twenty-five flavor lung disease granule or tablet. Background technique [0002] The history of Twenty-Five Flavored Feibing Pills is recorded in the "Sibu Medical Code", the full name "Nanlu Jingyao Eight Branches Secret Knacks Continuation", and it is recorded in the first volume C1-158 of the Ministry of Health's drug standard Tibetan medicine. The prescription of Ershiwuwei Feibing Pills is: 75g of sandalwood, 150g of Rubus, 100g of travertine, 50g of kaempferia, 70g of safflower, 70g of grape, 70g of watercress, 150g of licorice, 70g of rabbit ear grass, 70g of seabuckthorn paste, Xiaga 70g, Parsley celery 50g, Bangga 70g, Gentiana gentiana 75g, Myrobalan 130g, Flesh grass 100g, Myrobalan 80g, Stemless mustard 50g, Amla emblica 100g, Gansu flea 75g, Tibetan woody fragrance 70g , Iron rod hammer (root, leaf) 80g, wide tendon rattan 100g, bezoar 3g, Ligadu 60g. [0003] Pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61K9/16A61K9/20A61P11/00A61P11/14A61P29/00A61K33/10
CPCA61K9/1652A61K9/2059A61K33/10A61K36/185A61K36/23A61K36/28A61K36/286A61K36/31A61K36/36A61K36/47A61K36/484A61K36/51A61K36/515A61K36/59A61K36/66A61K36/714A61K36/73A61K36/80A61K36/87A61K36/898A61K36/906A61K2236/331A61K2236/333A61K2236/51A61K2300/00
Inventor 张婧李翔杨明杨世林钟国跃
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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