Oral dissolution simulation device for tobacco product

Abstract

The invention discloses an oral dissolution simulation device for a tobacco product. The device comprises an artificial saliva bottle, an artificial mouth bottle and a dissolution liquid receiving bottle, wherein the artificial mouth bottle is communicated with the artificial saliva bottle, and is used for extracting a detected matter from the tobacco product to be detected; the dissolution liquid receiving bottle is communicated with the artificial mouth bottle via a liquid taking mechanism, and is used for collecting dissolution liquid of the tobacco product to be detected; and a stirring mechanism for magnetically stirring artificial saliva is arranged at the bottom of the artificial mouth bottle to simulate peristalsis or mastication in the mouth. The dissolution simulation device simulates extraction of the tobacco product in the bottle under the action of saliva, and the obtained dissolution liquid is used for detecting active ingredients such as nicotine and the like later, wherein the stirring mechanism is arranged at the bottom of the artificial mouth bottle, so that the artificial saliva in the artificial mouth contacts the tobacco product to be detected more sufficiently, and peristalsis saliva stirring inside human mouth and further mastication accelerated dissolution are effectively simulated; and the simulation is real, and the problems of inaccurate detection results and the like of such devices can be solved.

Description

technical field [0001] The invention relates to the technical field of component detection equipment, and more specifically, relates to a simulation device for oral cavity dissolution of tobacco products. Background technique [0002] In recent years, buccal-type smokeless tobacco products have gradually become a new hot spot in the cigarette market due to their characteristics of "low tobacco consumption and low harm". However, some scholars have reported that smokeless tobacco products may increase the incidence of leukoplakia in the gums, tongue and around the mouth, while oral cancer and tongue cancer often occur near leukoplakia. Therefore, simulating the oral environment is of great significance for studying the dissolution and toxicological evaluation of tobacco-free products in the oral cavity. [0003] Nicotine is a representative of physiologically active substances in oral smokeless tobacco products. The content of various active substances in tobacco products ha...

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Problems solved by technology

[0006] In view of this, the object of the present invention is to provide a tobacco product oral dissolution simulation device, the structural design of the tobacco product oral dissolution simulation device can effectively solve the technical problems of inaccurate detection results of the existing tobacco product dissolution detection devices, etc.

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