Optical microscope system based on liquid drop and detection method implemented by optical microscope system

Abstract

The invention relates to an optical microscope system based on liquid drop and a detection method implemented by the optical microscope system. The optical microscope system based on the liquid drop comprises an optical microscope, an ultrasonic vibrator, a container, a base plate and an electrode. The electrode is arranged on the base plate, and the base plate is arranged in the container. When the optical microscope system works, a to-be-detected object can be arranged on the electrode, liquid drop materials can be converted into the liquid drop by the ultrasonic vibrator, the liquid drop is suspended in solvents, voltages are applied onto the electrode, and the liquid drop can be shifted to spaces between a lens of the optical microscope and the to-be-detected object by dielectrophoretic force generated after the voltages are applied onto the electrode. The optical microscope system and the detection method have the advantages that the liquid drop is utilized as an optical lens, images of the to-be-detected object can be primarily amplified by the liquid drop, accordingly, influence of external interference and diffraction effects can be lowered, and the resolution can be improved; the liquid drop is suspended in the solvents and can flow along with the solvents; the liquid drop can be shifted by the dielectrophoretic force and can be fixed at specific positions; the resolution of optical microscopic technologies can be improved, and the optical microscope system is simple in structure and low in cost.

Description

technical field [0001] The invention relates to a droplet-based optical microscope system and a detection method thereof, which can be used to observe tiny objects, especially tiny objects such as cells and microorganisms in liquid or gas. Background technique [0002] Optical microscopes are widely used to observe tiny objects. However, due to the effect of optical diffraction, the resolving power of the optical microscope is limited by the wavelength of light; moreover, the objective lens of the optical microscope cannot be close to the object to be measured, which further reduces the resolving power. At present, the resolution of optical microscopes is generally on the order of microns. Observing submicron (or nanometer) objects requires expensive electron microscopes. [0003] Therefore, designing and developing new optical microscopy technology to improve the resolving power of the optical microscope is the motivation of the present invention. Contents of the invent...

AI Technical Summary

Problems solved by technology

However, due to the effect of optical diffraction, the resolving power of the optical microscope is limited by the wavelength of light; moreover, the objective lens of the optical microscope cannot be close to the object to be measured, which further reduces the resolving power

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