Electrowetting-based microfluidic liquid droplet positioning system

A positioning system and electrowetting technology, applied in general control systems, control/regulation systems, fluid controllers, etc., can solve problems such as poor versatility and large dependence on droplet characteristics, achieve direct positioning and control, improve continuous Sex and movement speed, high efficiency effects

Inactive Publication Date: 2017-07-07
SOUTH CHINA NORMAL UNIVERSITY +2
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  • Abstract
  • Description
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  • Application Information

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However, this technology is highly dependent on the ch

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  • Electrowetting-based microfluidic liquid droplet positioning system
  • Electrowetting-based microfluidic liquid droplet positioning system
  • Electrowetting-based microfluidic liquid droplet positioning system

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Embodiment Construction

[0028] It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other.

[0029] Equivalent capacitance is an essential circuit property of EWOD chip. In an EWOD chip with fixed parameters, the capacitance value of each driving electrode unit is only related to the relative position of the droplet and the driving electrode. This scheme utilizes this characteristic to obtain a dimensionless value by collecting the equivalent capacitance ratio on the driving electrodes adjacent to the EWOD chip. According to this dimensionless value, the distribution and position of the droplets on the two driving electrodes can be analyzed and located. From this, its capacitance value can be detected to reflect whether a dead pixel is formed, and the type of dead pixel and the opening ratio of the dead pixel can be judged. The measurement of the capacitance value relies on the capacitance measu...

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Abstract

The invention discloses an electrowetting-based microfluidic liquid droplet positioning system comprising an electrowetting unit, a microprocessor, a master control module, a droplet driver module, a droplet positioning module and a power supply. The method includes: the system uses a to-be-measured droplet in the electrowetting unit and a hydrophobic insulation layer below the droplet as capacitors in series connection; a master control chip sends out a command to the droplet driver module, and the droplet driver module drives the to-be-measured droplet to move; the droplet positioning module collects a current capacitance value of the droplet and determines the relative position of the droplet; and the system checks whether the droplet is at a target position. With the high-intelligence high-precision droplet motion positioning feedback system and method, droplet positioning and controlling can be carried out visually and directly; the operation becomes conveniently; and the efficiency is high. Continuity and motion speed of droplet movement can be improved. The system and method can be applied to the field of the digital microfluidic technology.

Description

technical field [0001] The invention relates to the technical field of digital microfluidics, in particular to a microfluidic droplet positioning system and method based on electrowetting. Background technique [0002] Dielectric wetting microfluidics is a method that uses an electric field to control the surface tension of a liquid. By controlling the applied voltage, the wettability between the droplet and the solid surface is changed, causing a pressure difference inside the droplet, and then driving the movement of the droplet. [0003] Droplet microfluidics, also known as digital microfluidics, has the advantages of less sample consumption, fast response, good mass and heat transfer, and no cross-contamination. It is a research hotspot in microfluidics technology. The classic microfluidic chip mainly operates on continuous fluids. It integrates functional components such as microchannels, micropumps, microvalves, microreservoirs, microelectrodes, detection elements, win...

Claims

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Application Information

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IPC IPC(8): G05B19/042G01N27/22
CPCG05B19/0423G01N27/226G05B2219/25257B01L3/50273B01L3/502792B01L2200/0673B01L2300/0816B01L2300/0645B01L2300/02B01L2400/0427B01L2200/143B01L2200/025B01L2200/027B01L2200/061G05B19/402G05B2219/34215
Inventor 罗智杰路亚旭罗健坤谢淑婷林伟杰周国富
Owner SOUTH CHINA NORMAL UNIVERSITY
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