Antioxidant drug screening kit

A kit and antioxidant technology, applied in the field of biomedicine, can solve the problems of staying and the screening model of nematodes without intellectual property protection, etc., and achieve the effects of simple use method, intuitive and reliable results, and simple and fast operation.
CN106950202BActive Publication Date: 2021-09-28甘肃药业集团科技创新研究院有限公司

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
甘肃药业集团科技创新研究院有限公司
Publication Date
2021-09-28

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Abstract

The invention belongs to the technical field of biomedicine, and in particular relates to an antioxidant drug screening kit and a use method thereof. The antioxidant drug screening kit provided by the present invention includes Caenorhabditis elegans, nematode culture medium, Escherichia coli OP50, 2', 7' dichlorofluorescein ethylene glycol, and can be used for high-throughput screening of antioxidant drugs. The invention is easy to operate and fast in detection, and is suitable for large-scale popularization in the field of screening antioxidant drugs.
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Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and in particular relates to a high-throughput screening kit for antioxidant drugs and a use method thereof. Background technique

[0002] In recent years, with the rapid development of society, the fast-paced living environment makes people extremely vulnerable to oxidative stress damage caused by various stresses, and excessive oxidative stress damage is the cause of premature aging, diabetes and cardiovascular system diseases, etc. Factors that cannot be ignored in severe illness. Therefore, it is imminent to study drugs with low toxicity and significant antioxidant effect.

[0003] At present, the commonly used in vivo animal models for antioxidant drug screening are mainly cells, mice, and rats. Mice and rats are ideal models for testing the efficacy of antioxidant drugs, but their application in the primary screening of a large number of antioxidant drugs is greatly limited by the pro...

Claims

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