Composition for improving immune effect of broiler coccidiosis vaccine and preparing method thereof

Abstract

The invention relates to a composition for improving the immune effect of a broiler coccidiosis vaccine and a preparing method thereof. The composition is prepared from, by weight, 10-40 parts of activated carbon, 10-40 parts of kaolin, 10-20 parts of saccharose, 0.01-0.02 part of sodium chloride and 10-30 parts of nicotinamide. The formula composition is scientific and reasonable, the process is simple, using is convenient, the cost is low, sporulated oocysts in the vaccine can release sporangia rapidly, and sporozoite can enter enterocytes rapidly for schizogenesis and sexual reproduction; meanwhile, damage to epithelial cells in the schizogenesis stage is reduced, damaged intestinal mucosas can be repaired rapidly, more nutrient substances can be absorbed through adsorption, energy required by the body can be replenished in time, the discharge rate of sporulated oocysts in the vaccine in the body of a broiler can be reduced, and the protection rate of the coccidiosis vaccine in the whole broiler flock can be increased.

Description

technical field [0001] The invention belongs to the field of veterinary biological products, in particular to a composition for improving the immune effect of broiler coccidia vaccine and a preparation method thereof. Background technique [0002] Chicken coccidiosis is a global parasitic disease that damages the intestinal tract of poultry. It is one of the most harmful diseases to the breeding industry. It is often explosive. After the occurrence of chicken coccidiosis, it not only affects the production of chickens performance, reduce feed remuneration, cause chick growth retardation, and cause a large number of chickens to die, once the outbreak will cause irreparable economic losses, the incidence rate is as high as 50%-70%, the mortality rate is 20-30%, severe cases As high as 80%, the indirect losses caused by the current application of chemical drug prevention and control are difficult to estimate. For example, drug residues in animal-derived food caused by drugs hav...

AI Technical Summary

Problems solved by technology

[0002] Chicken coccidiosis is a global parasitic disease that damages the intestinal tract of poultry. It is one of the most harmful diseases to the breeding industry. It is often explosive. After the occurrence of chicken coccidiosis, it not only affects the production of chickens performance, reduce feed remuneration, cause chick growth retardation, and cause a large number of chickens to die, once the outbreak will cause irreparable economic losses, the incidence rate is as high as 50%-70%, the mortality rate is 20-30%, severe cases As high as 80%, the indirect losses caused by the current application of chemical drug prevention and control are difficult to estimate. For example, drug residues in animal-derived food caused by drugs have become the biggest barrier for exporting broilers. At the same time, the production of drugs has also brought environmental pollution and other prominent problems to the environment. ; In recent years, some areas of China and major breeding groups have used anti-coccidian vaccines, which are economical and practical, and are beneficial to environmental protection. However, the toxicity of foreign vaccines is too strong for poultry in our country. In China, precocious strains of vaccines are used for immunization, and immune reactions often occur. Insects in the chicken body, affecting feed digestibility, slow weight gain, low protection rate, and a large amount of oocysts