Fast assistant positioning method for disease

Abstract

The invention discloses a fast assistant positioning method for a disease. The method comprises the steps that all phenotypes, described by a patient, of an affected disease are received, and all the received phenotypes are adopted to construct a patient description phenotype set; all diseases with the phenotypes described by the patient in a phenotype annotation database are acquired; phenotypes corresponding to each disease are searched for, and the phenotypes corresponding to each disease are adopted to construct a relevant disease phenotype set; the similarity between the patient description phenotype set and each relevant disease phenotype set is calculated; and the similarities between the patient description phenotype set and all the relevant disease phenotype sets are compared, wherein the higher a similarity value is, the higher the probability of suffering from the disease corresponding to the current similarity by the patient.

Description

technical field [0001] The invention relates to a clinical diagnosis system, in particular to a method for rapidly assisting disease location. Background technique [0002] In the clinical diagnosis of rare diseases, a common problem is how to quickly and accurately analyze the specific disease type of the patient based on the phenotype information of the patient. Phenotype diagnosis is to compare the similarity between the patient's phenotype and the phenotypes of all known disease records. The more similar the disease is to the patient, the more likely it is, so the accurate calculation of the recorded disease phenotype and the phenotype between patients The degree of similarity is the key to successful diagnosis. [0003] Due to various external reasons, such as individual differences in genetics and environment among patients, and differences in the knowledge structure of clinicians, it is impossible for the phenotype description of the patient to be completely consiste...

AI Technical Summary

Problems solved by technology

[0004] In view of the above-mentioned deficiencies in the prior art, the rapid assisted localization method for diseases provided by the present invention solves the problem of inaccurate disease localization caused by incomplete phenotypic data, noise and inaccurate descriptions in actual scenarios

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