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A traditional Chinese medicine composition, powder and preparation method for preventing and treating microsporidia in the intestinal tract of prawns

A technology of microsporidia and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of incompatibility between cost input and profit return, poor growth of shrimp, etc., and achieve the effects of improving autoimmunity, protecting liver and pancreas, and reducing drug stress.

Active Publication Date: 2020-09-01
海一(厦门)水产科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for aquaculture ponds that already suffer from microsporidia in the intestine of prawns, they often face the problem that the growth of prawns is poor, and the cost input is not directly proportional to the profit return.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0047] In the present invention, the preparation method of the traditional Chinese medicine composition includes the following steps:

[0048] A. The Chinese medicine composition obtained by the above scheme is crushed to obtain Chinese medicine powder;

[0049] B. Mixing the traditional Chinese medicine powder obtained in step A with water and extracting to obtain a traditional Chinese medicine extract;

[0050] C. Filter the traditional Chinese medicine extract obtained in step B, and collect the filtrate to obtain a traditional Chinese medicine composition.

[0051] In the present invention, the pulverization method is not particularly limited, and a pulverization method well known to those skilled in the art may be used. The particle size of the crushed Chinese medicine composition is preferably 600-1000 mesh.

[0052] In the present invention, the mass ratio of the traditional Chinese medicine powder to the volume of water is 1 mg: 10-20 ml, more preferably 1 mg: 15 ml.

[0053] In...

Embodiment 1

[0087] Weigh the following Chinese medicines: Sophora flavescens 3g, Astragalus 5g, Jiao malt 5g, Lei Wan 15g, White peony root 5g, Guanzhong 14g, Acorus calamus 2g, Stemona 6g, Turnips 4g, Chenpi 7g, Pueraria lobata 10g, Codonopsis 6g and American ginseng 6g. The above composition was crushed to 800 mesh to obtain traditional Chinese medicine powder; the traditional Chinese medicine powder was mixed with water according to 1mg: 10ml, and extracted at 70°C for 2 hours to obtain the traditional Chinese medicine extract; the extract was filtered, and the filtrate was collected, and the filtrate was hollowed out. Concentrate under the condition of 60°C for 20 minutes to obtain a concentrated paste, which is dried at 65°C to obtain a Chinese medicine composition.

Embodiment 2

[0089] Weigh the following Chinese medicines: Sophora flavescens 5g, Astragalus 2g, Jiao malt 8g, Lei Wan 10g, White peony 8g, Guanzhong 14g, Acorus calamus 2g, Stemona 6g, Turnips 4g, Tangerine peel 7g, Pueraria lobata 10g, Codonopsis 6g and American ginseng 6g. The above composition was crushed to 800 mesh to obtain traditional Chinese medicine powder; the traditional Chinese medicine powder was mixed with water according to 1mg: 10ml, and leached at 80°C for 2 hours to obtain the traditional Chinese medicine extract; the extract was filtered, and the filtrate was collected, and the filtrate was hollowed out. Concentrate at 70°C for 20 minutes in the state to obtain a concentrated paste, which is dried at 65°C to obtain a traditional Chinese medicine composition.

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Abstract

The invention relates to a traditional Chinese pharmaceutical composition for preventing and treating prawn encephalitozoon intestinalis, powder and a preparation method thereof and belongs to the technical field of traditional Chinese medicine. The traditional Chinese pharmaceutical composition is prepared from the following raw materials in parts by weight: 3 to 5 parts of lightyellow sophora root, 2 to 5 parts of radix astragali seu hedysari, 5 to 8 parts of dark malt, 10 to 15 parts of stone-like omphalia, 5 to 8 parts of radix paeoniae alba, 10 to 14 parts of cyrtomium rhizome, 2 to 5 parts of drug sweet flag rhizome, 2 to 6 parts of radix stemonae, 4 to 7 parts of fructus ulmi, 3 to 7 parts of pericarpium citri reticulatae, 10 to 12 parts of radix puerariae, 3 to 6 parts of radix codonopsis and 6 to 8 parts of radix panacis quinquefolii. The powder disclosed by the invention is prepared from the following raw materials of 90% to 95% of the traditional Chinese pharmaceutical composition, 2% to 6% of glucurolactone and 1% to 4% of astaxanthin. The preparation method disclosed by the invention utilizes nanometer low-temperature wall breaking combined with lactobacillus lactis fermentation to improve the release rate of traditional Chinese medicine and keep medicine activity, and finally, the utilization rate is improved by 5 times; meanwhile, compound enzyme is added to perform enzymolysis, so that adhesion of the encephalitozoon intestinalis is effectively reduced, and preventing and treating effects are improved.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition, powder and preparation method for preventing and treating microsporidian in the intestine of shrimp. Background technique [0002] Intestinal epithelial cells, Microsporidia, mainly invade the intestinal epidermis of prawns, and then infect the hepatopancreas, causing the prawns to decrease the intestinal absorption function, severe enteritis and hepatopancreas atrophy. The most obvious feature of prawns infected with Microsporidium in the intestinal epithelial cells is that their growth rate becomes slow, which leads to large individual differences in prawns. However, shrimps infected with microsporidia in intestinal epithelial cells will not die, and their appetite will not be affected and they can eat normally. [0003] At present, no effective measures have been found for the treatment of microsporidia in t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61K9/14A61P33/00A61K31/122A61K31/7048
CPCA61K9/14A61K31/122A61K31/7048A61K36/07A61K36/12A61K36/185A61K36/258A61K36/344A61K36/481A61K36/488A61K36/489A61K36/65A61K36/71A61K36/752A61K36/888A61K36/8998A61K36/904A61K2236/15A61K2236/19A61K2300/00Y02A50/30
Inventor 姜宗然郑杰民卓火龙谭小珺
Owner 海一(厦门)水产科技有限公司
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