Traditional Chinese medicine composition for treating skin inflammation and mucosal repair based on fermentation technology and preparation method thereof

Abstract

The invention relates to a traditional Chinese medicine composition for treating skin inflammation and repairing mucosa on basis of a fermentation technology. The traditional Chinese medicine composition is obtained by performing fermentation preparation on a culture medium containing traditional Chinese medicine materials by microorganism. The traditional Chinese medicine culture medium comprises the following components in parts by weight: 4 to 25 parts of talinum paniculatum, 10 to 30 parts of mesona chinensis, 3 to 10 parts of camphor bark, 2 to 8 parts of maple leave, and 4 to 15 parts of pterocarya stenoptera; the microorganism adopts ganoderma lucidum. The traditional Chinese medicine composition has the efficacies of relieving inflammation and pain, antipyresis, eliminating the swelling, and dispelling acariasis and sore-toxin, and can be applied to the treatment of various skin diseases and mucosal injury.

Description

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating skin inflammation and mucosal repair based on fermentation technology and a preparation method thereof. Background technique

[0002] Covering the surface of the human body, the skin is the largest organ and the first protective barrier of the human body. In addition to protecting the body and resisting external aggression, it also has functions such as sensing stimuli, regulating body temperature, maintaining water and salt metabolism, repairing and excreting waste. With the advancement of society and the improvement of people's living standards, people's living environment and habits have undergone major changes, making human skin vulnerable to various stimuli and pathogenic factors, resulting in allergic reactions or inflammatory symptoms, such as local redness, swelling, Infection, psoriasis, acne, etc., thereby causi...

Examples

Embodiment 1

[0031] Composition of raw materials of traditional Chinese medicine: 15g of native ginseng, 20g of fairy grass, 5g of camphor bark, 2g of maple leaves, and 5g of maple poplar.

[0032] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 80-mesh fine powder, add 19.2g of bran, 9.6g of soybean meal, 0.288g of potassium dihydrogen phosphate, 0.96g of ammonium sulfate, and 0.144g of calcium carbonate g and magnesium sulfate 0.115g, then placed in a fermenter, add water to a water content of 60% by weight, stir evenly, adjust the pH value to 4.2 with vinegar, sterilize at 115°C for 25min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker at a temperature of 25°C and a rotation speed of 100r / min until the content of viable bacteria in the culture medium reached 1.5×10 7 Stop culturing when CFU / ml is reached, and set asi...

Embodiment 2

[0034] Composition of raw materials of traditional Chinese medicine: 18g of native ginseng, 15g of fairy grass, 6g of camphor bark, 3g of maple leaves, and 4g of maple poplar.

[0035] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 80-mesh fine powder, add 7.7g of bran, 15.4g of soybean meal, 0.385g of potassium dihydrogen phosphate, 0.924g of ammonium sulfate, and 0.116g of calcium carbonate g and magnesium sulfate 0.116g, then placed in a fermenter, add water to a water content of 50% by weight, stir evenly, adjust the pH value to 5.0 with vinegar, sterilize at 115°C for 20min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker at a temperature of 20°C and a rotation speed of 120r / min until the content of viable bacteria in the culture medium reached 2.5×10 7 Stop culturing when CFU / ml is reached, and set as...

Embodiment 3

[0037] Composition of traditional Chinese medicine raw materials: 15g of native ginseng, 15g of cayenne grass, 4g of camphor bark, 4g of maple leaves, and 8g of maple poplar.

[0038] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 100-mesh fine powder, add 7.7g of bran, 15.4g of soybean meal, 0.385g of potassium dihydrogen phosphate, 0.924g of ammonium sulfate, and 0.116g of calcium carbonate g and magnesium sulfate 0.116g, then placed in a fermenter, add water to a water content of 70% by weight, stir evenly, adjust the pH value to 4.0 with vinegar, sterilize at 115°C for 30min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker with a temperature of 30°C and a rotation speed of 80r / min until the content of viable bacteria in the culture medium reached 2.5×10 7 Stop culturing when CFU / ml is reached, and set a...

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating skin inflammation and mucosal repair based on fermentation technology and a preparation method thereof. Background technique

[0002] Covering the surface of the human body, the skin is the largest organ and the first protective barrier of the human body. In addition to protecting the body and resisting external aggression, it also has functions such as sensing stimuli, regulating body temperature, maintaining water and salt metabolism, repairing and excreting waste. With the advancement of society and the improvement of people's living standards, people's living environment and habits have undergone major changes, making human skin vulnerable to various stimuli and pathogenic factors, resulting in allergic reactions or inflammatory symptoms, such as local redness, swelling, Infection, psoriasis, acne, etc., thereby causi...

Examples

Embodiment 1

[0031] Composition of raw materials of traditional Chinese medicine: 15g of native ginseng, 20g of fairy grass, 5g of camphor bark, 2g of maple leaves, and 5g of maple poplar.

[0032] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 80-mesh fine powder, add 19.2g of bran, 9.6g of soybean meal, 0.288g of potassium dihydrogen phosphate, 0.96g of ammonium sulfate, and 0.144g of calcium carbonate g and magnesium sulfate 0.115g, then placed in a fermenter, add water to a water content of 60% by weight, stir evenly, adjust the pH value to 4.2 with vinegar, sterilize at 115°C for 25min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker at a temperature of 25°C and a rotation speed of 100r / min until the content of viable bacteria in the culture medium reached 1.5×10 7 Stop culturing when CFU / ml is reached, and set asi...

Embodiment 2

[0034] Composition of raw materials of traditional Chinese medicine: 18g of native ginseng, 15g of fairy grass, 6g of camphor bark, 3g of maple leaves, and 4g of maple poplar.

[0035] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 80-mesh fine powder, add 7.7g of bran, 15.4g of soybean meal, 0.385g of potassium dihydrogen phosphate, 0.924g of ammonium sulfate, and 0.116g of calcium carbonate g and magnesium sulfate 0.116g, then placed in a fermenter, add water to a water content of 50% by weight, stir evenly, adjust the pH value to 5.0 with vinegar, sterilize at 115°C for 20min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker at a temperature of 20°C and a rotation speed of 120r / min until the content of viable bacteria in the culture medium reached 2.5×10 7 Stop culturing when CFU / ml is reached, and set as...

Embodiment 3

[0037] Composition of traditional Chinese medicine raw materials: 15g of native ginseng, 15g of cayenne grass, 4g of camphor bark, 4g of maple leaves, and 8g of maple poplar.

[0038] Preparation method: Grind ginseng, fairy grass, camphor bark, maple leaves and maple poplar into 100-mesh fine powder, add 7.7g of bran, 15.4g of soybean meal, 0.385g of potassium dihydrogen phosphate, 0.924g of ammonium sulfate, and 0.116g of calcium carbonate g and magnesium sulfate 0.116g, then placed in a fermenter, add water to a water content of 70% by weight, stir evenly, adjust the pH value to 4.0 with vinegar, sterilize at 115°C for 30min, cool to room temperature, and set aside; Ganoderma lucidum Bacteria were inoculated into beef extract peptone liquid medium, and cultured on a constant temperature shaker with a temperature of 30°C and a rotation speed of 80r / min until the content of viable bacteria in the culture medium reached 2.5×10 7 Stop culturing when CFU / ml is reached, and set a...

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