Systems and methods for model-based optimization of mechanical ventilation

Abstract

A mechanical ventilator (10) is connected with a ventilated patient (12) to provide ventilation in accordance with ventilator settings of the mechanical ventilator. Physiological values(variables)are acquired for the ventilated patient using physiological sensors (32). A ventilated patient cardiopulmonary (CP) model (40) is fitted to the acquired physiological variables values to generate a fitted ventilated patient CP model by fine-tuning its parameters (50). Updated ventilator settings are determined by adjusting model ventilator settings of the fitted ventilated patient CP model to minimize a cost function (60). The updated ventilator settings may be displayed on a display component (22) as recommended ventilator settings for the ventilated patient, or the ventilator settings of the mechanical ventilator may be automatically changed to the updated ventilator settings so as to automatically control the mechanical ventilator.

Description

technical field [0001] The following relates to the field of respiratory therapy, the field of respiratory monitoring, the field of medical ventilation and related fields. Background technique [0002] Mechanical ventilation (MV) is a common life-saving procedure administered when a patient is unable to obtain adequate ventilation (and thus exchange air) through spontaneous breathing. In passive patient ventilation, the patient cannot assist breathing, and the ventilator operates in a pressure-controlled mode in which the ventilator pressure performs the entire work of breathing. In active patient ventilation, the patient is at least able to assist breathing, and the ventilator operates in a pressure support mode to provide sufficient pressure to overcome any deficiency in the patient's work of breathing (WoB). Volume-controlled modes of ventilator operation are also known, in which flow rate or flow is the controlled parameter, rather than controlling pressure (although pr...

AI Technical Summary

Problems solved by technology

However, these protocols and guidelines are not tuned to a particular user's pathophysiology, and thus may ventilate a patient with suboptimal settings even when the protocols or guidelines are followed correctly

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