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Phospholipid preparations for the improvement of communication skills

A preparation, phospholipid technology, applied in the field of phospholipid preparation, can solve the problems of no report, weight gain, improve oral or non-verbal communication of ASD patients, etc.

Active Publication Date: 2017-10-13
ENZYMOTEC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these medical interventions benefit challenging behaviors, but they have not been reported to improve verbal or non-verbal communication in ASD patients
Additionally, they have significant side effects, including weight gain, sedation, and extrapyramidal effects

Method used

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  • Phospholipid preparations for the improvement of communication skills
  • Phospholipid preparations for the improvement of communication skills
  • Phospholipid preparations for the improvement of communication skills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0117] Embodiment: the effect of preparation of the present invention in autistic patients

[0118] Preparation of Phospholipid Composition: Lipid preparation was prepared as follows: marine lecithin produced by the extraction method of biomass from krill was dissolved in an organic solvent and mixed with L-serine, CaCl2, phospholipase D (PLD) Reacts with aqueous solutions of acetate buffer. After the trans-phosphatidyl transfer reaction, the resulting mixture containing PS, PC, PA and LPA was purified by removal of the aqueous phase, evaporation of the organic solvent and further purification stages. The resulting powder mainly contains EPA, palmitic acid, DHA, oleic acid and linoleic acid bound to different phospholipids.

[0119] Table 1 - List of ingredients in one capsule (167 mg per capsule) containing phospholipid formulation

[0120] parameter

Specification

Phosphatidylserine

n.l.t.75mg / capsule

Phosphatidylcholine

n.l.t.0.0165mg / ca...

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Abstract

The preparation of the present invention was found to be effective for the majority of patients diagnosed with autism. In patients characterized by delayed language development and non- expressive / non-emotional communication patterns, the preparation of the invention was found to be more effective than in patients that were diagnosed with autism without delayed language development and with expressive / emotional communication patterns, even though all patients consumed the preparation for a similar duration. Specific analysis for the type and quality of the improvement detected within the group of patients characterized by delayed language development and non-expressive / non-emotional communication patterns revealed that the majority of patients improved in various communication abilities: speech, language, conversation, and social play.

Description

field of invention [0001] The present invention relates to phospholipid formulations effective in improving the communication ability of subjects suffering from communication impairment / difficulty. Background of the invention [0002] Communication is the sending, receiving or exchanging of ideas, information, signals or messages that enable individuals or groups to persuade, seek information, give information or express emotion. This broad definition includes body language, speaking and writing skills. [0003] Communication impairment / difficulty is a developmental or acquired impairment. The American Speech-Language-Hearing Association (ASHA) more specifically describes communication disorders as affecting a person's ability to "receive, send, process, and comprehend concepts or verbal, non-verbal, and pictorial symbol systems." Communication impairments can partially or completely impede communication. [0004] Communication impairments can include, but are not limited...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/201A61K31/202A61K31/661A61K31/685A61P25/00A23L33/115A23L33/12
CPCA23L33/12A23L33/115A61K31/201A61K31/202A61K31/661A61K31/685A23V2002/00A61K2300/00A23V2200/30A23V2200/322A61P25/00A61P25/18
Inventor 达夫纳·扎勒尔·雷格夫罗伯特·丘德诺瓦雅艾尔·里克特加利·奥尔加·索里亚·阿茨
Owner ENZYMOTEC
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