Use of Bufei Huoxue Capsules in the preparation of medicaments for the treatment of chronic bronchitis

Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to application of a lung-tonifying and blood-activating capsule to the preparation of a drug for treating chronic bronchitis. The lung-tonifying and blood-activating capsule is prepared from a traditional Chinese medicine extract and an auxiliary material according to the ratio of 1:(0.05-0.2); and the traditional Chinese medicine extract is prepared from the following raw materials in part by weight: 50-100 parts of radix astragali, 50-100 parts of radix paeoniae rubra and 25-50 parts of fructus psoraleae. The lung-tonifying and blood-activating capsule provided by the invention can significantly reduce the contents of TNF and ET in chronic bronchitis model rat lung tissues and has a positive therapeutic effect on the chronic bronchitis. In addition, through electric field pretreatment on traditional Chinese medicine fine powder, the load difference of the hard capsule is significantly improved, so that the quality of the hard capsule is greatly improved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to the use of Bufei Huoxue capsules in preparing medicines for treating chronic bronchitis. Background technique [0002] The first part of the 2015 edition of "Chinese Pharmacopoeia" records the prescription of "Bufei Huoxue Hard Capsule", which is composed of 720g of Radix Astragali, 720g of Radix Paeoniae Rubra and 360g of Psoralen. Heart disease (remission period) belongs to Qi deficiency and blood stasis syndrome. Symptoms include coughing and shortness of breath, or coughing, shortness of breath, shortness of breath, cold limbs and weakness, soreness of the waist and knees, cyanotic lips, pale tongue with white fur or dark purple tongue. But there is no report of its role in the treatment of chronic bronchitis. [0003] Chronic bronchitis (Chronic bronchitis for short) is chronic non-specific inflammation of the trachea, bronchial mucosa and...

AI Technical Summary

Problems solved by technology

[0004] In addition, with the continuous development of traditional Chinese medicine technology, the quality requirements of hard capsules in the market are getting higher and higher, and the quality problem of hard capsules that needs to be solved urgently is the difference in the filling capacity of capsules. It is difficult to control the consistency of the weight of each capsule during the processing, so it is difficult to ensure the accuracy of the dosage

For the weight difference problem that hard capsules exist, the prior art records that it is caused by reasons such as the uniformity fluidity of the granules and the management of the process and equipment, and the prior art all tries to improve the process and strengthen the control of the equipment as much as possible. It is possible to reduce the filling difference between hard capsules, but the effect is not ideal

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