Methods and devices for remote ischemic conditioning via partial limb occlusion

An ischemic, limbic technique, used in the field known as "for AMI as well as percutaneous intervention, that addresses the increased risk of thromboembolism, subject pain and discomfort, clot formation, area and duration of avoidance" , Reduced risk of clot formation, Reduced effect of cuff pressure level

Active Publication Date: 2018-01-02
LIFECUFF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] A limitation of the approach described in the '855 patent is that inflating the cuff to such high pressures for an extended period of time may cause pain and discomfort to the subject
In some subjects, prolonged cessation of blood flow may also lead to clot formation and increase the risk of thromboembolism, especially when the limb of choice is a leg rather than an upper arm

Method used

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  • Methods and devices for remote ischemic conditioning via partial limb occlusion
  • Methods and devices for remote ischemic conditioning via partial limb occlusion
  • Methods and devices for remote ischemic conditioning via partial limb occlusion

Examples

Experimental program
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Embodiment Construction

[0042] figure 1 A general view of device 100 including cuff 110 and controller 150 is shown, wherein controller 150 may be (removably or permanently) attached or otherwise operatively connected to cuff 110 . The controller can have an internal microprocessor that can be programmed or otherwise configured to inflate the cuff according to a predetermined delivery regimen for remote ischemic modulation therapy.

[0043] During operation of the controller, the cuff may be inflated or deflated to a certain degree of cuff pressure corresponding to a certain degree of limb occlusion. The instructions cover at least the following different states of cuff inflation and corresponding cuff pressure, listed herein in a general order from low pressure to high pressure:

[0044] a. Full cuff deflation - unrestricted blood flow to the extremity under the cuff, with cuff pressure at or below atmospheric levels;

[0045] b. Cuff retention on the limb - apply a low level of cuff inflation jus...

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Abstract

Single- or dual-bladder devices (100) for automated delivery of remote ischemic conditioning treatment via partial limb occlusion involve various methods of operating the cuff (110) in which partial or full limb occlusion is achieved during the periods of cuff inflation. Achieving clinical benefits of remote ischemic conditioning without extended cessation of limb blood flow are advantageous due to lower required cuff pressure and reduced risk of clot formation in the limb vasculature.

Description

[0001] cross reference data [0002] This patent application is a continuation-in-part of co-pending US Patent Application Serial No. 14 / 305,032 entitled "AUTOMATIC DEVICESFOR REMOTE ISCHEMIC PRECONDITIONING" entitled "AUTOMATIC DEVICESFOR REMOTE ISCHEMIC PRECONDITIONING"; this was filed in 2012 Continuation of U.S. Patent Application No. 13 / 362,039 (now U.S. Patent No. 8,753,283), filed Jan. 31 with the same title; this is again filed on Jun. 22, 2010 and titled "For Remote METHODS AND DEVICESFOR REMOTE ISCHEMIC PRECONDITIONING AND NEAR-CONTINUOUS BLOOD PRESSUREMONITORING" Continuation of US Patent Application Serial No. 12 / 820,273 (now US Patent No. 8,114,026) ; this in turn requires U.S. Provisional Patent Application No. 61 / 219,536, filed June 23, 2009, and entitled "BLOODPRESSURE CUFF INCORPORATING A PRECONDITIONING DEVICE" and filed on October 29, 2009 The benefit of priority in U.S. Provisional Patent Application No. 61 / 256,038, entitled "PRECONDITIONING DEVICES FOR USE ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61H9/00
CPCA61H9/0078A61H2201/1635A61H2201/164A61H2201/165A61H2201/501A61H2201/5033A61H2201/5071A61H2201/5097A61H2230/207A61H2230/25A61H2230/305A61H2230/50A61H9/0092
Inventor 鲍里斯·雷辛斯基
Owner LIFECUFF TECH
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