51results about How to "Reduce risk of formation" patented technology

A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

The invention relates to the field of magnesium alloy of metal materials, and concretely relates to a casting magnesium alloy containing Zn, Al, Cu and Mn with high strength and toughness. The casting magnesium alloy comprises the following components in percentage by weight: 6.0-8.0% of Zn, 0.5-1.5% of Al, 0.5-1.0% of Cu, 0.3-0.7% of Mn and the balance of Mg and inevitable impurity elements, wherein the content of the impurity elements is less than 0.01%. A preparation method of the casting magnesium alloy comprises the steps of: smelting Mg at the temperature of 740-760 DEG C by using an iron crucible; after pure magnesium is completely smelted, sequentially adding preheated pure metal Zn, Al, Cu and Mg-10wt.% and Mg intermediate alloy for alloying, wherein mixed CO2 and SF6 are used as protective gases in the pure magnesium smelting and alloying processes; stirring, slagging off, standing for 15-20 minutes, adjusting the temperature of an alloy fusant to 700-720 DEG C, and casting into an ingot; and carrying out solution treatment on the alloy for 24-64 hours at 350-400 DEG C, quenching by warm water at 40-60 DEG C, then preageing for 8-24 hours at 50-70 DEG C, and finally preageing for 2-6 hours at 150-200 DEG C to obtain the casting magnesium alloy with high strength and toughness. In room temperature extension tests of the casting magnesium alloy, the yield strength is not less than 205MPa, the tensile strength is not less than 305MPa, the elongation rate is not less than 10%, and the casting magnesium alloy has excellent comprehensive mechanical property.

The invention relates to a medicament eluting stent, which consists of a bare stent and a coating coated on the bare stent. The medicament eluting stent is characterized in that the coating at least comprises a polymer layer and a resin layer, wherein the polymer layer comprises polylactic-co-glycolic acid (PLGA) and medicaments; and the resin layer is coated on the surface of the polymer layer. A resin of the invention is coated on the surface of the medicament-loaded polymer coating. Due to the sustained release effect of the resin, on the premise of guaranteeing medicament dosage, the dosage of the polymer is reduced so as to obvious reduce an inflammatory reaction, reduce the generation of adverse reactions such as late intravascular restenosis and the like, and avoid forming late thrombosis.

The invention belongs to the technical field of batteries, and particularly relates to a lithium metal negative plate, a preparation method thereof and a secondary battery. The lithium metal negative electrode plate comprises a negative electrode active layer, the negative electrode active layer comprises a carbon material framework, the carbon material framework has a three-dimensional pore structure, and pores of the three-dimensional pore structure contain a lithium-loving material and metal lithium; the particle size D50 of the lithium-loving material is not higher than 120nm; the particle size D50 of the metal lithium is not higher than 120nm; the porosity of the three-dimensional pore structure is 30%-70%, and the pore diameter is 10-100 m. The lithium metal negative electrode plate provided by the invention comprises the carbon material skeleton with the three-dimensional pore structure, and the pores of the three-dimensional pore structure contain the lithium-loving material and the metal lithium, so that the risk that lithium dendrites are easy to grow on the surface of the lithium metal negative electrode plate is relieved, and meanwhile, the cycling stability and the safety performance of the lithium metal negative electrode plate are improved.

The present invention discloses a valve with anti-thrombosis and anti-calcification functions, and a preparation method and an application of the valve. The valve comprises a valve base and a zwitterionic copolymer covalently connected to the valve base. During preparation, the valve base is firstly soaked in a glutaraldehyde solution to obtain a cross-linked valve; and then the cross-linked valveis soaked in a zwitterionic polymer solution with a concentration of 0.1-5 wt% for reaction for 2-4 days, and then reduction with a reducing agent is conducted to obtain the valve with the anti-thrombosis and anti-calcification functions. The valve material is subjected to anti-thrombosis and anti-calcification treatments, so that after the valve is implanted in patients, risks of valve leaflet thrombosis can be reduced, valve leaflet thickening and transvalvular differential pressure increase are prevented, a long-term hydrodynamic performance is improved, patients can avoid or reduce uses of anticoagulant and antiplatelet drugs, risks of patient bleeding are reduced, besides, aldehyde residues in the valve leaflet tissues are reduced, biocompatibility and anti-calcification ability areimproved, and ultimately complications of valve leaflet thrombosis are reduced and service life of the valve is extended.

The invention relates to a municipal sludge co-treatment method. Municipal sludge and one or more urban organic wastes are subjected to synergistic anaerobic digestion, and various benign complementation can be established between the municipal sludge and the organic wastes and between the organic wastes while the municipal sludge and one or more urban organic wastes are subjected to the synergistic anaerobic digestion; for example, the concentration of heavy metals in the sludge and the concentration of salt in the organic waste can be diluted through co-digestion of municipal sludge and municipal organic waste, the inhibiting effect of toxic substances on anaerobic microorganisms in the anaerobic digestion process is reduced, the concentration of oil in a digestion substrate is reduced,and the risk of oil particle formation is reduced; municipal organic waste and municipal sludge are co-digested, so that nutritional ingredients lacking in respective ingredients can be mutually supplemented, and the carbon-nitrogen ratio of a digestion substrate is adjusted to an appropriate range of anaerobic digestion; compared with single treatment, the urban organic waste and the municipal sludge are co-digested, so that the capital construction and operation cost can be reduced, and better economic benefits are achieved.

The invention discloses an occlusion device for treating intracranial aneurysm or cerebral aneurysm. The occlusion device comprises a mesh, the mesh has an expanded state and a low configuration statefor intravascular delivery to an aneurysm, the mesh includes a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state, wherein (a) the mesh is curved along its width, (b)the mesh is curved along its length, and (c) the mesh has an undulating profile across at least a portion of one or both of its length or its width. The mesh is configured to be placed within the aneurysm in the deployed state such that the mesh extends over a neck of the aneurysm.

The invention provides a biomedical porous Ti-Zn alloy and a preparation method thereof. The preparation method comprises the following steps that S1, titanium powder and zinc powder are mixed according to a certain proportion and then placed in a stainless steel ball milling tank to be subjected to dry mixing; S2, the dry-mixed powder is subjected to mold pressing under the pressure of 500-1000 Mpa to be manufactured into a pressed blank; S3, the pressed blank and the silicon carbide powder are put into a polycrystalline mullite fiber heat preservation barrel and then put into a microwave sintering furnace, argon with the purity being 99.999% is introduced after the vacuum degree in a furnace cavity is pumped to be lower than 0.1 Pa, the output power of the microwave sintering furnace is controlled, microwave sintering is conducted at a certain temperature rising speed, sintering temperature and sintering time, and the biomedical porous Ti-Zn alloy is obtained after furnace cooling. According to the biomedical porous Ti-Zn alloy and the preparation method thereof, the prepared porous Ti-Zn alloy is low in elasticity modulus, excellent in mechanical property and good in antibacterial effect and biological activity, and can be used as a hard tissue repairing and replacing material for bones, joints, artificial tooth roots and the like.

The invention discloses an axial flow blood pump adopting a split through-hole bearing structure. The axial flow blood pump comprises a front cartridge, a rotor, a rotor cartridge and a rear cartridge; three straight blades are uniformly and integrally connected to the annular inner wall of the front cartridge, and the inner walls of the three straight blades are suspended, so that front axial holes are formed; three straight blades are uniformly and integrally connected to the annular inner wall of the rear cartridge, and the inner walls of the three straight blades are suspended, so that rear axial holes are formed; the rotor cartridge is integrally connected between the front cartridge and the rear cartridge; the rotor is arranged in the rotor cartridge; two rotating blades are arranged on the outer circumference of the rotor; and the two rotating blades, which are located between the rear half parts of the rotor, can promote obvious expansion of a runner. The axial flow blood pump provided by the invention has the beneficial effects that since the straight blades in the front cartridge and the rear cartridge, instead of bearings, can take a supporting effect, a rotary-static interface is eliminated; the split bearing structure is defined by the three independent blades; and blood can flow in gaps between front and rear jewel axles and the straight blades, so that a flowing dead zone is prevented and a risk of thrombosis at an axial end is effectively reduced.

The invention relates to an anti-injury medical vessel dilator and simulation method of hemangiectasis. The anti-injury medical vessel dilator comprises a flexible catheter, an injector connector arranged at the inlet end of the flexible catheter and a conical part at the outlet end of the flexible catheter; the injector connector, the flexible catheter and the conical part are connected orderly,the conical part is a hollow conical pipe; diameter of the conical part is gradually enlarged from the free end of the conical part to the joint of the flexible catheter; multiple guide flow holes arearranged on the side wall of the conical part. The invention solves the technical problems that the hemangiectasis section applied to the operation process of autologous internal arteriovenous fistula plasty at present is poor in dilating effect, easy to cause blood vessel injury, and low in operation success rate. The vessel dilator provided by the invention can rapidly dilate operation vessel and not damage blood vessels during the operation process.