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A kind of antifreeze cracking paste and preparation method thereof

A technology for anti-freeze cracking and preparation steps, which is applied in the directions of ointment delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. Inflammatory effect, good anti-inflammatory and anti-tumor activity, and the effect of improving anti-allergic effect

Active Publication Date: 2020-07-28
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This invention can't effectively play the effect of anti-freezing and cracking, and the cold resistance stability is not good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0028] Prepare antifreeze cracking cream according to the ratio (in parts by weight) of Table 1:

[0029] Example 1 Example 2 Example 3 Example 4 Artemisia essential oil 1 3 2 2.5 Lemon Peel Essential Oil 3 2 4 5 Ceteareth-25 7.5 10.5 9 12 Mannose Erythritol Ester 2.5 3.5 3 4 Deionized water 18 25 20 15 White Vaseline 15 16 18 20 suet 10 9 8 5 Sorbic acid 1 0.5 0.8 0.9 Propylene Glycol 2.5 2 3 4

[0030] Table 1

[0031] The preparation method of embodiment 1-4 comprises the following steps:

[0032] (1) Dry and crush the wormwood leaves to 50 mesh to obtain wormwood leaf powder. Add the wormwood leaf powder to ultrapure water at a solid-to-liquid ratio of 1:18g / mL, soak for 4 hours, install a fractionation device, and heat the water to the reflux temperature. Extract by steam distillation for 3 hours, and dehydrate the obtained extract with anhydrous sodium sulfate to obtain...

Embodiment 2

[0039] Lemon peel essential oil is not included in the components, and other components and preparation methods are the same as in Example 3.

Embodiment 3

[0041] Mannose erythritol ester is not included in the components, and other components and preparation methods are the same as in Example 3.

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PUM

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Abstract

The invention provides a frost crack prevention cream. The frost crack prevention cream is prepared from, by weight, 1-3 parts of Artemisia argyi essential oil, 2-5 parts of lime peel essential oil, 10-16 parts of an emulsifier, 15-25 parts of water, 15-20 parts of Vaseline, 5-10 parts of animal oil, 0.5-1 part of a preservative and 2-4 parts of a humectant. The invention also provides a preparation method of the frost crack prevention cream. The frost crack prevention cream has very good frost crack prevention, swelling elimination, inflammation prevention and allergy prevention effects and has very good cold proofing stability.

Description

technical field [0001] The invention relates to an antifreeze cracking paste and a preparation method thereof. Background technique [0002] Both chilblain and chapped skin are physical skin diseases. Chilblain usually occurs on exposed parts such as fingers, toes, ears, and nose. Under the influence of low temperature and cold, purple spots, edema, and inflammation appear. , is prone to frequently-occurring disease in winter cold season, and takes a turn for the better with warm season, but is easy to recur in winter. Chapped refers to the fissures of different depths and lengths that occur on the skin of fingers, toes, palms, heels, etc. It is a skin disease caused by dry skin and linear fissures caused by various reasons. The incidence of skin diseases is more common in autumn and winter. [0003] Chinese patent application CN201710165265.0 discloses frozen cracked nano-emulsion, which belongs to the technical field of preparation and production of modern traditional Ch...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K9/06A61P17/02A61K31/7024
Inventor 王一飞任哲利奕成黄焕荣
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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