Application of reduced glutathione in preparation of diabetic foot treatment ointment

Abstract

The invention discloses application of reduced glutathione in preparation of a diabetic foot treatment ointment. The diabetic foot treatment ointment for external use refers to a clathrate compound prepared from reduced glutathione and cyclodextrin. According to the application, the conventional treatment methods utilizing reduced glutathione are changed by the applying treatment way; the ointmentis convenient to use; as proved by tests, the ointment functions at the affected part effectively, has excellent treatment effect to ulcers and infections caused by the diabetic foot, expands application and treatment field of reduced glutathione, and provides an innovative practical application way for current medical treatment means, and its application has great significance.

Description

technical field [0001] The invention relates to the preparation of medicines for treating diabetic feet, in particular to the application of reduced glutathione in the preparation of medicaments for treating diabetic feet. Background technique [0002] Diabetic patients with neuropathy and various degrees of peripheral vascular disease can cause damage and deformity of the soft tissue and bone joint system of the foot, leading to diabetic foot, and serious ulcers and infections. 15% of diabetic patients may have foot problems, and 85% of amputations are due to foot ulcers. [0003] At present, the main way to treat diabetic foot ulcers and infections is surgical debridement, which is very traumatic. The therapeutic effect of reduced glutathione (GSH) on diabetes is also limited to the treatment of diabetic neuropathy, diabetic nephropathy, diabetic fatty liver and other complications. The main reason is that the current reduced glutathione dosage forms such as intravenous ...

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