A precise control method for radiotherapy equipment during adaptive radiotherapy for eye tumors

A radiation therapy and self-adaptive technology, applied in radiation therapy, X-ray/γ-ray/particle irradiation therapy, treatment, etc., can solve the problem of ocular tumors deviating from the planned position, achieve good social and economic benefits, and improve Effects on quality of life and reduction of complications

Active Publication Date: 2020-01-24
THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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Problems solved by technology

[0003] However, due to whether the human eyeball has voluntary movement or not, the position of the eye tumor is also changing all the time, and the radiotherapy plan is designed based on the CT scan at a certain time. At this moment, the positions of the eyeball and the eye tumor are different is fixed, which causes the position of the eye tumor to deviate from the planned position during the actual treatment

Method used

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Embodiment Construction

[0036] The present invention can be better described below in conjunction with specific embodiments.

[0037] A gating method for an accelerator during adaptive radiation therapy for eye tumors, comprising the following steps:

[0038] (1) Conduct CT scan of the eye, and at the same time use OCT to continuously collect eye movement, obtain the displacement parameters caused by eye movement within a certain period of time, and obtain the location of the eye tumor through OCT and CT image registration, and Collect EOG signal caused by eye movement;

[0039](2) The amplitude threshold method is used to identify the collected EOG signal, and the differential method is used to link and normalize the collected EOG signal and the eye movement collected by OCT. Through time-weighted analysis, the displacement parameter is taken as the coordinate, and the Time is the abscissa, and the movement frequency signal map of the eye tumor is obtained within a certain period of time, and the a...

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Abstract

The invention relates to a precise control method of a radio-therapeutic apparatus during adaptive radiotherapy of an ocular tumor. An accelerator is gated during adaptive radiotherapy of the ocular tumor; when the position of the ocular tumor is deviated from a planned position, operation of the accelerator is stopped, and damage of radio-therapeutic rays on normal ocular cells is prevented; andwhen the position of the ocular tumor returns to the planned position, operation of the accelerator is recovered, and precise radiotherapy of the ocular tumor is realized. During radiotherapy of the ocular tumor, automatic tracking adaption of a multi-leaf collimator is realized, the multi-leaf collimator can track and adjust the position in real time according to the real-time position of the ocular tumor, and precise adaptive radiotherapy of the ocular tumor is realized. A gated therapeutic system of the ocular tumor and the automatic tracking system of the multi-leaf collimator can be designed and used for precise positioning radiotherapy of the ocular tumor, the social and economical benefit is high, complication of radiotherapy is reduced, and the life quality of patients is improved.

Description

technical field [0001] The invention relates to a precise control method of radiotherapy equipment during adaptive radiotherapy for eye tumors. Background technique [0002] Radiation therapy is one of the important methods for eye tumors, especially for tumors such as choroidal melanoma, retinal glioma, pediatric rhabdomyosarcoma, intraocular lymphoma and uveal melanoma. Give the tumor target area a large enough radiation dose through precise external beam radiation technology, and avoid damage to surrounding normal tissues (optic nerves, spots, ciliary body and crystal) through a steep dose gradient around the tumor, improving the tumor target area. Precise radiation can effectively protect the eyesight of patients with eye tumors and the normal function of the eyeball. [0003] However, due to whether the human eyeball has voluntary movement or not, the position of the eye tumor is also changing all the time, and the radiotherapy plan is designed based on the CT scan at ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B3/00
CPCA61N5/1017A61N5/1048A61N5/1049A61N5/1071A61N5/1077A61N5/1078A61N2005/1061A61N2005/1092A61N2005/1096
Inventor 金献测谢聪颖沈梅晓
Owner THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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