Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them

Abstract

This application provides compositions, e.g., formulations, used for gastric, gastrointestinal and / or colonic treatments, and methods for making, storing and using them, including storage, including long term storage, at ambient temperature. Compositions provided herein are useful for treating various diseases or conditions such as autism spectrum disordor, Crohn's Disease, ulcerative colitis, irritable bowel syndrome, and recurrent or primary C.difficile infection.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of priority to US Provisional Patent Application No. 62 / 161,826, filed May 14, 2015, which is hereby incorporated by reference in its entirety. technical field [0003] The present invention relates generally to medicine as well as gastroenterology, pharmacology and microbiology. In alternative embodiments, there is provided for gastric, gastrointestinal and / or colonic therapy or lavage, e.g., orthostatic lavage, e.g., for inducing decontamination (e.g. cleansing) of the gastrointestinal (GI) tract including the colon Compositions, such as formulations; and methods for making, storing and using them, including storage, including long-term storage. In alternative embodiments, the compositions provided herein are used for stabilizing, ameliorating, treating and / or preventing constipation, for treating abdominal pain, especially non-specific abdominal pain; and diarrhea, including side e...

AI Technical Summary

Problems solved by technology

However, the use of such treatments is limited by the logistics of obtaining fresh FMT material from pre-screened donors in a timely fashion

Images