Test method of electrochemical sensor

Abstract

The invention relates to the technical field of electrochemical detection, and especially relates to a test method of an electrochemical sensor. The test method can be used to accurately judge whethersample introduction is correct or not during the detection of a sample to be tested by adopting the electrochemical sensor, can significantly reduce a deviation between a detection value and a real value, allows the measured value to be accurate and reliable, and effectively solves the problem of inaccurate detection of existing detection methods.

Description

technical field [0001] The invention relates to the technical field of electrochemical detection, in particular to a testing method for an electrochemical sensor. Background technique [0002] Electrochemical sensors (test strips) have been used to detect or measure the presence of a certain substance in a fluid sample, or the concentration level of the substance, and the test results are used as a health reference or a basis for disease diagnosis. An electrochemical sensor includes a reagent mixture comprising at least one electron transfer agent (also referred to as an "electron mediator") and an analyte-specific biocatalytic protein (eg, a particular enzyme) and one or more electrodes. Such sensors rely on the transfer of electrons between the electronic mediator and the electrode surface and function by measuring electrochemical redox reactions. In an electrochemical biosensor system or device, an electrical signal related to the concentration of the analyte being measu...

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Problems solved by technology

[0003] In the existing electrochemical sensor testing methods, due to the different sample injection methods, individual electrodes may not be able to fully absorb the sample due to different sample injection directions, or the electrodes cannot be fully absorbed due to insufficient sample dosage and spread of the sample surface. Filling, or due to multiple intermittent injections, the electrodes cannot be detected or the detected signals are inaccurate, such as three-electrode electronic sensors, due to different injection methods, different doses, reasons for the sample itself, and certain differences in the electronic components of the instrument The characteristics or the detection of environmental temperature and other factors cause the two working electrodes to undergo chemical reactions one after another, and the current value generated by the chemical reaction is first large and then small

For the current signal detected in this way, I1 is relatively small because the first reaction current tends to be stable, and I2 is still at a relatively high level because the rear reaction current is still at a relatively high level, so the magnitudes of the two detected current signals are different. Among them, the corresponding calculation of I1 The concentration is relatively close to the real concentration, but the calculated concentration corresponding to I2 has a large deviation from the real concentration, which eventually leads to a large deviation between the detected concentration and the real concentration, which affects the accuracy of the test result

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