Method for rapid detection of multi-class pharmaceutical and personal care products and pesticides in water

Abstract

The invention provides a method for rapid detection of multi-class pharmaceutical and personal care products and pesticides in water. The method includes: taking a to-be-detected water sample, and subjecting the to-be-detected water sample to pretreatment to obtain a to-be-detected sample; employing one or more groups of the following five groups of detection conditions for liquid chromatography-tandem mass spectrometry detection on the to-be-detected sample respectively so as to realize qualitative analysis and quantitative detection of multi-class pharmaceutical and personal care products and pesticides in the to-be-detected water sample: (a) the mobile phase is a formic acid-ammonium formate aqueous solution and acetonitrile, and the ionization mode is electrospray ionization positive mode; (b) the flow phase is a formic acid aqueous solution and acetonitrile, and the ionization mode is electrospray ionization positive mode; (c) the mobile phase is an acetic acid-ammonium acetate aqueous solution and acetonitrile, and the ionization mode is electrospray ionization negative mode; (d) the mobile phase is water and acetonitrile, and the ionization mode is electrospray ionization negative mode; and (e) the mobile phase is a formic acid-ammonium formate solution and acetonitrile, and the ionization mode is electrospray ionization positive mode.

Description

technical field [0001] The invention relates to the technical field of environmental monitoring, in particular to a method for rapidly detecting multi-category medicines, personal care products and pesticides in water. Background technique [0002] Pharmaceuticals and personal care products (PPCPs) include various prescription and non-prescription drugs (such as antibiotics, anti-inflammatory drugs, sedatives, lipid-lowering drugs and anti-epileptic drugs, etc.) Agents, mosquito repellents and disinfectants, etc.), which can be divided into sulfonamides, quinolones, tetracyclines, macrolides and hormones according to their chemical categories. As an emerging pollutant, PPCPs have been proven to be potentially harmful to human health and the ecological environment. At present, PPCPs have become a research hotspot in the field of water environment. [0003] As one of the important material inputs in agricultural production activities, pesticides are mainly used to control pes...

AI Technical Summary

Problems solved by technology

At present, although many pretreatment methods and analytical techniques have been developed to assess the pollution of PPCPs and pesticides in water, most of the analytical methods are only applicable to PPCPs or pesticides, and the scope of application is limited to PPCPs and pesticides. a certain class of

[0005] To sum up, the existing analysis methods for PPCPs and pesticides in water have the disadvantages of single detection types, long analysis time and high analysis cost.

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