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Method and system for non-invasive functional assessment of coronary artery stenosis

A non-invasive, coronary artery technology, applied in image data processing, instrumentation, medical simulation, etc.

Active Publication Date: 2018-07-20
SIEMENS HEALTHCARE GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pressure wire-based FFR measurements involve risks associated with interventions that require insertion of a pressure wire into the vessel, and for very narrow stenosis, a pressure wire can induce an additional pressure drop

Method used

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  • Method and system for non-invasive functional assessment of coronary artery stenosis
  • Method and system for non-invasive functional assessment of coronary artery stenosis
  • Method and system for non-invasive functional assessment of coronary artery stenosis

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Embodiment Construction

[0015] The present invention relates to methods and systems for non-invasive functional assessment of coronary artery stenosis using medical image data and blood flow simulation. Embodiments of the invention are described herein to give a visual understanding of methods for simulating blood flow and assessing coronary artery stenosis. Digital images often consist of digital representations of one or more objects (or shapes). Digital representations of objects are often described herein in terms of recognizing and manipulating objects. Such manipulations are virtual manipulations implemented in memory or other circuitry / hardware of a computer system. Accordingly, it should be understood that embodiments of the present invention may be implemented within a computer system using data stored within the computer system.

[0016] figure 1 A framework for non-invasive functional assessment of coronary artery stenosis according to an embodiment of the invention is illustrated. as ...

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Abstract

A method and system for non-invasive assessment of coronary artery stenosis is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient acquired during rest state. Patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Patient-specific rest state boundary conditions of the model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Hyperemic blood flow and pressure across at least one stenosisregion of the coronary arteries are simulated using the model of coronary circulation and the patient-specific hyperemic boundary conditions. Fractional flow reserve (FFR) is calculated for the at least one stenosis region based on the simulated hyperemic blood flow and pressure.

Description

[0001] This case is a divisional application with application number: 201310090217.1 and title of invention: method and system for non-invasive functional assessment of coronary artery stenosis. This application claims priority to US Provisional Application No. 61 / 610,134, filed March 13, 2012, the disclosure of which is incorporated herein by reference. technical field [0002] The present invention relates to non-invasive functional assessment of coronary artery stenosis, and more particularly, to non-invasive functional assessment of coronary artery stenosis from medical image data and blood flow simulation. Background technique [0003] Cardiovascular disease (CVD) is the leading cause of death worldwide. Among the various CVDs, coronary artery disease (CAD) accounts for almost fifty percent of those deaths. Despite dramatic improvements in medical imaging and other diagnostic modalities, the increase in premature morbidity and mortality in CAD patients remains very hig...

Claims

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Application Information

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IPC IPC(8): A61B5/02A61B5/026G16H50/50G06T7/11
Inventor P.沙马L.M.伊图A.卡门B.乔治斯库郑旭东H.德D.科马尼丘D.贝恩哈德特F.贝加-希盖拉M.朔伊尔林
Owner SIEMENS HEALTHCARE GMBH
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