Compound medroxyprogesterone composition for pets and application

Abstract

The invention relates to a compound anti-fertility composition for pets and application, belonging to the field of veterinary medicines. The composition is prepared from the following effective ingredients of medroxyprogesterone and lithospermum erythrorhizon as a Chinese herb extract and can be further prepared from one or multiple Chinese herb extracts with an anti-fertility effect, and the composition is prepared from the following components in parts by weight: 1-150,000 parts of medroxyprogesterone and 1-100,000 parts of a lithospermum erythrorhizon extract. The pharmaceutical compositionprovided by the invention can be a suspension, an intramuscular injection mode is adopted to administrate and the pharmaceutical composition is convenient and easy to perform. The mode of combining Chinese traditional medicine with Western medicine is adopted by the composition for the first time, the lithospermum erythrorhizon extract and the medroxyprogesterone are reasonable in compatibility of medicines to form a compound for synergistic interaction so as to realize multi-target point, multi-link and multi-level anti-fertility effects, the contraception rate can be effectively improved, the untoward effects are reduced, the effect is remarkable, the curative effect is definite, the safety is high, the preparation method is simple, the operation is convenient, and the composition is suitable for industrialized production and is supposed to be popularized and applied more in clinic treatment.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a compound medroxyprogesterone acetate composition preparation for combined treatment with traditional Chinese and western medicine and its application in anti-fertility treatment for pets. Background technique [0002] With the rapid development of China's economy and society, more and more people choose to keep pets to accompany their lives. China has had the habit of keeping cats and dogs since ancient times. According to official reports, the number of pet dogs in China has reached more than 150 million, which is equivalent to one pet dog for every nine Chinese. There are an average of 100,000 dogs in each city, and the number is increasing by 10,000 every year. Nowadays, the problem of overbreeding of pet dogs in domestic cities has become a major concern of the society. According to calculations, if a pair of healthy pet cats mate without any contro...

AI Technical Summary

Problems solved by technology

But at the same time, there are also some limitations. Due to the mild and slow effect of Chinese herbal medicine, the effective contraceptive rate of pets cannot be fully guaranteed, and the bioavailability of Chinese herbal medicine is low, and the treatment cycle is long. Therefore, it is difficult to achieve the ideal treatment method with Chinese herbal medicine alone. contraceptive effect

For example, the patent CN 105434501 A discloses the preparation of the Chinese herbal medicine Quantianchi extract and its application in contraceptives. It has spermicidal effect and has low toxic and side effects, but the contraceptive efficiency needs to be improved after oral administration

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