Thermo-sensitive collagen compound anti-inflammatory gel spray for treating psoriasis and preparation method thereof
A temperature-sensitive, psoriasis technology, applied in non-active ingredients medical preparations, medical preparations containing active ingredients, skin diseases, etc., can solve problems such as poor effect, skin repair, bacterial invasion, etc. Repair and treatment, prevent moisture evaporation, long-lasting effect
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Embodiment 1
[0049] Preparation of thermosensitive collagen compound anti-inflammatory gel spray for treating psoriasis
[0050] The temperature-sensitive collagen-based composite anti-inflammatory gel spray for treating psoriasis in this embodiment is made of the following raw materials in parts by weight: temperature-sensitive collagen-based composite anti-bacterial and anti-inflammatory gel 55, hemostatic drug 18, dandelion 15, forsythia 4, Salvia miltiorrhiza 3, Rhizoma Chuanxiong 2, Speranthum 6, glycerin 10, rosemary essential oil 2.5, lauric monoglyceride 2.5, water 15; its preparation method comprises the following steps:
[0051] (1) Preparation of thermosensitive collagen-based composite antibacterial and anti-inflammatory gel
[0052] Take 3 parts by weight of type I collagen and dissolve it in 300 parts by volume of 10mM hydrochloric acid solution with stirring at 7°C. After the collagen is completely dissolved, slowly add pH The Tris-NaCl buffer solution with a value of 8.0 w...
Embodiment 2
[0059] Preparation of thermosensitive collagen compound anti-inflammatory gel spray for treating psoriasis
[0060] The temperature-sensitive collagen-based composite anti-inflammatory gel spray for treating psoriasis in this embodiment is made of the following raw materials in parts by weight: temperature-sensitive collagen-based composite anti-bacterial and anti-inflammatory gel 45, hemostatic drug 15, dandelion 12, forsythia 3, Salvia miltiorrhiza 2, Rhizoma Chuanxiong 1, Speranthema 4, glycerin 8, rosemary essential oil 2, monoglyceride laurate 1.5, water 10; its preparation method comprises the following steps:
[0061] Take 1 weight part of type I collagen and dissolve it in 100 volume parts of 10mM hydrochloric acid solution with stirring at 4°C. After the collagen is completely dissolved, slowly add pH The Tris-NaCl buffer solution with a value of 8.0 was stirred evenly at 4°C to obtain the regenerated collagen fiber buffer stock solution; then the above-mentioned rege...
Embodiment 3
[0068] Preparation of thermosensitive collagen compound anti-inflammatory gel spray for treating psoriasis
[0069] The temperature-sensitive collagen-based composite anti-inflammatory gel spray for treating psoriasis in this embodiment is made of the following raw materials in parts by weight: temperature-sensitive collagen-based composite anti-bacterial and anti-inflammatory gel 65, hemostatic drug 20, dandelion 18, forsythia 5, Salvia miltiorrhiza 4, Rhizoma Chuanxiong 3, Speranium 8, glycerin 12, rosemary essential oil 3, monoglyceride laurate 3.5, water 20; its preparation method comprises the following steps:
[0070] Take 5 parts by weight of type I collagen, stir it at 10°C and dissolve it in 500 parts by volume of 10mM hydrochloric acid solution. After the collagen is completely dissolved, slowly add pH The Tris-NaCl buffer solution with a value of 8.0 was stirred evenly at 10°C to obtain the regenerated collagen fiber buffer stock solution; then the above-mentioned r...
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