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Gel used for gynecology department, and preparation method thereof

A gel and gynecological technology, applied in the field of medicine, can solve problems such as fluidity, poor flexibility and hydrophilicity, difficult to remove protein components, and easy to feel uncomfortable when used, so as to achieve the effects of not being prone to rejection, alleviating dryness and astringency, and promoting repair Effect

Inactive Publication Date: 2018-08-28
广西达庆生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Among the existing gel preparations, 1. Most vaginal gels contain chitosan, but chitosan is extracted from animal shells, the protein components inside are difficult to remove, and the molecular weight is also difficult to control, often causing adverse reactions 2. Due to the problems of fluidity, flexibility and poor hydrophilicity of traditional vaginal gels, it is easy to feel uncomfortable when used; 3. Most of the vaginal gels have a single therapeutic effect and do not have the ability to repair the vaginal mucosa. Impaired effect leading to vaginal dryness

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A gynecological gel prepared from the following raw materials:

[0038] Hyaluronic acid 0.1g, lactic acid 0.1g, levulinic acid 0.1g, luteolin 0.1g, basic fibroblast growth factor 0.001g, glycogen 0.5g, thickener 0.5g, methylparaben 0.1 g, purified water 99g.

[0039] The glycogen is a mixture of isomaltooligosaccharide, fructooligosaccharide and galactooligosaccharide.

[0040] The thickener is a mixture of hydroxypropylmethylcellulose, carbomer, sodium carboxymethylcellulose and hydroxyethylcellulose.

[0041] A preparation method of gynecological gel comprises the following steps:

[0042] (1) Take luteolin and basic fibroblast growth factor, add 0.05g of purified water at 60°C, grind and pass through a 80-mesh sieve;

[0043] (2) Take the thickener and the remaining purified water, stir evenly, and make a gel;

[0044] (3) According to the weight ratio, weigh the remaining raw materials and auxiliary materials, mix them with the suspension prepared in step (1), a...

Embodiment 2

[0045] A gynecological gel prepared from the following raw materials:

[0046]Hyaluronic acid 2g, lactic acid 3g, levulinic acid 3g, luteolin 5g, basic fibroblast growth factor 1g, glycogen 5g, thickener 8g, ethyl p-hydroxybenzoate 5g, purified water 67g.

[0047] The glycogen is a mixture of isomaltooligosaccharide and galactooligosaccharide.

[0048] The thickener is a mixture of carbomer and hydroxyethyl cellulose.

[0049] A preparation method of gynecological gel comprises the following steps:

[0050] (1) Take luteolin and basic fibroblast growth factor, add 2.5g of purified water at 100°C, after grinding, pass through a 200-mesh sieve; (2) Take the thickener and the remaining purified water, stir evenly, and prepare into a gel;

[0051] (3) According to the weight ratio, weigh the remaining raw materials and auxiliary materials, mix them with the suspension prepared in step (1), add them to the gel in step (2), and continue stirring until uniform.

Embodiment 3

[0053] A gynecological gel prepared from the following raw materials:

[0054] Hyaluronic acid 0.5g, lactic acid 1g, levulinic acid 1g, luteolin 2g, basic fibroblast growth factor 0.05g, fructooligosaccharide 2g, hypromellose 3g, propylparaben 2g, Purified water 89g.

[0055] A preparation method of gynecological gel comprises the following steps:

[0056] (1) Take luteolin and basic fibroblast growth factor, add 1g of purified water at 80°C, after grinding, pass through a 100-mesh sieve;

[0057] (2) Take the thickener and the remaining purified water, stir evenly, and make a gel;

[0058] (3) According to the weight ratio, weigh the remaining raw materials and auxiliary materials, mix them with the suspension prepared in step (1), add them to the gel in step (2), and continue stirring until uniform.

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PUM

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Abstract

The invention relates to a gel used for a gynecology department, and a preparation method thereof. The gel used for the gynecology department is prepared from hyaluronic acid, lactic acid, levulinic acid, luteolin, basic fibroblast cell growth factor, glycogen and the like. The gel has the functions of resisting bacteria, lubricating, moisturizing and treating elytritis.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a gynecological gel and a preparation method thereof. Background technique [0002] Gel preparations are very common in the treatment of gynecological diseases. For example, the patent CN201410330755.8 discloses a composition and preparation for gynecological infection. The gynecological infection composition is composed of chitosan quaternary ammonium salt and oligosaccharide in a mass ratio of 10:3 or 1:10, and contains The gel of the infection composition is made of the following raw materials in mass percentage: 5%-20% of the composition for gynecological infection, 0.1%-5% of thickener, 1%-10% of moisturizing agent and water 69.9%-85%. Patent CN201310431614.0 discloses a gel preparation for treating gynecological diseases, which is characterized in that it is composed of chitosan with specific molecular weight and deacetylation degree, chlorhexidine, glycerin, acidulant a...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K9/06A61P15/02A61K31/728A61K31/19A61K31/352A61K31/717
CPCA61K38/1825A61K47/12A61K9/0034A61K9/06A61K31/19A61K31/352A61K31/717A61K31/728A61K2300/00
Inventor 苏雪
Owner 广西达庆生物科技有限公司
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