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A preparation method of medical glue with functions of promoting healing and repairing

A technology of functions and extracts, applied in the field of medical materials, can solve problems such as side effects, affecting the effect and application of medical adhesives, and few biomedical materials have the ability to promote healing and repair scars

Active Publication Date: 2021-08-20
浙江派菲特新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the main research direction of medical adhesives is to improve the bonding strength of various adhesives. However, few biomedical materials currently used in surgical operations have the effect of promoting healing and repairing scars efficiently. Patients bring enormous mental and psychological stress, and endowing medical materials with functions of promoting healing and repairing is an effective way to solve this problem
The production of formaldehyde during the storage and use of cyanoacrylate medical adhesives has side effects on biological tissues, and with the increase of formaldehyde concentration, the damage to organisms increases, which seriously affects the effect and application of medical adhesives

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] A medical glue with functions of promoting healing and repairing, comprising the following components in parts by weight:

[0061] 20 parts of n-butyl α-cyanoacrylate, 25 parts of isooctyl α-cyanoacrylate, 2 parts of styrene-based thermoplastic elastomer microspheres, 25 parts of high-efficiency healing and repair components, 2 parts of sodium alginate, 3 parts of sodium hyaluronate, 8 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, 150 parts of compound fruit oil components, 200 parts of sterile water; highly effective healing and repair components include special effects to promote healing and 6 parts of repairing components, 12 parts of natural promoting healing and repairing components, 6 parts of traditional Chinese medicine promoting healing and repairing components; special effect promoting healing and repairing components are calculated by weight, including 2 parts of jellyfish extract, 2 parts of starfish extract 1 part of gecko ex...

Embodiment 2

[0065] A medical glue with functions of promoting healing and repairing, comprising the following components in parts by weight:

[0066] 22 parts of n-butyl α-cyanoacrylate, 28 parts of isooctyl α-cyanoacrylate, 4 parts of styrene-based thermoplastic elastomer microspheres, 30 parts of high-efficiency healing and repair components, 3 parts of sodium alginate, 4 parts of sodium hyaluronate, 9 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, 180 parts of compound fruit oil components, 200 parts of sterile water; highly effective healing and repair components include special effects to promote healing and 6 parts of repairing components, 17 parts of natural promoting healing and repairing components, 9 parts of traditional Chinese medicine promoting healing and repairing components; special effect promoting healing and repairing components are calculated in parts by weight, including 2 parts of jellyfish extract, 2 parts of starfish extract 1 part of...

Embodiment 3

[0070] A medical glue with functions of promoting healing and repairing, comprising the following components in parts by weight:

[0071] 24 parts of n-butyl a-cyanoacrylate, 33 parts of isooctyl a-cyanoacrylate, 5 parts of styrene-based thermoplastic elastomer microspheres, 35 parts of high-efficiency healing and repair components, 4 parts of sodium alginate, 5 parts of sodium hyaluronate, 10 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, 210 parts of compound fruit oil components, 200 parts of sterile water; highly effective healing and repair components include special effects to promote healing and 6 parts of repairing components, 22 parts of natural healing promoting and repairing components, 10 parts of traditional Chinese medicine promoting healing and repairing components; special effect promoting healing and repairing components are calculated by weight, including 2 parts of jellyfish extract, 2 parts of starfish extract 1 part of gecko ...

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PUM

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Abstract

The invention discloses a preparation method of medical glue with functions of promoting healing and repairing, which is characterized in that it comprises the following components in parts by weight: 20-25 parts of n-butyl cyanoacrylate, isocyanoacrylate 25‑35 parts of octyl esters, 2‑6 parts of styrene thermoplastic elastomer microspheres, 25‑37 parts of highly effective healing and repair components, 2‑4 parts of sodium alginate, 3‑6 parts of sodium hyaluronate, 8‑10 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, 150‑220 parts of compound fruit oil, 200 parts of sterile water. The medical adhesive of the present invention specially selects a variety of biological extracts with regenerative functions and adds three major healing-promoting and repairing components to promote healing and improve repairing effects, and has high bonding strength and good biocompatibility. It meets the clinical application requirements for medical adhesives.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a medical glue with functions of promoting healing and repairing and a preparation method thereof. Background technique [0002] With the advancement of medicine, the clinical requirements for the effect of surgical techniques and auxiliary materials are getting higher and higher. The requirements of modern medicine are to minimize the pain of patients, and at the same time pay more attention to the repair of scars after surgery. Especially in the medical cosmetic and plastic industry, postoperative recovery and aesthetics are particularly important. Medical adhesive is a branch of medical polymer. It takes biological tissue as the bonding object. Most of the tissues and organs of the human body can be replaced by adhesive technology during the treatment process, without anesthesia; wound healing Then it will fall off automatically. Compared with tradition...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L24/10A61L24/08A61L24/06A61L24/00
CPCA61L24/0005A61L24/001A61L24/0015A61L24/06A61L24/08A61L24/108A61L2300/204A61L2300/232A61L2300/252A61L2300/30A61L2300/404A61L2300/412C08L89/00C08L5/04C08L5/08C08L25/08
Inventor 林闪光叶善明李程辉应磊
Owner 浙江派菲特新材料科技有限公司
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