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62results about How to "Good repair function" patented technology

Guided tissue regeneration composite membrane material and preparation method thereof

ActiveCN106110407APromotes osteoblast growthPromotes periodontal ligament cell adhesionSurgeryDefect repairChemistry
The invention provides a guided tissue regeneration composite membrane material. The guided tissue regeneration composite membrane material is characterized by being in a double-layer membrane structure, wherein the double-layer membrane structure comprises a loose layer on the bottom layer and a compact layer on the upper layer. According to a second aspect, the invention provides a preparation method of the guided tissue regeneration composite membrane material. According to the guided tissue regeneration composite membrane material and the preparation method, the biological membrane material having the customized specification, having the tissue integration activity, and being capable of promoting the growth of the osteoblasts can be printed by adopting a three-dimensional printer, a material with the capacity of promoting the periodontal ligament cell adhesion and the periosteum cell adhesion is prepared by combining with the electrospinning technology, and a medicine having the antimicrobial activity is combined, therefore, the guided tissue regeneration composite membrane material has good biocompatibility, good bone repair function and good bacteria resisting function, and can be used for the periodontal guided tissue regeneration treatment and periosteum defect repair.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Preparation method of small molecule peptides of vinasse and application of small molecule peptides of vinasse in skin care products

The invention provides a preparation method of small molecule peptides of vinasse and application of small molecule peptides of vinasse in skin care products. The preparation method comprises the following steps: S1, carrying out vacuum extrusion, cooling, crushing and sieving on vinasse, the water content of which is 11-22%; S2, carrying out alkali dissolution and acid settlement on the vinasse expanded powder obtained in the S1 to extract vinasse proteins so as to obtain vinasse protein extract; and S3, carrying out hydrolysis on the vinasse protein extract extracted in the S2 with proteolytic enzymes, and carrying out enzyme deactivation, filtration, concentration, freezing and drying to obtain the small molecule peptides of vinasse. By deeply processing the vinasse by adopting a special vacuum expansion technology, the extraction ratio of the vinasse proteins is increased effectively; meanwhile, by adopting the special proteolytic enzymes, the small molecule peptides of vinasse with relatively good moisturizing and repairing functions can be obtained. In addition, the small molecule peptides of vinasse are applied to skin care products, so that the moisturizing and repairing functions of the skin care products are improved while the additional value of the vinasse is increased.
Owner:GUANGDONG MARUBI BIOLOGICAL TECH CO LTD

Preparation method of bone repair hydrogel and fiber pipe composite material loading growth factors

The invention discloses a preparation method of a bone repair hydrogel and fiber pipe composite material loading growth factors. Firstly, a spinning solution is prepared, the spinning solution is arranged in a syringe, a nanometer fiber reticular layer is prepared by high-voltage electrospinning, sodium alginate modified by RGD (Arg-Gly-Asp) is irradiated with gamma rays, and after irradiation, the RGD-sodium alginate is filtered to be degermed and is stored at the room temperature of -20 DEG C so as to prepare hydrogel. According to the method disclosed by the invention, the sodium alginate degraded by gamma ray irradiation can be combined with adhesive peptide in covalence to promote cell attachment; a nanometer fiber pipe is prepared through electrostatic spinning, the fiber has a diameter being the same as that of an extracellular matrix (ECM) and a large specific surface area, can improve cell attachment and migration, and is suitable for osteoblast differentiation and stem cell in vitro regeneration; and the composite material consisting of the bone repair hydrogel and the fiber pipe can guide bone regeneration by hydrogel injected with the sodium alginate and the protein electrostatic spinning nanometer fiber reticular film, promotes the regeneration and repair functions of vessels, can be used as a bone repair transmission system, has a simple production process and is easy to operate.
Owner:WUXI ZHONGKE GUANGYUAN BIOMATERIALS

Antibody-based targeting medicine used for repairing damaged tissues, administration method, and magnetic resonance imaging contrast agent

The invention discloses an antibody-based targeting medicine used for repairing damaged tissues. The medicine comprises stem cell specific antibodies and damaged part specific antibodies. The stem cell specific antibodies and damaged part specific antibodies are directly or simultaneously coupled on nano-grade or micron-grade iron particles through chemical covalent bonds. During an administration process employing the targeting medicine obtained by coupling the specific antibodies and the iron particles, and after the administration process, a lesion area can be covered by using an external magnetic field. The targeting medicine obtained by coupling the specific antibodies and the iron particles can also be used as an MRI contrast agent. The antibody-based targeting medicine used for repairing damaged tissues is safe and reliable. With the medicine, human body intrinsic stem cell reparation function can be optimized, and effector molecules can be delivered with targets. Therefore, a novel safe treatment means with advantages of high-efficiency reparation, no toxicity, and no side effect can be provided. With the external magnetic field, the targeting effect of the medicine can be improved, and side effect can be reduced. Also, the antibody-based targeting medicine used for repairing damaged tissues can actively identify cardiovascular lesions, such that the medicine can be used as an MRI contrast agent.
Owner:SUZHOU WANMUCHUN BIOLOGICAL TECH

Skin care product containing bird's nest peptides and preparation method of skin care product

The invention relates to a skin care product containing bird's nest peptides and a preparation method of the skin care product and belongs to the technical field of skin care products. The skin care product is prepared from the following raw materials in parts by weight: 10-25 parts of bird's nest peptides, 5-20 parts of pearl essence, 1-5 parts of tetrahydrocurcumin, 0-15 parts of a green tea extract and 15-35 parts of a grape seed extract. The bird's nest peptide is capable of reducing and preventing melanosis, and has excellent effects of fading spots, whitening and repairing; the tetrahydrocurcumin has an obvious antioxidant effect; the pearl essence is capable of inhibiting melanin synthesis, has an effect of scavenging free radicals and contributes to fading spots, whitening and delaying skin aging; the green tea extract is capable of eliminating ultraviolet-induced free radicals so as to protect normal functions of melanin cells and inhibiting melanogenesis, and pigmentation canbe reduced; the grape seed extract is capable of fading pigments. Moreover, the skin care product has excellent effects of moisturizing and moistening. Due to co-actions of the multiple raw materials, the effects of removing beverage, whitening and repairing the skin can be achieved.
Owner:FOSHAN UNIVERSITY

Wear-resistant self-repairing polyurethane composite coating agent based on shape memory and preparation method thereof

The invention discloses a wear-resistant self-repairing polyurethane composite coating agent based on shape memory and a preparation method thereof, and belongs to the technical field of coating agent production. The preparation method comprises the following steps: carrying out prepolymerization reaction on polyester diol and diisocyanate to obtain an isocyanate group-terminated prepolymer; and introducing a monomer for forming quadruple hydrogen bonds and a ligand containing a metal coordination bond structural unit into the prepolymer to obtain the wear-resistant self-repairing polyurethane composite coating agent based on shape memory. The process is simple, easy to control and suitable for industrial production. Quadruple hydrogen bonds and metal ion coordination bonds are used as sacrifice bonds to dissipate energy and improve toughness and strength through a cross-linking effect, and self-repairing efficiency is promoted through interaction among molecular chains; a shape memory effect is realized by utilizing the crystallization reversibility of a molecular chain, and deformation caused by friction or self-repairing is prevented; and the wear-resistant self-repairing polyurethane composite coating agent is good in stability, excellent in tribological performance and high in repairing efficiency and can be applied to various fields.
Owner:SHAANXI UNIV OF SCI & TECH +1

Compound preparation for treating rhinosinusitis

The invention relates to a Chinese patent medicine compound preparation and particularly relates to a compound preparation for treating rhinosinusitis. The compound preparation is characterized by containing the water extract and decoction of fresh and mature fig, arborvitae tops, echinacea, baikal skullcap root, cocklebur fruit and liquorice, then ethanol precipitation is carried out, the supernatant liquid is taken and concentrated into clear paste, and the clear paste, sucrose and dextrin are uniformly mixed and then dried to be prepared into tablets or particles. The compound preparation provided by the invention has the functions of clearing away heat and toxic material, reducing swelling and alleviating pain, expelling wind and removing dampness, purging fire for removing toxin, promoting blood circulation and arresting bleeding, enhancing the immunity and resistance of the organism, improving symptoms and promoting nasal cavity and nasal sinus mucosa functions, and does not have toxic and side effects. Clinical applications prove that the compound preparation provided by the invention has obvious curative effects on postoperative recovery of acute and chronic rhinitis, paranasal sinusitis, rhinopharyngitis and nose and sinus parts, adjuvant therapy of malignant tumors at the parts and especially postoperative radiotherapy of patients, and has the obvious advantages of good performance, easiness in preparation, low cost, no toxic and side effects and the like.
Owner:刘艳
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