Bacteriostatic formulation for female pudendum nursing

A genital and formula technology, applied in pharmaceutical formulas, topical antibacterial agents, medical preparations containing active ingredients, etc., can solve the problems of Lactobacillus losing its advantages, not having the effect of premature vaginal aging, and lack of nursing effect, etc. Moisturizing the genitals, repairing the damaged mucosa of the genitals, easy to accept effects

Inactive Publication Date: 2018-10-23
广州蜜蜜健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In daily life, more and more attention is paid to the care of female genitals. The vaginal flora is relatively complex, and the microorganisms in it are further divided into pathological and commensal. Various microorganisms grow in the same environment, and there may be resistance between each microorganism. Antagonistic effect, when the pH value is 3.8-4.2, it is beneficial to the reproduction of commensal bacteria, especially Lactobacillus, which is an important bacterial species to ensure vaginal health, and can inhibit the reproduction of harmful microorganisms. The vaginal flora restrict each other, but once The balance is destroyed, the PH value in the vagina is not suitable for the growth of Lactobacillus, Lactobacillus loses its advantage, and pathological bacteria multiply, and symptoms will appear. The existing antibacterial liquid for female genital care has a certain antibacterial effect, but it lacks antibacterial effects. It does not have the function of vaginal maintenance to prevent premature aging of the vagina. Therefore, a kind of antibacterial formula for female genital care is proposed

Method used

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  • Bacteriostatic formulation for female pudendum nursing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] First prepare the sage extract:

[0018] 1) Crush the sage to 40 mesh and add it to the container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, put it at room temperature for 11h, then filter the mixture, and dry the filtrate at room temperature until constant Heavy;

[0019] 2) Add acetone with a mass fraction of 50% to the preparation in step 1, the ratio of solid to liquid is 1:50g / ml, and carry out ultrasonic extraction under normal pressure and at a temperature of 35°C, the extraction time is 100min, and filter after extraction Get sage extract.

[0020] Then prepare the oat extract:

[0021] 1) Grind the oats to 40 mesh and put them in a container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, put it at room temperature for 9h, then filter the mixture with ethanol solution with a mass fraction of 80%. Soak the filtered matter, the number of soaking times is 2 times, and the soaking time is 20 minutes each time, filte...

Embodiment 2

[0027] First prepare the sage extract:

[0028] 1) Grind sage to 40 mesh and add it to a container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, place it at room temperature for 12h, then filter the mixture, and dry the filtrate at room temperature until constant Heavy;

[0029] 2) Add acetone with a mass fraction of 50% to the preparation in step 1, the ratio of solid to liquid is 1:50g / ml, and carry out ultrasonic extraction under normal pressure at a temperature of 38°C for 107 minutes, and filter after extraction Get sage extract.

[0030] Then prepare the oat extract:

[0031] 1) Grind oats to 40 mesh and put them in a container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, leave it at room temperature for 10h, then filter the mixture, and use an ethanol solution with a mass fraction of 80%. Soak the filtered matter, the number of soaking times is 2 times, and the soaking time is 23 minutes each time, filter out the soaked ...

Embodiment 3

[0037] First prepare the sage extract:

[0038] 1) Grind sage to 40 mesh and add it to a container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, place it at room temperature for 12h, then filter the mixture, and dry the filtrate at room temperature until constant Heavy;

[0039] 2) Add acetone with a mass fraction of 50% to the preparation in step 1, and the ratio of solid to liquid is 1:50g / ml. Ultrasonic extraction is carried out under normal pressure and at a temperature of 42°C. The extraction time is 114min. After extraction, filter Get sage extract.

[0040] Then prepare the oat extract:

[0041] 1) Grind oats to 40 mesh and put them in a container, then add petroleum ether, the ratio of solid to liquid is 1:10g / ml, leave it at room temperature for 10h, then filter the mixture, and use an ethanol solution with a mass fraction of 80%. Soak the filtered matter, the number of soaking times is 3 times, and the soaking time is 26 minutes each time, f...

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Abstract

The invention discloses the technical field of female hygienic aids, and particularly relates to a bacteriostatic formulation for female pudendum nursing. The bacteriostatic formulation is composed ofradix sophorae flavescentis, centella, fructus cnidii, camellia, rhizoma bletillae, myrrh, salvia officinalis extract, oat extract, beetroot, aleo vera extract, cinnamoum verum, propylene glycol, Carbomer and purified water. The salvia officinalis extract is rich in diterpene, triterpene, flavone and various phenol compounds, and polyphenol has high antioxidation ability due to presence of conjugated cyclic structure and hydroxyl; polyphenol is combined with active oxygen through hydrogenation action to form a stable compound to remove free radicals in the process of oxidation; chelated metalions can slow down the oxidation process, so that the salvia officinalis extract has efficacy of relieving female pudendum aging; the oat extract is identical with the saliva officinalis extract in efficacy and contains glucan, flavone compounds and various antioxidation substances, thereby being capable of further relieving female pudendum aging.

Description

technical field [0001] The invention relates to the technical field of female hygiene products, in particular to an antibacterial formula for female genital care. Background technique [0002] In daily life, more and more attention is paid to the care of female genitals. The vaginal flora is relatively complex, and the microorganisms in it are further divided into pathological and commensal. Various microorganisms grow in the same environment, and there may be resistance between each microorganism. Antagonistic effect, when the pH value is 3.8-4.2, it is beneficial to the reproduction of commensal bacteria, especially Lactobacillus, which is an important bacterial species to ensure vaginal health, and can inhibit the reproduction of harmful microorganisms. The vaginal flora restrict each other, but once The balance is destroyed, the PH value in the vagina is not suitable for the growth of Lactobacillus, Lactobacillus loses its advantage, and pathological bacteria multiply, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P15/02A61P31/02
CPCA61K36/185A61K36/23A61K36/234A61K36/328A61K36/489A61K36/537A61K36/54A61K36/82A61K36/886A61K36/896A61K36/898A61K36/899A61K2236/331A61K2236/51A61P15/02A61P31/02A61K2300/00
Inventor 王晓方
Owner 广州蜜蜜健康科技有限公司
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