MEEK skin grafting material combined with allogenic skin graft

An allogeneic, skin grafting technology, applied in skin transplantation, prosthesis, medical science, etc., can solve the problems of no biological activity, increase the disability, mortality, and danger of burn patients, and achieve an improved therapeutic effect. Effect

Active Publication Date: 2018-11-06
FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, within three weeks or so, before the autologous skin graft has expanded and fused, the wound that is not covered by the autologous skin graft is only covered by polyamide double pleated yarn. As a kind of textile, polyamide double pleated yarn is not It is biologi

Method used

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  • MEEK skin grafting material combined with allogenic skin graft
  • MEEK skin grafting material combined with allogenic skin graft
  • MEEK skin grafting material combined with allogenic skin graft

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Such as figure 1 , figure 2 , Figure 9 , a MEEK skin grafting material combined with an allogeneic skin graft, comprising a MEEK crepe sheet and an allogeneic skin graft 50, the MEEK crepe sheet includes a metal film layer 10 and a gauze layer 20 laminated together. The gauze layer is a water-soluble fabric layer.

[0039] The metal film layer is an aluminum foil layer.

[0040]Water-soluble fabrics are soluble fabrics made from cellulose, such as using the methods described in Chinese patent documents CN1286329A, CN1143697A, and CN1058342A to make soluble fabrics. The use of cellulose as a raw material is based on the following considerations: Among various absorbable materials such as gelatin, collagen, starch, cellulose, etc., only the material made of cellulose (or regenerated cellulose) has the characteristics of being thin, soft and foldable , and the fabric can be folded, which is an essential key feature for the preparation of MEEK skin grafting materials....

Embodiment 2

[0051] A kind of MEEK skin grafting material combined with allogeneic skin graft, this embodiment is a structural replacement of Embodiment 1.

[0052] In this embodiment, the unfolded length of each transverse pleat of the MEEK crepe sheet is the same, which is S1=11.0mm, and the developed length of each longitudinal pleat is the same, which is S2=11.0mm, such as Figure 8 shown.

[0053] Since the unfolded lengths of the transverse folds and longitudinal folds are both 11.0 mm, the area corresponding to a piece of micro-skin graft after unfolding is 17 mm×17 mm=289 square millimeters, which is equivalent to expanding the skin grafting area of ​​the autologous skin graft by 8 times, namely The expansion ratio of MEEK crepe sheets is 1:8.

Embodiment 3

[0055] A kind of MEEK skin grafting material combined with allogeneic skin graft, this embodiment is a structural replacement of Embodiment 1.

[0056] In this embodiment, the unfolded length of each transverse pleat of the MEEK crepe sheet is the same, which is S1=14.8mm, and the unfolded length of each longitudinal pleat is the same, which is S2=14.8mm, such as Figure 8 shown.

[0057] Since the unfolded length of the transverse and longitudinal folds is 14.8mm, the area corresponding to a micro-skin graft after unfolding is 20.8mm×20.8mm=432.6mm2, which is equivalent to expanding the area of ​​the autologous skin graft by 12 times , that is, the expansion ratio of MEEK crepe sheets is 1:12.

[0058] The expansion ratio of the usual MEEK crepe sheet is not less than 1:4. In the above examples, the MEEK skin graft material combined with allogeneic skin grafts was used. According to clinical experience, the expansion ratio of MEEK crepe sheets can reach 1:12, which signific...

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Abstract

The invention relates to a MEEK skin grafting material combined with an allogenic skin graft. The MEEK skin grafting material comprises a MEEK crepe piece and the allogenic skin, wherein the MEEK crepe piece comprises a metal film layer and a gauze layer which are stacked together; the gauze layer is a water-soluble fabric layer. The MEEK skin grafting material disclosed by the invention has the beneficial effects that the MEEK crepe piece is combined with the allogenic skin graft to cover burned wounds, two burn treating methods are perfectly combined, and a treating effect of MEEK skin grafting is remarkably improved.

Description

technical field [0001] The invention belongs to medical skin grafting materials, in particular to a MEEK skin grafting material combined with allogeneic skin grafts. Background technique [0002] MEEK skin grafting technology is a skin grafting technology originated in the Netherlands. It is a surgical technique for micro-skin grafting created and developed in continental Europe. Since the development of MEEK skin grafting technology, Dutch hospitals have first applied it in burn surgery, especially for skin donors. There is a shortage of patients with extensive deep burns. The core of MEEK skin-grafting technology is the MEEK skin-grafting crepe sheet. The crepe sheet includes metal film layers and gauze layers laminated together. The crepe sheet is provided with horizontal and vertical wrinkles of the same size and interval; Cut into multiple square miniature skin grafts at intervals, stick them on the crepe sheet in a way corresponding to the folds, unfold the folds of t...

Claims

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Application Information

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IPC IPC(8): A61L27/36A61L27/60A61F2/10
CPCA61F2/105A61L27/362A61L27/60
Inventor 李峰
Owner FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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