Preparation method of mesoporous magnetic particles

Abstract

The patent of invention discloses a preparation method of mesoporous magnetic particles. A needed comprises deionized water, anhydrous alcohol, an ammonia solution, ferric chloride hexahydrate, waterless sodium acetate, tetraethyl orthosilicate, sodium dodecyl benzene sulfonate, ethylene glycol, N-(2-aminoethyl)-3-(3-aminopropyl)trimethoxysilane, cetyl trimithyl ammonium bromide and acetone. Needed equipment comprises a vacuum drying oven, a magnetic separator, an ultrasonic cleaning apparatus, a stirring machine, an airtight reactor and a high-temperature oven. The preparation method comprises the following steps of: preparing magnetic particles, generating silicon dioxide coating, performing amino modification and forming particle mesoporous. According to the preparation method disclosedby the invention, a hydrothermal synthesis method is improved, demands for a reaction container are reduced, particle distribution is concentrated, particle diameter is homogeneous, the steps are simplified, the prepared magnetic particles have mesoporous and are larger in surface area, and a preparation method of mesoporous magnetic particles simple and convenient to operate, low in equipment requirements, homogeneous in particle diameter of particles, high in particle adsorption efficiency and large in adsorption capacity is provided.

Description

technical field [0001] The invention relates to the field of DNA extraction, in particular to a method for preparing mesoporous magnetic particles. Background technique [0002] DNA contains a large amount of genetic information, and research on it can provide an in-depth understanding of various traits and characteristics of organisms. Therefore, since DNA was discovered, related research on DNA has never stopped, and many biological characteristics have been discovered. Some disease diagnosis and medical treatment measures have also been obtained through research and development, providing a strong boost to medical progress and the development of biotechnology, and also providing the necessary guarantee for people's health. [0003] DNA directly affects or even determines all the characteristics of organisms, so research on it is conducive to promoting the progress of social medical level, but also because of this, if DNA is directly studied, it contains many biological tr...

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Problems solved by technology

[0006] The purpose of the present invention is to solve the problems of high equipment requirements, non-concentrated particle distribution, low DNA adsorption efficiency, and small adsorption capacity in the preparation of magnetic particles for DNA extraction and the DNA extraction process, and provide a magnetic particle that is easy to operate, low in equipment requirements, and a particle Preparation method of mesoporous magnetic particles with uniform particle size, high particle adsorption efficiency and large adsorption capacity

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