Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of purposes of Zanthoxylum bungeanum leaf total flavonoids extract

A technology of prickly ash leaves and total flavonoids is applied in the directions of medical preparations, drug combinations, and plant raw materials containing active ingredients, and can solve the problems of insufficient development and utilization, waste of resources and the like.

Active Publication Date: 2021-09-14
LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a by-product of Zanthoxylum bungeanum, Zanthoxylum bungeanum leaf resources are abundant, but the degree of development and utilization is insufficient, resulting in waste of resources

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of purposes of Zanthoxylum bungeanum leaf total flavonoids extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] First prepare the total flavonoids extract of Zanthoxylum bungeanum leaves according to the following steps:

[0025] (1) Wash the pepper leaves, dry them in the shade, and then crush them to a fineness of 0.1mm;

[0026] (2) Heat and reflux the pulverized Zanthoxylum bungeanum leaves with water for extraction at a heating temperature of 100°C, extract 3 times, each extraction takes 2.0 hours, the mass ratio of Zanthoxylum bungeanum leaves and water is 1:10, filter after extraction, and combine the filtrates, Then concentrate to obtain the crude extract A of total flavonoids;

[0027] (3) Fully dissolve the crude extract of total flavonoids from Zanthoxylum bungeanum leaves in water, and pass through D-101 macroporous adsorption resin column. Add water and crude extract to the column respectively, let it stand for adsorption for 24 hours, and then use 3.5 times BV of pure water, 30% methanol, 60% methanol, 85% methanol and methanol to elute in sequence. Concentrate to...

Embodiment 2

[0031] First prepare the total flavonoids extract of Zanthoxylum bungeanum leaves according to the following steps:

[0032] (1) Wash the pepper leaves, dry them in the shade, and then grind them to a fineness of 0.2 mm;

[0033] (2) The pulverized Zanthoxylum bungeanum leaves are extracted by cold soaking at room temperature with a mixed solution of methanol / water with an extraction solvent volume percentage of 80%, and the pulverized Zanthoxylum bungeanum leaves are soaked in the extraction solvent for 7 days, and the Zanthoxylum bungeanum leaves and the volume percentage The mass ratio of the mixed solution of 80% methanol / water is 1:5, extracting 3 times, filtering after extraction, merging the filtrate, and then concentrating to obtain the crude extract A of total flavonoids;

[0034] (3) According to the operation of step (3) in Example 1, extracts A (pure water), B (30% methanol), C (60% methanol), D (85% methanol) and E (methanol) were obtained ;

[0035] (4) Sodium ...

Embodiment 3

[0038] First prepare the total flavonoids extract of Zanthoxylum bungeanum leaves according to the following steps:

[0039] (1) Wash the prickly ash leaves, dry them in the shade, and then grind them to a fineness of 0.3 mm;

[0040] (2) The pulverized Zanthoxylum bungeanum leaves are subjected to percolation extraction with a mixed solution of ethanol / water with an extraction solvent volume percentage of 80%. Soak in the solution for 20 h, then carry out leakage extraction, the mass ratio of the pepper leaves and the mixed solution of 75% ethanol / water by volume percentage is 1:15, after extraction, filter, combine the filtrate, and then concentrate to obtain the total flavonoids crude Extract A;

[0041] (3) According to the operation of step (3) in Example 1, extracts A (pure water), B (30% methanol), C (60% methanol), D (85% methanol) and E (methanol) were obtained ;

[0042] (4) Sodium nitrite-aluminum nitrate method was used to determine the content of total flavonoi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses the use of a total flavonoid extract from Zanthoxylum bungeanum leaves. The total flavonoids extract from Zanthoxylum bungeanum leaves described in the invention can well improve the learning and memory of the transgenic fruit fly Alzheimer's disease model, and is useful in the treatment of Alzheimer's disease. Drugs for Alzheimer's disease work well.

Description

technical field [0001] The present invention specifically relates to the use of a total flavonoid extract from Zanthoxylum bungeanum leaves. Background technique [0002] Zanthoxylum bungeanum is Rutaceae Zanthoxylum bungeanum ( Zanthoxylum bungeanum ) of dry mature leaves. "Compendium of Materia Medica" records that "Prickly ash leaves are pungent, non-toxic, hot, and can cure cold accumulation, scabies, beriberi, antiseptic, sterilization, cholera tendons, paint sores, insecticide, etc." Zanthoxylum bungeanum is widely used in daily life. As a by-product of Zanthoxylum bungeanum, Zanthoxylum bungeanum leaf resources are abundant, but the degree of development and utilization is insufficient, resulting in waste of resources. It is an important measure of the national strategy of "targeted poverty alleviation" to develop and utilize pepper leaf resources to enhance its use value in the fields of pharmaceuticals, health products, functional foods, food additives, cosmetics...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P25/28A61K127/00
CPCA61K36/758A61P25/28
Inventor 杨军丽孟宪华师彦平
Owner LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com