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Preparation method of pharmaceutical composition used for treating chronic pharyngitis

A technology for chronic pharyngitis and composition, which is applied in the field of preparation of pharmaceutical compositions, which can solve the problems of children with chronic pharyngitis being unsuitable, obvious side effects, and single effect, and achieve the effects of improving bioavailability, small side effects, and simple preparation method

Inactive Publication Date: 2019-03-05
闵键
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the drugs on the market are single-effect, expensive, and have obvious side effects. They are not suitable for children suffering from chronic pharyngitis. Therefore, it is urgent to research and develop a compound medicament for the treatment of chronic pharyngitis with good curative effect, low cost and little side effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Party:

[0017] 50 parts of hemp seed, 30 parts of afternoon tea, 25 parts of psyllium, 10 parts of Baiqian, 10 parts of lily, 2 parts of Ligustrum lucidum, and 3 parts of borneol.

[0018] Preparation:

[0019] (1) The above-mentioned raw materials are weighed according to the formula ratio, the dried hemp seeds, noon tea, and plantain seeds are crushed through a 120-mesh sieve, the medicinal noodles are immersed in water, decocted with a slow fire, and the combined decoction is filtered to obtain filtrate A;

[0020] (2) Dry and grind Baiqian, Lily, Ligustrum lucidum, and Borneolum, pass through a 60-mesh sieve, add distilled water twice the total weight of Baiqian, Lily, Ligustrum lucidum, and Borneolum, heat and boil, filter after cooling, and filtrate B spare;

[0021] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 70% and soak for 4 hours, after all the ethanol volatilizes, add distilled water to mix, concentrate and dry to obtain conce...

Embodiment 2

[0024] Party:

[0025] 65 parts of marijuana, 45 parts of afternoon tea, 40 parts of plantain seed, 18 parts of Baiqian, 15 parts of lily, 4 parts of Ligustrum lucidum, and 5 parts of borneol.

[0026] Preparation:

[0027] (1) The above-mentioned raw materials are weighed according to the formula ratio, the dried hemp seeds, noon tea, and plantain seeds are crushed through a 150-mesh sieve, the medicinal noodles are immersed in water, decocted with a slow fire, and the combined decoction is filtered to obtain filtrate A;

[0028] (2) Grind Baiqian, Lily, Ligustrum lucidum, and Borneolum after drying, pass through an 80-mesh sieve, add distilled water 4 times the total weight of Baiqian, Lily, Ligustrum lucidum, and Borneolum, heat to boil, filter after cooling, and filtrate B spare;

[0029] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 80% and soak for 4 hours, after all ethanol volatilizes, add distilled water to mix, concentrate and dry to obta...

Embodiment 3

[0032] Party:

[0033] 58 parts of marijuana, 38 parts of afternoon tea, 32 parts of plantain seed, 14 parts of Baiqian, 12 parts of lily, 3 parts of Ligustrum lucidum, 4 parts of borneol.

[0034] Preparation:

[0035] (1) The above-mentioned raw materials are weighed according to the formula ratio, the dried hemp seeds, noon tea, and plantain seeds are crushed through a 135-mesh sieve, the medicinal noodles are immersed in water, decocted with a slow fire, and the combined decoction is filtered to obtain filtrate A;

[0036] (2) Dry and grind Baiqian, Lily, Ligustrum lucidum, and Borneolum, pass through a 70-mesh sieve, add distilled water three times the total weight of Baiqian, Lily, Ligustrum lucidum, and Borneolum, heat and boil, filter after cooling, and filtrate B spare;

[0037] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 75% and soak for 3 hours, after all the ethanol volatilizes, add distilled water to mix, concentrate and dry to obtai...

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PUM

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Abstract

The invention discloses a preparation method of a pharmaceutical composition used for treating chronic pharyngitis. The preparation method comprises following steps: 1, dried semen cannabis, Wushi tea, and Plantain seed are crushed and sieved, are subjected to immersion in water, and decoction with slow fire, obtained decoction solution is mixed and filtered so as to obtain a filtrate A; 2, cynanchum root and rhizome, lily bulb, glossy privet fruit, and borneol are dried, grinded, and sieved so as to obtain a mixture, distilled water with a weight amount of 2 to 4 times of that of the mixtureis added, and cooling and filtering are carried out so as to obtain a filtrate B for further processing; 3, the filtrate A and the filtrate B are mixed, ethanol is added for immersion, distilled wateris added for uniform mixing, and concentration and drying are carried out so as to obtain a concentrate C; and 4, an accessory ingredient is added into the concentrate so as to obtain a finished product dosage needed by clinical treatment. Compared with the prior art, the advantages are that: the pharmaceutical composition can be used for treating chronic pharyngitis effectively, is low in cost and excellent in treatment effect, and is suitable for children with chronic pharyngitis to use; side effect is little; the preparation method is simple; both human labor and cost are saved; the best utilization of the raw materials is realized; and the bioavailability is increased.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a preparation method of the pharmaceutical composition for treating chronic pharyngitis. Background technique [0002] Chronic pharyngitis is chronic inflammation of pharyngeal mucosa, submucosal and lymphoid tissues. Diffuse pharyngeal inflammation is often a part of chronic inflammation of the upper respiratory tract; localized pharyngeal inflammation is mostly inflammation of pharyngeal lymphoid tissue. Primary disease is common in clinic, and the course of disease is long, and symptom is easy to show effect repeatedly. Chronic pharyngitis is more common in adult, and children also can occur. Systemic symptoms are not obvious, mainly local symptoms. Various types of chronic pharyngitis symptoms are roughly similar and varied, such as pharyngeal discomfort, foreign body sensation, pharyngeal secretions that are difficult to spit out, pharyngeal itching, burning, dryness or irr...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P11/04A61K31/045
CPCA61K36/8998A61K31/045A61K36/00A61K36/23A61K36/232A61K36/233A61K36/236A61K36/237A61K36/238A61K36/27A61K36/284A61K36/346A61K36/484A61K36/532A61K36/535A61K36/575A61K36/60A61K36/634A61K36/638A61K36/68A61K36/734A61K36/752A61K36/82A61K36/8967A61K2236/331A61K2236/51A61K2300/00
Inventor 闵键
Owner 闵键
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