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Avermectin emulsion preparation, and preparation method and application thereof

A technology of abamectin and emulsifier, which is applied in the field of pesticides and can solve the problems of lack of sustained release performance and short duration of effect

Active Publication Date: 2019-03-12
SILICON GENE TECH (SHANGHAI) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the microemulsion of avermectin has a wide range of applications, it does not have a sustained release performance and causes a short duration of action, and uses toxic solvents such as cyclohexanone and N,N-dimethylformamide

Method used

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  • Avermectin emulsion preparation, and preparation method and application thereof
  • Avermectin emulsion preparation, and preparation method and application thereof
  • Avermectin emulsion preparation, and preparation method and application thereof

Examples

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preparation example Construction

[0122] In a specific embodiment of the present invention, the preparation method of Abamectin nanoemulsion comprises the steps:

[0123] S1: Weigh avermectin, solvent, vegetable oil and stabilizer, add them to container A, mix and stir evenly;

[0124] S2: Add emulsifier, synergist and defoamer to the container A, stir evenly to form an oil phase;

[0125] S3: Weigh the dispersant, antifreeze and water, add them into container B together, mix and stir evenly, and form the water phase;

[0126] S4: adding the water phase into the oil phase, and performing high-speed shear emulsification to prepare the homogeneous and transparent abamectin nanoemulsion.

[0127] The above-mentioned abamectin nanoemulsion is prepared by the emulsified oil method or the emulsified water method, and the particle diameter of the nanoparticles in the nanoemulsion is preferably 15-25nm. This endows the abamectin nanoemulsion with better dispersibility and is easy to penetrate into the target body, w...

Embodiment 1

[0136] The avermectin nano-emulsion of the present embodiment, with avermectin as active ingredient, is equipped with solvent, vegetable oil, stabilizer, dispersant, emulsifier, synergist, antifreeze agent, defoamer, water to form avermectin Mycocin nanoemulsion. Contains by mass percentage:

[0137] Abamectin: 5%

[0138] Solvent: 25%

[0139] Vegetable oil: 1%;

[0140] Light stabilizer: 1.5%;

[0141] Emulsifier: 15%

[0142] Synergist: 3%;

[0143] Dispersant: 2%;

[0144] Antifreeze: 5%;

[0145] Defoamer: 0.01%;

[0146] Soft water: 42.49%

[0147] Among them, the solvent is a combination of propylene glycol diacetate, methyl methyl carbamate, N-ethylpyrrolidone, dimethyl sulfoxide and N,N-dimethyldecylamide, wherein 10.5% of propylene glycol diacetate, Methyl carbamate 1.5%, N-ethylpyrrolidone 1.5%, dimethyl sulfoxide 1.5%, N,N-dimethylcaprylamide 10%, based on the total weight of the emulsion; vegetable oil is cashew nut shell oil; light The stabilizer is BH...

Embodiment 2

[0150] The avermectin nano-emulsion of the present embodiment, with avermectin as active ingredient, is equipped with solvent, vegetable oil, stabilizer, dispersant, emulsifier, synergist, antifreeze agent, defoamer, water to form avermectin Mycocin nanoemulsion. Contains by mass percentage:

[0151] Abamectin B2: 5%

[0152] Solvent: 25%;

[0153] Vegetable oil: 1%;

[0154] Stabilizer: 1.5%

[0155] Emulsifier: 15%;

[0156] Synergist: 3%

[0157] Dispersant: 2%;

[0158] Antifreeze: 5%;

[0159] Defoamer: 0.01%;

[0160] Soft water: 42.49%

[0161] Among them, the solvent is a combination of propylene glycol diacetate, methyl methyl carbamate, N-ethylpyrrolidone, dimethyl sulfoxide and N,N-dimethyldecylamide propylene glycol diacetate 10.5%, methyl Methyl carbamate 1.5%, N-ethylpyrrolidone 1.5%, Dimethyl sulfoxide 1.5%, N,N-Dimethylcaprylamide 10%, based on the total weight of the emulsion; Vegetable oil is cashew nut shell oil; Stabilizer It is BHT; the emulsifi...

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Abstract

The invention provides an avermectin emulsion preparation, and a preparation method and application thereof, and particularly provides a pesticide preparation. The pesticide preparation is prepared from the following components in percentage by weight: 0.1-10% of avermectin, 5-45% of an organic solvent, 5-20% of an emulsifier, 0.5-3% of a stabilizer, and water, specifically, the organic solvent comprises propylene glycol diacetate and methyl methyl-carbamate. The pesticide preparation has a good killing effect on pests, long-lasting effect, quick-acting effect, good repellent effect and killing effect on pests and has a wide insecticidal spectrum, and is convenient to use, low in cost, safe and reliable. The pesticide preparation has the characteristics of high efficiency, low toxicity andlow pesticide cost.

Description

technical field [0001] The invention belongs to the field of pesticides, in particular, the invention relates to an abamectin emulsion preparation, a preparation method and an application thereof. Background technique [0002] Abamectin is a widely used agricultural or veterinary fungicide, insecticide and acaricide. A class of sixteen-membered macrolide disaccharide compounds with bactericidal, insecticidal, acaricidal, and nematicidal activities first developed by Satoshi Omura of Kitasato University in Japan and Merck in the United States are natural products isolated from soil microorganisms. It has stomach poisoning and contact killing effects on insects and mites, and has weak fumigation effect without systemic effect. The mechanism of action is different from general insecticides in that it interferes with neurophysiological activities and stimulates the release of GABA, which inhibits nerve conduction in arthropods. Mite adults, nymphs and insect larvae will appear...

Claims

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Application Information

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IPC IPC(8): A01N25/04A01N43/90A01P3/00A01P1/00A01P7/04A01P7/02
CPCA01N25/04A01N43/90
Inventor 唐雪明陆一鸣马樱芳
Owner SILICON GENE TECH (SHANGHAI) CO LTD
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