33 results about "Methylcarbamic acid" patented technology

The invention discloses a synthesizing method of (S)-N-ethyl-3-[(1-dimethylamino) acetyl]-N-methyl amido phenyl formate, which is characterized by the following: adopting m-hydroxy acetophenone as raw material; synthesizing intermediate 3-(1-(dimethylamino) ethyl) phenol; condensing 3-(1-(dimethylamino) ethyl) phenol and formyl chloride to produce the product with high receiving rate.

The invention discloses a cold-resistant flame-retardant rat-proof and termite-proof communication cable. The cable comprises the following components by weight: 10-15 parts of silicone rubber, 15-20 parts of fluorinated silicone rubber, 10-15 parts of fluororubber, 3-7 parts of epoxy oil, 2-4 parts of a rare earth complex, 1-2 parts of lubricating oil, 5-15 parts of decabrominated dipheny ethane, 2-8 parts of antimonous oxide, 10-20 parts of traditional Chinese medicine extract, 2-5 parts of o-isopropylphenyl-n-methylcarbamate, 1-2 parts of paraffin, 0-5 parts of calcined clay and 1-3 parts of an antioxidant, wherein the traditional Chinese medicine extract is mixed extract of salvia japonica thunb., vervain, zanthoxylum bungeagum maxim and radix angelicae. The cable is good in cold resistance, high in tensile strength, easy to bend, convenient to construct and good in flame retardance; and the cable can be effectively prevented from being bitten by rodents, is good in rat-proof and termite-proof effects, is not cracked by frost under an outdoor low-temperature condition, ensures stable operation of communication lines, and avoids the phenomenon of an influence on operation of the communication lines caused by damage to the communication cable due to external environmental factors.

The invention relates to synthesis of N-methylmethyl carbamate, which comprises the following steps: adding dimethyl carbonate and 1,3-dimethylurea in a mol ratio of (15-1):1 and a catalyst into a stainless steel reaction kettle, wherein the catalyst accounts for 1-12 mol% of the raw material 1,3-dimethylurea; and reacting in the closed reaction kettle at 80-200 DEG C under the reaction pressure of 0.1-5.0 MPa for 0.5-10 hours to obtain the N-methylmethyl carbamate. The method has the advantages of mild reaction conditions and simple process, and is easy to operate; and the generated MMC is high in yield and easy to separate.

A wound repairing agent for landscape plants comprises raw materials in parts by weight as follows: 500-800 parts of EVA (ethylene vinyl acetate), 500-800 parts of gelatin, 100-200 parts of alum, 100-200 parts of erythromycin, 2-4 parts of 6-benzylaminopurine, 4-8 parts of dihydrozeatin, 3-6 parts of isopentenyladenine, 2-6 parts of isopentenyladenosine, 10-15 parts of indole-3-acetic acid, 5-10 parts of 1-naphthalene acetic acid, 12-18 parts of sulfamethoxazole, 10-12 parts of folpet, 1-5 parts of 2-methyl-5-nitroimidazole-1-ethanol, 1-3 parts of deltamethrin, 1-5 parts of acetofenate and 2-8 parts of 1-naphthyl N-methylcarbamate. The wound repairing agent can accelerate wound repairing, has a synergistic effect by adopting various auxins and cytokinins and can increase the cell division speed, thereby effectively increasing the growing speed at a wound, having an insecticidal effect on the wound and avoiding viable eggs left at the wound. The wound repairing agent can sterilize the wound, and wound infection is prevented especially by aid of killing of anaerobes in a wrapping process.

The invention belongs to the technical field of pesticide and particularly relates to a urea carbamate methyl substituted arly ester compound with bactericidal activity. The urea carbamate methyl replaced arly ester comprises N-methyl carbamate 4-(N-methyl-N'-arly ureido methyl) phenyl ester and N-methyl carbamate 2-(N-methyl-N'-arly ureido methyl) phenyl ester, and the constitutional formulas ofthe compound are respectively shown in a formula (I) and a formula (II). In the formula (I) and the formula (II), a benzene ring connected with an N atom has a substituent R, and the R can be H, 4-CH3, 4-CH3O, 4-Cl, 2-CH3, 2-CH3O, 2-Cl and 3-Cl. The compound can be applied to germ prevention and control of crops and is simple to synthesis, in addition, the used raw materials are easy to obtain.

The invention discloses an M15 methanol gasoline vapor pressure stabilizer, which is prepared from 18.0-31.0% of N-(3-aminopropyl)-N-methyl tert-butyl carbamate, 15.0-29.5% of 2-dimethylamino-2-methyl-1-propanol, 15.0-24.5% of 6-methyl-3,5-heptadiene-2-ketone, 13.0-24.0% of diethyl tert-butyl hosphonoacetate, 10.0-20.5% of 2,2,5,5-tetramethyl tetrahydrofuran, and 9.0-19.5% of 2,3-dimethylhexane in a mixing manner. The vapor pressure stabilizer disclosed by the invention is significant in effect of reducing the vapor pressure of the M15 methanol gasoline; 0.2-0.5% of vapor pressure stabilizer is added to common M15 methanol gasoline, so that the vapor pressure of the methanol gasoline accords with the requirements of GB17930-2013 'motor gasoline'.

The invention relates to a biomass derivative methyl furan-2,5-dimethyl carbamate and a preparation method thereof. The structural formula of the compound is shown in the specification. The preparation method comprises the following steps: adding 2,5-bis (aminomethyl) furan, dimethyl carbonate and a catalyst into an atmospheric-pressure or high-pressure reactor in an inert atmosphere, and reacting for 1-7 hours to obtain a product methyl furan-2,5-dimethyl carbamate; the catalyst is sodium methoxide or zinc acetate. The obtained substance can be used as an intermediate for modification and organic synthesis of pesticides, medicines and synthetic resin; the preparation method is green and safe and has a good application prospect.

The invention relates to the technical field of power pole towers, and concretely discloses a rat-bite-preventing special power pole tower formula, which is prepared from the following raw materials in parts by weight: 100 parts of SG resin, 2 to 4 parts of tribasic lead sulfate, 35 to 45 parts of nanometer calcium carbonate, 0.5 to 1.5 parts of dibasic lead phosphite, 1 to 2 parts of DOP, 1 to 3parts of epoxidized soybean oil, 1 to 2 parts of metallic soap, 1.5 to 2 parts of triphenyl phosphite, 0.2 to 0.6 part of triazine-5UV-9, 0.3 to 0.8 part of polyethylene wax, 2 to 4 parts of ACR, 4 to6 parts of CPE, 3 to 5 parts of calcium carbonate, 0.7 to 1.5 parts of capsaicine, 2 to 6 parts of O-isopropylphenyl methyl carbamate and 1 to 2 parts of 2-dimethyl cyclopropane carboxylate. The formula provided by the invention overcomes the defects in the prior art; rat-repelling ingredients prepared from the capsaicine, the O-isopropylphenyl methyl carbamate and the 2-dimethyl cyclopropane carboxylate are added; nontoxicity and harmlessness are realized; the environment pollution cannot occur; for the best advantage, rat repelling effects can be achieved; the plastic power pole tower is prevented from being bit by rats.

The invention discloses a preparation method of an isavuconazonium sulfate intermediate. The preparation method comprises the following steps: firstly, reacting absolute ethyl alcohol, sodium ethoxide and methylamine hydrochloride, cooling an obtained reaction solution, adding an ethanol solution of 1-chloroethyl methylcarbamate for continuous reaction, and conducting filtering to obtain an ethanol solution of methyl carbamic acid-1-chloroethyl ester; cooling the obtained solution, adding an ethanol solution of 2-chloro-3-pyridinemethanol for stirring reaction, filtering a reactant, removing ethanol, adding dichloromethane for dissolving, conducting washing after dissolving, and taking an organic phase, namely a dichloromethane solution of 1-chloro-ethyl (3-hydroxymethyl-pyridin-2-yl)-methylcarbamate; and firstly adding BOC-sarcosine into the obtained solution, then adding carbodiimide and 4-dimethylaminopyridine in batches for a reaction, and performing treatment after the reaction, so as to obtain the isavuconazole onium sulfate intermediate. The isavuconazonium sulfate is prepared by using the technical scheme of the invention, the side reaction of the process is less, and the purity of the obtained product is high.

A novel compound and method for preventing or treating neurodegenerative diseases by inhibiting acetylcholinesterase and binding the sigma-1 receptor are disclosed. Dimethylcarbamic acid 2,3-bis-dimethylcarbamoyloxy-6-[4-(4-ethyl-piperazin-yl)-butyryl]-phenyl ester and its derivatives represent a novel therapeutic strategy against β-amyloid peptide induced neurotoxicity, in inhibiting acetylcholinesterase, in improving cholinergic transmission, in binding the sigma-1 receptor, and in releasing a metabolite that is active both as a sigma-1 receptor ligand and an antioxidant.

The invention discloses a method for synthesizing N-methyl carbamate, and relates to the technical field of chemical synthesis of fine chemical products. The method comprises the following steps: in an atmosphere with nitrogen in a reaction kettle, mixing urea and excessive methanol to react, after the reaction is finished, performing cooling, relieving pressure, removing reactants, recovering methanol, performing distilling, collecting a distillation section at 167-168 DEG C, and obtaining the Nmethyl carbamate. The method has the advantages of high conversion rate, accessible raw materials,simple flow, high raw material conversion rate, favorable product selectivity and favorable commercial value of byproducts, and does not use any catalyst in the preparation process, thereby reducing the trouble of the subsequent separation procedure and enhancing the production safety.

A process for manufacturing 2-isobutyl-6-(3-(methylamino)azetidin-l-yl)pyrimidin-4-amine of Formula (I):

including starting from 6-chloro-2-isobutylpyrimidin-4-amine and tert-butyl azetidin-3-yl(methyl)carbamate, or another N-protected N-methylazetidin-3-amine, and performing the following steps: (a) coupling reaction of both compounds in dimethylsulfoxide in presence of potassium carbonate to afford an intermediate protected compound; and (b) deprotection of the protected compound to afford 2-isobutyl-6-(3-(methylamino)azetidin-1-yl)pyrimidin-4-amine. Also, a process for manufacturing the intermediate protected compound, wherein deprotection step (b) is omitted, and the compounds obtained from the processes.

The invention discloses a pesticide mixture capable of attracting insect pests. Raw materials comprise the following components in parts by weight: 15-35 parts of dimethylcarbamate, 10-20 parts of amino oligosaccharin, 8-12 parts of pyrophosphate, 5-7 parts of fludioxonil, 10-20 parts of honey, 8-12 parts of sodium lignin sulfonate, 1-3 parts of hydroxymethyl cellulose, 4-6 parts of xanthan gum and 8-12 parts of tartaric acid. The pesticide mixture disclosed by the invention has the advantages that different insect pests can be killed by virtue of combination of multiple effective insecticidal ingredients, and the insect pests are attracted under the action of honey inside, so that the insecticidal efficiency is improved.

The invention provides an avermectin emulsion preparation, and a preparation method and application thereof, and particularly provides a pesticide preparation. The pesticide preparation is prepared from the following components in percentage by weight: 0.1-10% of avermectin, 5-45% of an organic solvent, 5-20% of an emulsifier, 0.5-3% of a stabilizer, and water, specifically, the organic solvent comprises propylene glycol diacetate and methyl methyl-carbamate. The pesticide preparation has a good killing effect on pests, long-lasting effect, quick-acting effect, good repellent effect and killing effect on pests and has a wide insecticidal spectrum, and is convenient to use, low in cost, safe and reliable. The pesticide preparation has the characteristics of high efficiency, low toxicity andlow pesticide cost.

The invention belongs to the field of pharmaceutical chemicals, and particularly relates to an ivabradine intermediate compound IV. The method for preparing the ivabradine intermediate compound IV comprises the steps of dissolving 7, 8-dimethoxy-1, 3, 4, 5-tetrahydro-benzazepin-2-one in an organic solvent, adding alkali, stirring, and dropwise adding (3-chlorine-propyl)-methyl-tert-butyl carbamate into the obtained solution to obtain the compound IV. The invention provides a novel intermediate compound IV of ivabradine, and provides a novel method for simply and efficiently preparing ivabradine by using the compound, and the whole synthesis method is simple and convenient to operate, high in reaction yield, high in purity of the obtained product, and more suitable for industrial production.