44 results about "Phenylmethanol" patented technology

The invention discloses a polysilsesquioxane / polyether-ether-ketone composite membrane, a preparation method thereof and application of the polysilsesquioxane / polyether-ether-ketone composite membrane in organic mixed solvent separation, and aims to solve the problem of large-area deposition of a defect-free polysilsesquioxane hybrid membrane on a polymer substrate in the prior art. According to the present invention, the 1, 2-bis (triethoxysilyl) ethane polysilsesquioxane precursor is adopted as the raw material to prepare the membrane material, the new membrane preparation method is provided, the processing process is designed and optimized from the aspects of the simplicity and convenience of the membrane preparation process, the industrialization of the membrane separation technology, the improvement of the membrane preparation efficiency and the like, the membrane preparation efficiency is improved, and the certain separation performance is provided; the method has an excellent effect on separation and recovery of methanol / toluene and methanol / dimethyl carbonate.

The invention discloses a method for detecting related substances in imaric acid dihydrochloride by HPLC (High Performance Liquid Chromatography), and belongs to the technical field of chemical engineering and pharmacy, the related substances in the imaric acid dihydrochloride are detected by high performance liquid chromatography, a phosphate buffer solution (0.05 mol / L of monopotassium phosphate solution, and pH adjusted to 2.5 by phosphoric acid) is used as a mobile phase A, acetonitrile is used as a mobile phase B, gradient elution is carried out, the flow rate is 1.0 ml / min, the detection wavelength is 250nm, and the detection wavelength is 250nm. The column temperature is 40 DEG C, and the detection wavelength is 235nm; the method can be used for effectively separating and quantitatively detecting imatamide, demethylated imaric acid dihydrochloride, ortho-imaric acid, meta-imaric acid, p-hydroxymethyl benzamide, an intermediate B, p-hydroxymethyl benzoic acid, an imaric acid dimer, p-cyanobenzyl alcohol, p-chloromethyl benzamide, p-toluic acid and p-chloromethyl benzoic acid in the imaric acid dihydrochloride. The method disclosed by the invention is simple and convenient to operate, strong in specificity, high in sensitivity and accuracy, good in linearity and capable of effectively controlling the quality of a p-imaric acid dihydrochloride product.

The present application relates to the technical field of plastic processing aids, and specifically discloses a method for preparing a PVC processing aid. A method for preparing a PVC processing aid, based on elaiophyllic acid, introduces a rigid benzene ring structure through esterification with benzyl alcohol, introduces a ketal and an ester structure through reaction with ethyl levulinate, then reacts with palmitoleic acid to introduce a double bond, and forms an epoxy structure through cyclization with m-chlorobenzene peroxyformic acid, and finally prepares a PVC processing aid, and the prepared PVC processing aid has higher plasticity, lower volatility and lower mobility. In addition, the PVC processing aid of the present application uses biomass renewable resources as raw materials, is non-toxic and harmless, and is environmentally friendly.

The invention relates to the field of organic synthesis, and discloses a preparation method of bifenthrin. The method comprises the following steps: in the presence of a catalyst composition, enabling kung-fu acid and 2-methyl-3-phenylbenzyl alcohol to be in contact for esterification reaction, the catalyst composition comprises a component A and a component B, wherein the component A is selected from an oxyacid ester of an IVB group element and / or a compound formed by the IVB group element and alcohol; wherein the component B is selected from at least one of inorganic salt of copper, oxide of copper, oxide of tin and inorganic salt of tin. The yield of the bifenthrin prepared by the method is high (more than 98%), the purity is high (up to 99.4%), the produced bifenthrin isomers are less (less than 0.5%), the market requirements can be met, and the whole process flow is efficient and environment-friendly.

The invention discloses a method for preparing a chiral benzhydrol compound through asymmetric hydrogenation of o-amido benzophenone under catalysis of rhodium. The chiral rhodium catalyst is generated in situ from a metal rhodium salt and a chiral phosphine-phosphoramidite ligand in various solvents. Compared with other methods for synthesizing chiral benzhydrol, the method has the characteristics of cheap catalyst, easiness in preparation of chiral ligand, mild reaction conditions, simplicity and convenience in operation, high yield, high enantioselectivity and the like, and can be applied to large-scale preparation of chiral benzhydrol compounds. The method is also suitable for efficient preparation of the rice plant growth regulation inhibitor (S)-Inabenide, the yield can reach 92%, the enantioselectivity can reach 96%, and the method has good industrial application prospects.

The present invention provides an electrochromic material, preparation method, and application for monitoring battery health. Taking the total mass fraction as 100%, the electrochromic material comprises ethoxylated bisphenol A dimethacrylate, tripropylene glycol diacrylate, isobornyl methacrylate, 4-diphenylmethanol methacrylate, 4-acryloylmorpholine, an antioxidant, a photoinitiator, and an electrochromic polymer, wherein the electrochromic polymer is a metal complex of a pyridine derivative. The electrochromic polymer provided by the present invention can rapidly react under the action of light or electricity, causing the color of the material to change from transparent to colored. This allows for continuous monitoring of battery leakage, enabling timely detection of battery leakage problems through electrochromism and prompt replacement of problematic battery modules, thereby facilitating maintenance and servicing of battery equipment.

The present invention relates to the technical field of chemical synthesis, and provides a 4-biphenylmethanol synthesis method, which comprises: S1, uniformly mixing biphenyl, a solvent and a catalyst I, adding methyl chloroformate in an inert atmosphere, and carrying out a reaction to obtain 4-methyl bibenzoate; s2, mixing the methyl 4-bibenzoate, an alcoholic solution and a catalyst II, reacting, and recrystallizing to obtain the 4-biphenylcarbinol, a solution used during recrystallization in S2 comprises ethyl acetate. According to the technical scheme, the problems of low yield and low purity in the synthesis process of 4-biphenylcarbinol in related technologies are solved.

The application discloses a polysilsesquioxane / polyether ether ketone composite film, a preparation method thereof and application of the composite film in separation of organic mixed solvents, and aims at the problem of depositing a defect-free polysilsesquioxane hybrid film on a polymer substrate in a large area. A film material is prepared by taking 1,2-di(triethoxysilyl)ethane polysilsesquioxane precursor as raw material, a new film preparation method is provided, and the processing technology is designed and optimized from the aspects of simplicity of the film preparation technology, industrialization of the film separation technology and improvement of the film preparation efficiency. The film preparation efficiency is improved, and the film also has certain separation performance, and has excellent effects on separation and recovery of methanol / toluene and methanol / dimethyl carbonate.

A benzotriazole-modified anti-sagging resin, a preparation method therefor, and a coating. The raw materials of the modified anti-sagging resin, calculated by parts by weight, comprise the following components: 60-80 parts of a polymer resin; 5-20 parts of a solvent; 1-3 parts of one or more mixed diisocyanates; and 1-4 parts of benzotriazole containing a primary amine group. The preparation method comprises: S1: mixing a primary amine diphenylmethanol with a portion of the solvent, to prepare a primary amine diphenylmethanol solution of a preset concentration; S2: mixing the polymer resin and the remaining solvent uniformly in a reaction kettle with continuous stirring, maintaining the reaction system temperature at 0-40°C, dispersing the primary amine diphenylmethanol solution prepared in step S1 into the reaction system, adding the diisocyanate(s), and stirring, to obtain the modified anti-sagging resin. By means of a benzotriazole-based UV absorber present in the form of polyurea crystals, the risk of volatilization and incompatibility with a coating are avoided, and this can also enhance the aging resistance of the anti-sagging resin.

The present invention relates to the field of packaging technology, and discloses an anti-deformation paper packaging box and a manufacturing process thereof. Modified tannic acid is prepared using tannic acid, undecylenyl chloride, and chloroprene rubber. The chloroprene rubber helps to improve heat resistance and weather resistance, and the long aliphatic carbon chain of undecylenyl chloride can have a toughening effect. An isocyanate-terminated prepolymer with good water resistance is prepared using polytetrahydrofuran diol and diphenylmethane diisocyanate as raw materials. The prepolymer is connected to the modified tannic acid using 2-mercaptobenzyl alcohol and a photoinitiator to obtain a base material, and then asphalt with good waterproof performance is added. The isocyanate groups in the base material can modify the asphalt, improving the mechanical strength, water resistance, and temperature sensitivity of the asphalt, ultimately producing a waterproof adhesive with good water resistance and good flexibility. The waterproof adhesive, PVC film, and corrugated cardboard are hot-pressed to obtain an anti-deformation cardboard. The packaging box prepared with the anti-deformation cardboard has good waterproofness and is not easy to deform.

The present invention belongs to the field of synthesis of pharmaceutical intermediates, and relates to a preparation method of biphenyl benzazole intermediate 4-(α-chlorobenzyl) biphenyl. 4-Phenyldiphenylmethanol is added to N,N-dimethylformamide, and thionyl chloride is added dropwise. After the addition is complete, the mixture is heated to room temperature to 80 °C for reaction. After the reaction is complete, water is added to the reaction material, and the temperature is lowered for crystallization. It is filtered, washed with water, and dried to obtain the product. The preparation method provided by the present invention is simple in operation, low in energy consumption, high in yield, good in purity, and suitable for large-scale industrial production.

The invention provides a preparation method of 2-amino-5-chlorobenzhydrol, and relates to the technical field of medicine synthesis. The method comprises the following steps: dissolving 5-chloro-3-phenyl-2, 1-benzisoxazole in ethanol, reacting with sodium borohydride under the catalytic action of nitrogen-doped porous graphene-silicon dioxide until the content of 2-amino-5-chlorobenzhydrol in a reaction solution detected by HPLC (High Performance Liquid Chromatography) is not lower than 93.5%, stopping the reaction, filtering, and collecting filtrate, thereby obtaining the 2-amino-5-chlorobenzhydrol. And carrying out reduced pressure distillation on the filtrate, cooling, recrystallizing, carrying out suction filtration, and drying to obtain the 2-amino-5-chlorobenzhydrol. According to the preparation method disclosed by the invention, the 2-amino-5-chlorobenzhydrol is synthesized in one step through direct reduction by a one-pot method, synthesis and separation of an intermediate are not needed, and the reaction process is remarkably shortened.

The invention is applicable to the technical field of antibiotic intermediate preparation, and provides an efficient and environment-friendly tazobactam enzymatic preparation process, tazobactam diphenylmethyl ester is used as a substrate, high-temperature-resistant lipase is used for catalysis, water is used as a solvent, reaction is performed at 40-100 DEG C, and the conversion rate is larger than or equal to 99.5%. And filtering and recovering enzyme while hot after reaction, wherein the recovery rate is greater than or equal to 95%. The product purity is greater than or equal to 99.5%, and the benzhydrol recovery rate is greater than or equal to 90%. Compared with an existing chemical method, the process is mild in reaction condition, environment-friendly and low in cost. The embodiment verifies the feasibility of the process, the advantages of the method are prominent in proportion, the industrialization prospect is wide, and remarkable economic and social benefits can be brought.

The glycol composition includes a glycol and a tocopherol blend including D-alpha tocopherol and one or more of D-beta tocopherol, D-gamma tocopherol, and D-delta tocopherol, wherein the D-alpha tocopherol is less than 50% by weight of the sum of the D-alpha tocopherol, D-beta tocopherol, D-gamma tocopherol, and D-delta tocopherol.

The invention relates to a nanoscale targeted health intervention nutritional ingredient embedding method, and belongs to the technical field of ingredient embedding. The specific embedding method comprises the following steps: preparing 1-[(tert-butoxy) methyl]-4-iodobenzene by utilizing iodobenzene methanol or tert-butyldimethylsilyl chloride solution; adding selenium powder, a first catalyst and alkali, and reacting to obtain 1-[(t-butoxy) methyl]-4-({4-[(t-butoxy) methyl] phenyl} disilyl) benzene; trifluoroacetic acid is added for a reaction, and bis (4, 1-hydroxy benzyl) diselenide is obtained; dissolving the mixed solution, EGCG and a second catalyst in an organic solvent to obtain a mixed solution containing EGCG; dropwise adding an oxalyl chloride solution into the mixed solution containing EGCG for reaction to obtain a SeOE polymer; the preparation method comprises the following steps: emulsifying and homogenizing a SeOE polymer solution and a polyvinyl alcohol solution, centrifuging and freeze-drying to obtain the SeOE polymer nanoparticles. According to the invention, by introducing an ROS sensitive chemical part, the ROS removal capability of the targeted delivery polymer and the oxidation stability of EGCG are improved.

This invention relates to the field of organic synthesis and discloses a method for preparing bifenthrin. The method includes: contacting kungfu acid and 2-methyl-3-phenylbenzyl alcohol in the presence of a catalyst composition to carry out an esterification reaction; wherein the catalyst composition includes component A and component B; wherein component A is selected from oxyacid esters of group IVB elements and / or compounds formed by group IVB elements and alcohols; wherein component B is selected from at least one of inorganic salts of copper, oxides of copper, oxides of tin, and inorganic salts of tin. The bifenthrin prepared by this method has a high yield (>98%), high purity (up to 99.4%), and produces fewer bifenthrin isomers (<0.5%), meeting market requirements. The entire process is highly efficient and environmentally friendly.

The invention provides a preparation process for co-production of methoxyamine hydrochloride and N, O-dimethyl hydroxylamine hydrochloride. Comprising the steps of aminolysis, methylation reaction, extraction separation, primary hydrolysis, distillation, dehydration and recrystallization of a first product, secondary hydrolysis, dehydration and recrystallization of a second product and the like. According to the invention, methoxyamine hydrochloride and N, O-dimethyl hydroxylamine hydrochloride can be prepared at the same time, and reaction conditions can be greatly widened, so that high-efficiency and high-yield production is realized, and meanwhile, the product purity is greatly improved; through the coproduction design, the equipment utilization rate is high, the cost is greatly reduced, the recovery rate of solution substances such as methyl acetate, dichloromethane, toluene, methanol and isopropanol is greater than or equal to 90%, the wastewater is circulated and zero discharged after being treated, only a small amount of common industrial waste salt is used as solid waste, the hazardous waste amount is greatly reduced, and the effect of environmental protection is achieved.

The application provides a cheap and simple method for regulating and controlling reduction products of photochemical reactions driven by plasmons at an interface, and belongs to the technical field of catalysis.The application can realize high selectivity and high efficiency of reduction of p-mercaptobenzoic acid (PMBA) molecules adsorbed on silver nanoparticles to generate thiophenol (TP), p-mercaptobenzaldehyde (PMBALD) or p-mercaptobenzyl alcohol (PMBALC) by adjusting excitation of localized surface plasmon resonance (LSPR) and the concentration of silver nitrate.In the method, the generation selectivity of TP, PMBALD or PMBALC is close to 100% by fine tuning the concentration of silver nitrate, and the generation selectivity of PMBALD or PMBALC is realized by regulating excitation power, excitation wavelength and excitation time of plasmon resonance (LSPR).

The present invention belongs to the field of chemical separation technology, and specifically relates to a method and system for continuously separating a mixture of chlorobenzene, methanol, and water. The method of the present invention comprises the following steps: S1. adding n-alkanes as entrainers to perform azeotropic distillation on the raw materials; obtaining a mixture of alkanes and methanol at the top of the tower, and obtaining a mixture of chlorobenzene, water, and methanol at the bottom of the tower; S2. phase-splitting the mixture of alkanes, methanol, and water obtained in step S1 to obtain an alkane phase and a methanol / alkane / water phase; distilling the methanol / alkane / water phase to obtain alkanes at the top of the tower, and obtaining a methanol and water mixture at the bottom of the tower; S3. distilling the methanol and water mixture obtained in step S2 to obtain a methanol product at the top of the tower; S4. phase-splitting the mixture of chlorobenzene, water, and alkanes obtained in step S1 to obtain a water phase and a chlorobenzene / alkane phase; distilling the chlorobenzene / alkane phase to obtain a chlorobenzene product at the bottom of the tower. The present invention achieves complete separation of the raw materials.

The invention belongs to the technical field of medicine refining and purification, and relates to a preparation method of medicinal bifonazole. The process comprises the following steps: reacting 4-phenyl benzhydrol with thionyl chloride and imidazole in a solvent toluene, adding water into the reaction liquid at high temperature, heating an organic phase, slowly adding acyl chloride, heating, stirring, cooling and crystallizing to obtain the bifonazole. The post-treatment process is simple, in the obtained product, the content of imidazole and isomer impurities and dimer impurities generated by reaction is 0.1% or below, the content of other single impurities is smaller than 0.1%, and the purity of the product is higher than 99%. The method has the advantages of low equipment requirement, low energy consumption and low production cost, and is suitable for large-scale production.

The present invention relates to a semi-aromatic polyamide material and a preparation method thereof, belonging to the technical field of materials. The semi-aromatic polyamide material is a PA6Z resin, which is insoluble in organic solvents such as formic acid, toluene, methanol, chloroform, tetrachloromethane, N,N-dimethylformamide, dimethyl sulfoxide and pyridine; the semi-aromatic polyamide material has a water absorption rate of 0.2-0.3%, a linear expansion coefficient of 10-14 ppm / °C, a melt index of 40-80 g / 10 min, an initial degradation temperature of 450-460°C, a heat deformation temperature of 200-300°C, a tensile strength of 50-60 MPa, an elongation at break of 3.3-4.5%, a flexural strength of 98-106 MPa, a flexural modulus of 2400-3600 MPa, and an impact strength of 5.8-7.6 KJ / m 2 The preparation method comprises: first, reacting 6Q monomer and terephthalic acid as raw materials to obtain PA6Q salt; then, mixing hexamethylenediamine, terephthalic acid, and PA6Q salt, and sequentially subjecting them to prepolymerization and polycondensation reactions to produce PA6Z resin. The product of the present invention combines high mechanical properties, thermal stability, low water absorption, and high dimensional stability; the preparation method is simple, safe, and reliable.

The present invention provides a method for synthesizing chiral 2-acylaminodiphenylmethanol. Using 2-acylaminobenzophenone as the raw material, a complex formed by iridium metal and a PNN ligand with a phenyl skeleton as the catalyst, and methanol as the solvent, a hydrogenation reaction occurs in this homogeneous catalytic system to obtain chiral 2-acylaminodiphenylmethanol with a high yield (>99%) and a high ee value (99%). This reaction has high activity, mild reaction conditions, and the starting materials are cheap and easily available, and has high industrial application value.

Described herein are compositions and methods that modulate or enhance the taste perceptions of a subject. Aspects of the present disclosure relate to compositions and methods of use comprising a flavonolignan, a steroid saponin, an iridoid glycoside, amentoflavone, a polyisoprenylated benzophenone, a phenylpropanoid, a pheylethanol derivate, a glycoside and / or analogs thereof (for example, a glycosylation molecule of an aglycone, an aglycone of a glycosylated molecule, or a further glycosylated molecule of a glycosylated molecule) obtained from a plant extract such as a Silybum marianum (milk thistle) extract, an Asparagus racemosus extract, a Smilax china extract, a Rehmannia glutinosa root extract, a Selaginella tamariscina extract, a Garcinia indicia extract, a Garcinia cambogia extract, a Trigonella foenum graecum L. extract, a Rhodiola rosea root or rhizome extract and / or other plant sources which are used for enhancing a subject's taste perception of sweetness, mouthfeel, astringency, bitterness, alcohol, carbonation, spice, salt, sourness, umami, tingling, numbing or cooling, harshness, pungency, burning, freshness, ripeness, juiciness, for increasing the amount of carbonation bubbles or decreasing the carbonation bubble size of a carbonated beverage, or for masking off-tastes

The invention discloses a preparation method of bromodiphenylmethane, and belongs to the technical field of organic synthesis.The preparation method comprises the steps that methylbenzene, hydrobromic acid and benzhydrol are mixed, then sodium bromide is added, then heating reflux reaction, standing liquid separation and refined petroleum ether treatment are conducted, cooling crystallization is conducted, and bromodiphenylmethane is obtained. The invention provides a preparation method of diphenylbromomethane, which is stable in process, safe to operate, environment-friendly and economical in cost. The method successfully solves the common problems of poor atom economy, low reaction selectivity, complicated post-treatment, difficulty in product purification and the like in the traditional bromination process by optimizing the raw material ratio and synergistic effect, accurately controlling the reaction process and adopting an original efficient purification process. The whole process from reaction to purification is optimized, and the method is particularly suitable for industrial production and has remarkable comprehensive benefits.

An aerosol generating material comprising at least two non-tobacco botanical materials, the aerosol generating material produces an aerosol when heated, the aerosol comprising: a first compound selected from the list consisting of: 2-methoxy- phenol, 2-methoxy-4-vinylphenol, vanillin, benzeneacetic acid, phenylethyl alcohol, maltol, and combinations thereof; and a second compound selected from the list consisting of: D-limonene, alpha-terpineol, levomenthol, menthol, 3-methyl butanoic acid, 2-methoxy phenol, terpinene-4-ol, 6-methyl-5-hepten-2-one, 1H-pyrrole-2- carboxaldehyde, alpha-methyl-benzenemethanol, theobromine, octadecanoic acid, n- hexadecanoic acid, methyl-ester-hexadecanoic acid, butyrolactone, caffeine, 9- octadecenoic acid, furfural, 2-methyl butanoic acid, 2,3-dihydrobenzofuran, 2- heptadecanone, and combinations thereof.

This invention discloses a method for synthesizing bifonazole, belonging to the field of pharmaceutical synthesis technology. The method uses 4-phenyldibenzyl alcohol and imidazole as raw materials, and phosphorus tribromide, phosphorus trichloride, or phosphorus oxychloride as condensing agents, to directly condense bifonazole in a solvent. The reaction conditions are mild, can be carried out at room temperature, the reaction is complete with few impurities, and the yield is high; it has low equipment requirements and is suitable for large-scale production.

To provide a conductive particle with lower connection resistance and higher connection reliability than ever before.SOLUTION: A conductive particle manufacturing method for forming a conductive layer on a surface of a core material particle by electroless plating, has a step of adding a sulfur compound to an electroless plating reaction solution during forming the conductive layer. It is preferable that the sulfur compound is at least one kind selected from a group consisting of 2-mercaptobenzothiazole, 2-mercaptobenzoxazole and 2-mercaptobenzimidazol.SELECTED DRAWING: Figure 1

The invention discloses a method for increasing the yield of xylene through methylation of toluene and methanol. The method comprises the following steps: (1) mixing toluene and methanol, feeding the mixture into a first reaction zone, contacting the mixture with an aromatic methylation catalyst in the presence of hydrogen, and carrying out a gas-phase methylation reaction to obtain a first material flow; and (2) introducing the first material flow into a second reaction zone, contacting the first material flow with a methyl transfer catalyst in the presence of hydrogen, obtaining a second material flow through a liquid-phase methyl transfer reaction, and separating to obtain a xylene product. The method provided by the invention can improve the selectivity of xylene and the conversion rate of toluene.

The application discloses a PtZn-ZnO catalyst rich in low-potential benzene acid production x The application discloses a catalyst with a PtZn intermetallic compound structure and rich in PtZn-ZnO interface active sites, and a preparation method and application thereof. x The catalyst can significantly promote the oxidation efficiency of biomass-derived alcohol organic small molecules at a low potential (<0.9 V, relative to a reversible hydrogen electrode). x The PtZn-ZnO catalyst is applied to an electrocatalytic benzene methanol oxidation reaction, and benzene methanol can be electrocatalytically oxidized into benzene acid at a low potential of 0.725 V with a selectivity of 99.5%, and the electrocatalytic Faraday efficiency can reach 100%, and the catalyst has high conversion efficiency and excellent product selectivity.