Medicine composition for inhibiting ovarian carcinoma cells

A technology of ovarian cancer cells and composition, applied in the field of biomedicine, can solve problems such as large toxic and side effects
CN109498618AInactive Publication Date: 2019-03-22ZUNYI MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZUNYI MEDICAL UNIVERSITY
Publication Date
2019-03-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a medicine composition for inhibiting ovarian carcinoma cells, and belongs to the technical field of the biological medicine. The composition is formed by combining 200ng / mL ofbrefeldin A (BFA) and 4.0-5.0microgram / mL of cisplatin (CDDP). The medicine composition can obviously inhibit the growth proliferation of the ovarian carcinoma cells and accelerate the apoptosis of the ovarian carcinoma cells, has a function of adjusting genes and protein related to the apoptosis of the ovarian carcinoma cells, is obvious superior to the individual medication, and has the effectof synergistically resisting the ovarian carcinoma cells. The medicine composition can be used as a target medicine composition for regulating and controlling the apoptosis pathway of the ovarian carcinoma cells, thereby providing a new comprehensive treatment strategy for the ovarian carcinoma clinically.
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Description

technical field

[0001] The invention relates to the technical field of biomedicine, in particular to a pharmaceutical composition for inhibiting ovarian cancer cells. Background technique

[0002] Cancer is a major disease that seriously threatens human survival and social development. Among them, ovarian cancer (ovarian carcinoma) is one of the three most common malignant tumors in women, and its incidence rate ranks third, after breast cancer and cervical cancer. However, because the ovary is located in the deep part of the pelvic cavity, early lesions are not easy to be found. Once symptoms appear, most of them are late. Therefore, its mortality rate ranks first in gynecological tumors.

[0003] The current clinical treatment of ovarian cancer is a combination of surgery and chemotherapy. Chemotherapy can be used alone in the palliative treatment of advanced cancer, or as a part of comprehensive treatment, combined with surgery, radiotherapy, etc. Chemotherapy can preve...

Claims

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