109 results about "Combined modality treatment" patented technology

The methods described herein provide reduction of intraocular pressure by administering a sustained release formulation including latanoprost and a pharmaceutically acceptable vehicle and administering an eye drop adjunctive composition to the eye of a patient. The sustained release formulation can release latanoprost continuously for at least 90 days from a punctum plug delivery system. The eye drop adjunctive composition can also include latanoprost.

Formulations for and methods of treatment of Dravet syndrome that avoid side effects are disclosed. The formulations comprise a 5-HT receptor agonists which does not agonize selected 5-HT receptor subtypes, and in particular does not agonize the receptor subtype 5-HT2B. Also disclosed are combinations of such 5-HT receptor agonists. Also disclosed are combinations of such 5-HT receptor agonists and SSRIs, SNRIs, and triptans for treating co-morbidities associated with Dravet syndrome.

The present technology relates to a method of treating cancer by sensitizing human tumours to DNA damaging therapies through activating FBXO32 expression. Transactivation of FBXO32 through the inhibition of EZH2, a histone methyltransferase, decreases p21 protein induction which results in the sensitization of human tumours to chemotherapy. The method further provides a prognostic method to determine if a combination treatment would be effective.

A combination for use in the treatment of pancreatic cancer comprising:(i) an anti-gastrin effective immunogenic composition; and,(ii) one or more chemotherapeutic agents suitable for inhibiting cancer growth.

The invention relates to the field of bioengineering and tumor markers, in particular to a marker for locally advanced esophageal squamous cell carcinoma prognosis and an application of the marker. The marker is a combined marker consisting of one or more of miR-135b-5p, miR-139-5p, miR-29c-5p and miR-338-3p, and locally advanced esophageal squamous cell carcinoma prognosis is predicted by detecting expression levels of the four miRNA in tumor tissue and performing calculation according to a formula (0.4690*miR-135b-5p expression level)+(0.3839*miR-139-5p expression level)+(0.1733*miR-29c-5p expression level)+(0.3368*miR-338-3p expression level). The combined marker has the advantages of good stability and high sensitivity and specificity and can more accurately and more valuably evaluateprognosis of patients than traditional clinical pathological factors such as TNM (tumor-node-metastasis) staging and the like. On one hand, the molecular marker related to esophageal squamous cell carcinoma prognosis is provided, on the other hand, an esophageal squamous cell carcinoma prognosis prediction model is established, so that individual treatment of esophageal squamous cell carcinoma isrealized, the comprehensive treatment level of the esophageal squamous cell carcinoma is improved, the life quality of esophageal squamous cell carcinoma patients is improved, and the lifetime of theesophageal squamous cell carcinoma patients is prolonged.

The invention discloses comprehensive treatment technology of ficus root rot, belonging to the technical field of tree protection. The technology mainly comprises the following parts: 1. root rot germ eradication and ficus disease treatment, specially, soil change and sterilization, disease root treatment and trunk cleaning; 2. new root growth promotion and feeding, specially, root promotion on the trunk base, utilization of ficus aerial root and young tree approach grafting; and 3. auxiliary measures, specially, branch cutting and burden alleviation, surrounding pathogen cleaning and regular coating of bactericides on the trunk. The technology has the main characteristics of good treatment effect and strong operability and has the following beneficial effects: the used drugs and articles have low cost and are easy to buy; the defect that the present conventional control methods have poor effects is made up; and the technology is suitable for rehabilitation of big ficus which has suffered from root rot.

The present invention relates to the combined treatment of pancreatic cancers, especially in patients with metastasis and in patients whose cancer is developing resistance to first line treatment with gemcitabine, comprising administration of masitinib and gemcitabine, both in appropriate dosage regimens allowing resensitisation of cancer cells to gemcitabine.

The invention discloses an application of an NK cell stock solution in preparation of a medicine for treating skin diseases. An NK cell is an important immune cell for an organism, and not only is related to tumor resistance, viral infection resistance and immune regulation, but also takes part in happening of hypersensitive responses and autoimmune diseases in some cases. The NK cell stock solution contains main components of NK cell excreted proteins and cell factors, including MIP-1alpha, MIP-1beta, RANTES, monocyte chemoattractant proteins, interleukin, colony stimulating factors, tumor necrosis factors, interferon and perforin, and these proteins and cell factors can be absorbed by the skin and directly act on target cells to kill or inhibit pathogenic microorganisms including bacteria, fungi, viruses and the like, improve an immune system of the skin, repair the damaged skin, and achieve an aim of comprehensively treating various skin diseases; and after the use of the NK cell stock solution, a protective film is formed on the surface of the skin, which is beneficial for rapid repair of the damaged skin and prevention of repeated aggravation of an illness.

The invention discloses a Chinese medicine for treating mammary gland foliole proliferation. The purpose of the invention is to provide the Chinese medicine for treating mammary gland foliole proliferation, which has advantages of fast phyma dissipation, difficult relapse and good curative effect. The medicine decoction is decocted by water with the bulk drugs according to the following weight ratio: 9 to 12 parts of semiaquilegia root, 10 to 20 parts of colter straw, 9 to 12 parts of wild chrysanthemum flower, 10 to 20 parts of honeysuckle flower, 20 to 40 parts of dandelion, 9 to 12 parts of folium citrus reticulatae and 6 to 10 parts of flower bud of Japanese apricot. The present invention has the advantages that the Chinese medicine for treating mammary gland foliole proliferation hasfunctions of clearing heat and detoxifying, detumescence and dissipating binds, coursing the liver and rectifying qi. The medicinal materials can be collected in the south of China. The invention uses a plurality of Chinese herbal medicines for a comprehensive treatment, which has the merits of obvious effect and convenient medicine taking, and the components conform to pharmaceutical administration specifications and have no toxicity or side effect on human bodies.

The invention relates to an external-use ointment for treatment of dermatopathy. The ointment is prepared by mixing and blending the following medicines (by weight): 6-9 parts of sulfamethoxazole, 5-8 parts of chloramphenicol, 5-8 parts of prednisone, 3-5 parts of borneol, 0-8 parts of sulfur flour, 5-8 parts of vitamin E, 4-8 parts of vitamin complex B, 6-10 parts of VC, 5-7 parts of B1, 0.01-0.04 part of triamcinolone acetonide, 10 parts of urea ointment, 30 parts of a Chinese herbal antibacterial paste, 8-10 parts of chlorpheniramine, 4-8 parts of chloramphenicol raw powder, 6-10 parts of metronidazole, 10 parts of B6 ointment, 0-15 parts of terbinafine hydrochloride emulsifiable paste and 0-10 parts of ketoconazole emulsifiable paste. The ointment of the invention is used for treatment of skin diseases such as dermatitis, eczema, acne, yellow fluid ulcers, manus and tinea pedis, psoriasis, etc., can be used for realizing antibiosis, anti-inflammation, itching-relieving and antiallergic functions and the function of boosting body immunity, reduces exudation and inflammatory response and promotes inflammatory resorption of wounds and growth of granulation tissues, and has a good comprehensive treatment effect.