109 results about "Combined modality treatment" patented technology

Methods for the treatment of sepsis with complement inhibitors are disclosed. In particular, C3 inhibitors, such as Compstatin and Compstatin analogs, are administered at various times following the onset of sepsis to alleviate tissue damage and organ failure, which are hallmarks of the second, extravascular stage of sepsis. Combination therapies for comprehensive treatment of sepsis are also disclosed. Pharmaceutical compositions and kits for use in the methods are disclosed as well.

The methods described herein provide reduction of intraocular pressure by administering a sustained release formulation including latanoprost and a pharmaceutically acceptable vehicle and administering an eye drop adjunctive composition to the eye of a patient. The sustained release formulation can release latanoprost continuously for at least 90 days from a punctum plug delivery system. The eye drop adjunctive composition can also include latanoprost.

The invention relates to the field of biology, in particular to MSC (mesenchymal stem cell) injection as well as a preparation and an application thereof. The injection comprises MSCs and a cell cryopreservation solution, wherein the cryopreservation solution comprises components in percentage by volume as follows: 25%-70% of an electrolyte balance solution, 5%-20% of clinical-grade DMSO (dimethyl sulfoxide), 1%-50% of 20% human serum albumin, 1%-10% of hydroxyethyl starch 130 / 0.4 and 5%-20% of triphosadenine-disodium magnesium chloride freeze-drying powder. The injection is free of animal serum, has clear ingredients and good cell cryopreservation effect and is safe and controllable, long-term storage and long-distance transport are facilitated, the survival rate of cells after recovery is higher than 95%, the vitality is high, and the injection can effectively relieve injury and inflammation symptoms of lesion tissue of lungs and promote tissue regeneration of the lungs, so that acute lung injury can be fundamentally and comprehensively treated.

Formulations for and methods of treatment of Dravet syndrome that avoid side effects are disclosed. The formulations comprise a 5-HT receptor agonists which does not agonize selected 5-HT receptor subtypes, and in particular does not agonize the receptor subtype 5-HT2B. Also disclosed are combinations of such 5-HT receptor agonists. Also disclosed are combinations of such 5-HT receptor agonists and SSRIs, SNRIs, and triptans for treating co-morbidities associated with Dravet syndrome.

The present technology relates to a method of treating cancer by sensitizing human tumours to DNA damaging therapies through activating FBXO32 expression. Transactivation of FBXO32 through the inhibition of EZH2, a histone methyltransferase, decreases p21 protein induction which results in the sensitization of human tumours to chemotherapy. The method further provides a prognostic method to determine if a combination treatment would be effective.

A combination for use in the treatment of pancreatic cancer comprising: (i) an anti-gastrin effective immunogenic composition; and, (ii) one or more chemotherapeutic agents suitable for inhibiting cancer growth.

The invention provides an NSCLC patient postoperative short-period recurrence metastasis risk evaluating system which comprises a preprocessing module, a characteristic extracting module, an AI network cluster risk evaluating module and an ANFIS network integrated risk evaluating module. The preprocessing module is used for collecting and preprocessing multidimensional patient clinical data. The multidimensional patient clinical data comprise patient preoperative CT radiomics data, tumor histopathology data and tumor clinical. The characteristic extracting module is used for extracting the characteristic of the data sample after preprocessing. The AI network cluster risk evaluating module is used for performing recurrence risk probability evaluation on the extracted sample characteristic.The ANFIS network integrated risk evaluating module is used for using a recurrence risk probability evaluation result as an input characteristic vector, establishes an ANFIS network, uses a recurrence / metastasis risk quantification probability and dangerous degree as the output, and performs final integrated risk evaluation. The system can supply a reference for selecting a radial curing postoperative comprehensive treatment plan by a lung cancer patient and has high predicting accuracy.

The invention discloses a rheumatism preparation used for treating rheumatism, mainly solving the technical problems of treating both principal and secondary aspects of rheumatism, especially rheumatism arthritis, and causing rheumatism to be difficult to relapse after healing. The rheumatism preparation comprises the following components in parts by weight: 1-5000 parts of ants, 1-30 parts of scorpions, 1-500 parts of centipedes, 5-500 parts of radix astragali, 1-1000 parts of salvia miltiorrhiza, 1-300 parts of cortex acanthopanacis, 1-100 parts of tree peony bark and 1-100 parts of szechuan lovage rhizome. Compared with the prior art, the rheumatism preparation has the functions of tonifying liver and kidney, strengthening muscles and bones, replenishing qi and blood, expelling wind and removing dampness, reducing phlegm and removing blood stasis as well as dredging collaterals and relieving pain. While remaining all the active ingredients and active substances of the ant raw material, the preparation provided by the invention is directly absorbed and utilized by the human bodies in the form of enzyme, so that the absorption and utilization ratio is improved to more than 80% from 20%, and the preparation bidirectionally regulates the immunity, strengthens body resistance to eliminate pathogenic factors and simultaneously treats different diseases, thus radically achieving the aim of comprehensively treating rheumatism.

The invention discloses a medicament for treating geriatric disease, and at the medicament can be used for solving the technical problems of improving the functions of viscera, improving the immunity, invigorating qi and blood, and ensuring not to cause the body of middle-aged and aged people aiming at the geriatric disease. The technical scheme adopted by the invention is as follows: the medicament is characterized by comprising 1 to 5,000g of ants, 1 to 3,000g of glssy ganoderma, and 1 to 500g of pearl. Compared with the prior art, the unique broad-spectrum and immunity dual immunomodulatory action of ants are sufficiently played, the degraded thymus gland is promoted to proliferate, the weight is increased, the lymphocytes in the cortical area are increased, the functions of immunity center are activated, the leucocytes and lysozymes in the blood are increased, and the phagocytosis is improved. The medicament has the functions of nourishing kidney, tonifying spleen and dredging abdomen, tranquilizing by nourishing the heart and promoting blood circulation to remove meridian obstruction, so that the body is restored to a normal metabolizing state to comprehensively treat the geriatric disease. Therefore, the medicament achieves the aims of preventing and treating geriatric disease, delaying aging, improving wisdom and strengthening body, and protecting bodies of middle-aged and aged people from being hurt.

A combination therapy for the treatment of acute myocardial infarction comprises administering a combination of a thrombolytic agent and levosimendan or a pharmaceutically acceptable salt thereof to a patient. The combination synergistically reduces mortality of patients with acute myocardial infarction.

The invention relates to the field of bioengineering and tumor markers, in particular to a marker for locally advanced esophageal squamous cell carcinoma prognosis and an application of the marker. The marker is a combined marker consisting of one or more of miR-135b-5p, miR-139-5p, miR-29c-5p and miR-338-3p, and locally advanced esophageal squamous cell carcinoma prognosis is predicted by detecting expression levels of the four miRNA in tumor tissue and performing calculation according to a formula (0.4690*miR-135b-5p expression level)+(0.3839*miR-139-5p expression level)+(0.1733*miR-29c-5p expression level)+(0.3368*miR-338-3p expression level). The combined marker has the advantages of good stability and high sensitivity and specificity and can more accurately and more valuably evaluateprognosis of patients than traditional clinical pathological factors such as TNM (tumor-node-metastasis) staging and the like. On one hand, the molecular marker related to esophageal squamous cell carcinoma prognosis is provided, on the other hand, an esophageal squamous cell carcinoma prognosis prediction model is established, so that individual treatment of esophageal squamous cell carcinoma isrealized, the comprehensive treatment level of the esophageal squamous cell carcinoma is improved, the life quality of esophageal squamous cell carcinoma patients is improved, and the lifetime of theesophageal squamous cell carcinoma patients is prolonged.

The invention discloses comprehensive treatment technology of ficus root rot, belonging to the technical field of tree protection. The technology mainly comprises the following parts: 1. root rot germ eradication and ficus disease treatment, specially, soil change and sterilization, disease root treatment and trunk cleaning; 2. new root growth promotion and feeding, specially, root promotion on the trunk base, utilization of ficus aerial root and young tree approach grafting; and 3. auxiliary measures, specially, branch cutting and burden alleviation, surrounding pathogen cleaning and regular coating of bactericides on the trunk. The technology has the main characteristics of good treatment effect and strong operability and has the following beneficial effects: the used drugs and articles have low cost and are easy to buy; the defect that the present conventional control methods have poor effects is made up; and the technology is suitable for rehabilitation of big ficus which has suffered from root rot.

The invention relates to a method of treating erythema and / or telangiectasia associated with rosacea in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the site of erythema and / or telangiectasia on the skin of the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier.

The present invention relates to a prostatic comprehensive therapeutic equipment. Said prostatic comprehensive therapeutic equipment includes the following several portions: microcomputer controller, comprehensive therapeutic head, printing machine, music and video playback device. Besides, said invention also provides its working principle and concrete operation method.

The present invention relates to the combined treatment of pancreatic cancers, especially in patients with metastasis and in patients whose cancer is developing resistance to first line treatment with gemcitabine, comprising administration of masitinib and gemcitabine, both in appropriate dosage regimens allowing resensitisation of cancer cells to gemcitabine.

The invention relates to a self-service moxibustion treatment table which comprises a table body, moxibustion boxes, heaters, heater controllers, temperature sensors and a treatment controller. The self-service moxibustion treatment table has the advantages that corresponding acupuncture points can be fumigated by the moxibustion boxes in a concentrated manner, accordingly, disease treatment effects of artemisia vulgaris can be realized to the greatest extent, and the shortcoming of low actual utilization efficiency due to artemisia vulgaris naked flame fumigation and gas volatilization of existing traditional moxibustion treatment methods and treatment equipment can be completely overcome; comprehensive treatment characteristics of traditional Chinese medicine can be sufficiently realized, the self-service moxibustion treatment table has moxibustion traditional Chinese medicine treatment characteristics and is combined with traditional techniques for fumigating soles by the aid of traditional Chinese medicines, comprehensive modern TDP (special electromagnetic wave) radiation heating moxibustion curative effects can be realized, accordingly, traditional Chinese medicine treatment principles of treating manifestation and root cause of diseases can be carried forwards, and excellent curative effects can be realized.

The invention relates to a tracking marker for the stereotactic radiation therapy (SRT). The tracking marker comprises a body. One end or the two ends of the body is / are provided with an identification body. The identification body is provided with a shape / structure that produces friction with a focus tissue, wherein the shape / structure can be in the form of a cylindrical / helically wound filiform texture with an external thread. According to the technical scheme of the invention, the tracking marker for the SRT is made of the MRI-sensitive polymer material. Meanwhile, the tracking marker is characterized in that one end or both ends of the body is / are provided with the identification body of a special-shaped structure, so that the tracking marker is higher in distinguishing degree in image after the implanting process. At the same time, the tracking marker is not easy to shift, so that the image positioning accuracy is improved. Finally, the comprehensive treatment effect of the precise radiation therapy is increased. Moreover, the tracking marker can be applied to the precise radiation therapy based on the MRI positioning mode.

The invention discloses an application of an NK cell stock solution in preparation of a medicine for treating skin diseases. An NK cell is an important immune cell for an organism, and not only is related to tumor resistance, viral infection resistance and immune regulation, but also takes part in happening of hypersensitive responses and autoimmune diseases in some cases. The NK cell stock solution contains main components of NK cell excreted proteins and cell factors, including MIP-1alpha, MIP-1beta, RANTES, monocyte chemoattractant proteins, interleukin, colony stimulating factors, tumor necrosis factors, interferon and perforin, and these proteins and cell factors can be absorbed by the skin and directly act on target cells to kill or inhibit pathogenic microorganisms including bacteria, fungi, viruses and the like, improve an immune system of the skin, repair the damaged skin, and achieve an aim of comprehensively treating various skin diseases; and after the use of the NK cell stock solution, a protective film is formed on the surface of the skin, which is beneficial for rapid repair of the damaged skin and prevention of repeated aggravation of an illness.

The invention relates to a traditional Chinese medicine compound preparation for reducing postoperative recurrence and metastasis of colorectal cancer and a preparation method of the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation is prepared from the following traditional Chinese medicine raw material medicines in parts by weight: 10-30 parts of codonopsis pilosula, 10-15 parts of poria cocos, 10-15 parts of rhizoma atractylodis macrocephalae, 10-15 parts of rhizoma smilacis glabrae, 10-30 parts of chinaroot greenbriers, 10-15 parts of fiveleaf akebia fruits, 5-15 parts of endothelium corneum gigeriae galli and 3-10 parts of pericarpium citri reticulatae. The traditional Chinese medicine compound preparation provided by the invention has the functions of invigorating spleen and supplementing qi and strengthening the body resistance and detoxifying, and comprehensively treats postoperative colorectal cancer, and reduces recurrence and metastasis of colorectal cancer, so that the preparation is low in cost, safe and effective and free from toxic and side effects, can reduce expression of serum VEGF (Vascular Endothelial Growth Factor), P53, COX-2 and survivin, and remarkably reduces metastasis of postoperative colorectal cancer and improves the living quality of the patient.

The invention discloses medical appliances, and particularly discloses a comprehensive treatment bed for burns and wounds. The comprehensive treatment bed comprises an elevator control device, a hydraulic elevator, an elevator control device console and a hinge box. The comprehensive treatment bed is characterized in that the hydraulic elevator is arranged in the comprehensive treatment bed body; the elevator control device is arranged at the upper end of the hydraulic elevator; the elevator control device console is arranged on one side of the hydraulic elevator; an upper bed board sleeving groove and a lower bed board sleeving groove are respectively formed in one end of an upper bed board movable bracket and one end of a lower bed board movable bracket; and protective plates are arranged at the one end of an upper bed board and one end of a lower bed board of the treatment bed. The comprehensive treatment bed is reasonable in design, has the beneficial effect of effectively controlling wound infection of a patient and helping doctors perform patient body turning, medicine application, soaking bathing and other treatment operations, so that the probability of patient infection can be reduced, and convenience is brought to treatment and rehabilitation of patients.

The invention relates to application of astragaloside IV in the preparation of drugs for treating and delaying intervertebral disc degeneration. Astragaloside IV serving as a plant extract with good biological activity has the advantages that the drug dosage is low and the anti-apoptotic effect on nucleus pulposus cells is obvious; compared with Western medicine, astragaloside IV serving as traditional Chinese medicine is mild in anti-apoptotic effect, and an alternative treatment drug can be provided for the comprehensive treatment of intervertebral disc degeneration diseases.

The present invention relates to a combination treatment for hematological cancers. More specifically; a combination of a telomerase inhibitor and a Bcl-2 inhibitor are useful in treating hematological cancers, including AML. In certain embodiments, the telomerase inhibitor is imetelstat or imetelstat sodium and the Bcl-2 inhibitor is ABT-199.

The multifunctional cervical spondylopathy and lumbar vertebrae disease therapeutic equipment is a comprehensive therapeutic equipment integrating neodymium-iron-boron magnetic device, far infrared radiator, vibration massage device, pulse and electronic acupuncture and moxibustion device, nano bio-active multifunctional fibre and natural static traction therapeutic function into one body in which the above-mentioned all the therapeutic device are driven by a small motor with an eccentric hammer. It is safe and reliable in therapeutic effect.

The present invention relates to combination therapies for melanoma, and in particular, metastatic melanoma. Drugs for use in such therapies in include BRAF inhibitors such as PLX 4720 and PLX 4734 in combination with RO 31-8220, bafetinib or cardiac glycosides.

The invention relates to a traditional Chinese herbal preparation for preventing and treating foot and mouth diseases of cows. The traditional Chinese herbal preparation mainly comprises seven medicines such as coptidis rhizome, isatis root, radix scutellariae, sophora flavescens, honeysuckle and phillyrin. The traditional Chinese herbal preparation is prepared according to a Chinese veterinarian theory scientific formula, can resist viruses and improve partial ulcerated lesions and has the effects of clearing heat, cooling the blood, diminishing inflammation and eliminating the general symptoms as well as relieving asthma, inducing diuresis and the like. Therefore, the curative effect is definite and outstanding; the comprehensive curing effects of interior and exterior combination and treatment of both symptoms and root causes can be achieved; the curing rate is over 95 percent.

The invention relates to an external-use ointment for treatment of dermatopathy. The ointment is prepared by mixing and blending the following medicines (by weight): 6-9 parts of sulfamethoxazole, 5-8 parts of chloramphenicol, 5-8 parts of prednisone, 3-5 parts of borneol, 0-8 parts of sulfur flour, 5-8 parts of vitamin E, 4-8 parts of vitamin complex B, 6-10 parts of VC, 5-7 parts of B1, 0.01-0.04 part of triamcinolone acetonide, 10 parts of urea ointment, 30 parts of a Chinese herbal antibacterial paste, 8-10 parts of chlorpheniramine, 4-8 parts of chloramphenicol raw powder, 6-10 parts of metronidazole, 10 parts of B6 ointment, 0-15 parts of terbinafine hydrochloride emulsifiable paste and 0-10 parts of ketoconazole emulsifiable paste. The ointment of the invention is used for treatment of skin diseases such as dermatitis, eczema, acne, yellow fluid ulcers, manus and tinea pedis, psoriasis, etc., can be used for realizing antibiosis, anti-inflammation, itching-relieving and antiallergic functions and the function of boosting body immunity, reduces exudation and inflammatory response and promotes inflammatory resorption of wounds and growth of granulation tissues, and has a good comprehensive treatment effect.

The invention relates to an oral medicine for treating lung cancer, in particular to a Chinese medicine oral decoction for treating lung cancer, which is prepared by using Chinese herbal medicines as raw materials. The Chinese medicine oral decoction is characterized by using the following raw medicinal materials in parts by weight (unit: gram) as effective components: 20-35g of barbed skullcap herb, 25-35g of hairyvein agrimony, 15-25g of white gourd kernels, 25-35g of polygonum cuspidatum, 50-65g of oldenlandia diffusa and 25-35g of burdock. In the invention, all the raw medicinal materials are reasonably mixed to achieve the efficacies of clearing heat and detoxicating, resisting viruses, resisting tumors, dispelling wind and heat from the body, promoting blood circulation and inducing diuresis, removing blood stasis to stop pain, expelling phlegm and arresting coughing, and the like. Moreover, through organic combination with operation, radiotherapy, chemotherapy and the like in western medicine, the Chinese medicine oral decoction can treat lung cancer comprehensively by complementing the advantages and disadvantages of each raw medicinal material, and can play the role of reducing toxicity and enhancing efficacy. The Chinese medicine oral decoction achieves a better effect on prolonging the life time of patients and improving the living life of the patients with cancer.