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Aqueous extract of licorice, composition containing same, preparation method and use thereof

A technology of licorice water and extract, which can be applied in the directions of drug combination, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as exceeding the standard

Active Publication Date: 2022-04-05
中国科学院遗传与发育生物学研究所农业资源研究中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, since heavy metals such as copper, zinc and arsenic (with cadmium) are routine large-dose additives in the farming industry, heavy metals such as copper, zinc and cadmium in pork and chicken seriously exceed the standard

Method used

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  • Aqueous extract of licorice, composition containing same, preparation method and use thereof
  • Aqueous extract of licorice, composition containing same, preparation method and use thereof
  • Aqueous extract of licorice, composition containing same, preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1 Preparation of licorice water extract

[0067] 1000 g of commercially available licorice was washed with 5500 g of water and then pulverized by a pulverizer (FW135 Chinese herbal medicine pulverizer, Shanghai Keheng Industry) to obtain pulverized licorice. Then, take 500 g of the crushed licorice and soak it in water at 50°C for 40min, then extract twice with water at 60°C, and extract with water at a weight ratio of licorice:water=1:5 each time. The extraction time was 2h, and the extract was obtained. The extracts were combined to obtain a combined solution, which was filtered through vacuum filtration to obtain a filtrate, which was concentrated to a specific gravity of 0.8, and dried by dusting at 80° C. to obtain 52 g of licorice water extract 1.

Embodiment 2

[0068] Example 2 Preparation of licorice water extract

[0069] 1000 g of commercially available licorice was washed with 5000 g of water and then pulverized by a pulverizer (FW135 Chinese herbal medicine pulverizer, Shanghai Keheng Industry) to obtain pulverized licorice. Then, extract 500 g of the pulverized licorice with water for 3 times, extract the pulverized licorice with 5000 g of water according to the weight ratio of licorice:water=1:10 during the first extraction, and extract the pulverized licorice for the second time. During the third extraction, the extraction was performed with water according to the weight ratios of licorice:water=1:5 and 1:3, the temperature of the water used for the three extractions was 90°C, and the extraction time was 1.5h each time, thus obtaining the extraction liquid. The extracts were combined to obtain a combined solution and filtered through vacuum filtration to obtain a filtrate, which was concentrated to a specific gravity of 1.2,...

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PUM

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Abstract

The present invention relates to a licorice water extract, a composition containing the extract, a preparation method and an application of the extract, wherein the licorice water extract can efficiently discharge heavy metals, such as cadmium, from a subject.

Description

technical field [0001] The present invention relates to the field of natural products, in particular, the present application proposes to use a cheap, non-obvious animal-toxic edible natural extract of licorice to promote the efflux of heavy metals (such as cadmium) in animals, and specifically relates to licorice water extract , a composition comprising the extract, and a preparation method and use of the extract. Background technique [0002] The development of industry and agriculture in recent decades has made China in an era of comprehensive heavy metal pollution. Official documents show that the heavy metal pollution in the water bodies of major rivers, lakes and reservoirs in China exceeds 80%, and the soil pollution exceeds the standard rate of 19.4%. Among all pollutants, cadmium has the highest rate of exceeding the standard and is the most serious and widespread heavy metal. Market research shows that the excess rate of heavy metals, especially cadmium, in rice ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A61P39/02
CPCA61K36/484A61K2236/51A61K2236/39A61K2236/331
Inventor 李小方郑鑫
Owner 中国科学院遗传与发育生物学研究所农业资源研究中心