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Preparation method of porous titanium-based drug atomization core and heating component for atomization

A technology of heating components and atomizing cores, which is applied in the direction of medical devices, nebulizers for treatment, and other medical devices. The effect of cost and large contact area

Active Publication Date: 2020-07-17
UNIV OF SCI & TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the medical nebulizers on the market are ultrasonic and air-compressed, which are not only expensive, but also large in size and inconvenient to carry. It is difficult to meet people's requirements for drug delivery nebulizers.

Method used

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  • Preparation method of porous titanium-based drug atomization core and heating component for atomization
  • Preparation method of porous titanium-based drug atomization core and heating component for atomization

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A porous titanium-based drug atomization core and a heating element for atomization are prepared. Prepare as follows:

[0038] (1) The purity is 90%, and the particle size is 50 μ m industrial titanium powder, adhesive is mixed and stirred evenly according to a certain ratio as the porous matrix raw material for subsequent use, denoted as a, wherein titanium powder accounts for 55wt%, and adhesive accounts for 45wt% , the binder is composed of paraffin wax: polypropylene: stearic acid = 65:30:5 (m:m:m) system; then mix nickel-chromium alloy powder, methyl cellulose (MC) and deionized water evenly, Denoted as b, wherein the mass ratio of nickel-chromium alloy powder to methyl cellulose (MC) is 10:1, and deionized water is added to make the solid content of b raw material 60wt%. Put the raw materials of a and b into the planetary ball mill for mixing, wherein the ball-to-material ratio is 4:1, the diameter of the corundum ball is 1-5mm, the ball milling speed is 150r / min...

Embodiment 2

[0044] A porous titanium-based drug atomization core and a heating element for atomization are prepared. Prepare as follows:

[0045] (1) The industrial titanium alloy powder with a purity of 95% and a particle size of 80 μm, an adhesive and deionized water are mixed and stirred evenly according to a certain proportion and used as a raw material of a porous matrix for later use, which is recorded as a. Among them, the titanium-titanium alloy powder accounts for 85wt%, and the binder accounts for 15wt%. The binder is composed of methylcellulose:polyethylene glycol=1:1 system, and the solid content is 80wt.%. Then mix nickel-chromium alloy powder, methyl cellulose (MC) and deionized water evenly, denoted as b, wherein the mass ratio of nickel-chromium alloy powder to methyl cellulose (MC) is 18:1, and then add deionized The water was such that the solids content of the b material was 75% by weight. Put the raw materials of a and b into the planetary ball mill for mixing, where...

Embodiment 3

[0051] A porous titanium-based drug atomization core and a heating element for atomization are prepared. Prepare as follows:

[0052] (1) Stir the industrial titanium alloy TC4 powder with a purity of 92% and a particle size of 120 μm, a binder and deionized water according to a certain ratio and use it as a solid phase raw material for later use, denoted as a, wherein the binder is methyl The mass ratio of cellulose, titanium powder and binder is 90:10, and the solid content of raw material a is 90%; then the nickel-chromium-iron alloy powder, methyl cellulose and deionized water are mixed evenly, and it is recorded as b, wherein nickel The mass ratio of ferrochrome alloy powder to methyl cellulose is 9:1, and deionized water is added to make the solid content of b to be 80%. Put the a and b slurries into the planetary ball mill respectively for mixing, wherein the ball-to-material ratio is 4:1, the diameter of the corundum ball is 1-5mm, the ball milling speed is 100r / min, ...

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Abstract

The invention discloses a porous titanium-based drug delivery and atomization core and a preparation method of a heating assembly for atomization, and belongs to the field of porous composite metal materials. Porous titanium and a titanium alloy are used as a base material of the drug delivery and atomization core, nickel chromium and other alloy materials are used as a heating resistor layer, andthe novel porous titanium-based drug delivery and atomization core and the heating assembly for atomization are prepared through various molding technologies. According to the preparation method, bio-friendly material titanium is used as a matrix raw material, and alloy materials such as nickel chromium are used as the heating resistor layer, so that the heating assembly has the advantages of safety, no toxicity, pore controllability, oxidation resistance, corrosion resistance, good chemical stability, easiness in sintering and the like; and the heating resistor layer is tightly combined witha matrix, so that the problem that a combination of a ceramic porous matrix and the heating resistor layer is easy to fall off is solved. The drug delivery and atomization core prepared by the preparation method and an atomizer assembled by the heating assembly for atomization show good atomization performance, and the atomization airflow is uniform and stable, thus the preparation technology ofthe drug delivery and atomization core is improved and simplified and the machining cost is reduced.

Description

technical field [0001] The invention belongs to the field of preparing porous composite metal materials, and provides a method for preparing a porous titanium-based drug delivery atomizing core and a heating resistance layer for atomization by various molding methods including injection molding, dry pressing molding, and 3D cold printing. Background technique [0002] As a material with many advantages such as high strength, good corrosion resistance, and high heat resistance, titanium alloy is often used as an artificial bone implant material in medicine due to its excellent bio-friendliness and pore-forming properties. , filter material, etc. The porous titanium-based drug atomization core and heating components prepared by pulping, molding and sintering processes from titanium alloys, nickel-chromium, nickel-chromium-iron and other alloys have good porosity and bonding strength. It can realize rapid and accurate preparation of the atomizing core and its heating component...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B22F3/11B22F3/22B22F5/00A61M11/04
CPCA61M11/042A61M2207/00B22F3/11B22F3/225B22F5/00B22F2003/242B22F2998/10B22F2999/00B22F2009/043B22F3/1021B22F3/1007B22F2201/02B22F2201/20
Inventor 杨芳林圣增秦乾郭志猛周洋陈存广路新邵艳茹孙海霞张策芦博昕严梦婕冯钊红
Owner UNIV OF SCI & TECH BEIJING
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