Composition for pediatric cancer patients to eat

A tumor patient and composition technology, applied in the directions of bacteria, food science, and application used in food preparation, can solve the problems of not being able to inhibit tumor growth and not suitable for tumor patients, and achieve repairing intestinal mucosal damage and inhibiting tumors. Cell growth, the effect of reducing the production of ROS

Pending Publication Date: 2019-04-19
吕麟亚 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] At present, most of the existing commercially available ketogenic diets are aimed at patients with refractory epilepsy. The composition of medium-chain fatty acids provided in it is not suitable for tumor patients, and no probiotics and glutamine are added, which cannot inhibit tumor growth and protect chemotherapy. The purpose of improving the patient's intestinal mucosa, restoring the dominant intestinal microecology and enhancing chemotherapy sensitivity

Method used

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  • Composition for pediatric cancer patients to eat
  • Composition for pediatric cancer patients to eat
  • Composition for pediatric cancer patients to eat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A composition aimed at children with tumors less than 1 year old, the nutrient content per 100mL nutrient solution is shown in the following table:

[0031]

[0032]

[0033] The edible composition of this embodiment is measured by "Determination FM-8P Type Automatic Freezing Point Remanent Osmometer", the osmotic pressure range is 150mOsm / L~160mOsm / L, within the range that children can tolerate (400mOsm / L within L).

Embodiment 2

[0035] A composition aimed at children with tumors aged 1 to 2 years old, the nutrient content per 100mL nutrient solution is shown in the following table:

[0036]

[0037]

[0038] The edible composition of this embodiment is measured by "Singce FM-8P type automatic freezing point residual osmometer", and the osmotic pressure range is 180mOsm / L~190mOsm / L, which is within the range that children can tolerate (400mOsm / L within L).

Embodiment 3

[0040] A composition aimed at children with tumors aged 3 to 5 years old, the nutrient content per 100mL nutrient solution is shown in the following table:

[0041]

[0042]

[0043] The edible composition of this embodiment is measured by "Determinate FM-8P type automatic freezing point residual osmometer", and the osmotic pressure range is 210mOsm / L~230mOsm / L, which is within the range that children can tolerate (400mOsm / L within L).

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Abstract

The invention belongs to the field of food, and particularly relates to a composition for pediatric cancer patients to eat. The composition comprises protein, fat, carbohydrate, multi-vitamins, mineral elements and glutamine. In the composition, the fat serves as a main ingredient and provides calories, energy generated by cancer cells through a glucose anaerobic glycolysis path and essential groups of cancer cell DNA replication are blocked, and the aims of starving cancer cells and inhibiting cancer cell growth are achieved. According to the composition for pediatric cancer patients to eat,medium chain triglyceride contained in the composition can intensify the in-vivo ketogenic effect of patients, and child cancer cells are specificity starved. Intestinal-mucosa damage caused by chemotherapy drugs can be prevented and repaired through the added glutamine, an intestinal micro-ecosystem can be adjusted through added bifidobacterium triple viable bacteria, and an antitumor immunity mechanism of the body is activated; meanwhile, the composition has the high-energy density and the suitable osmotic pressure, malnutrition can be effectively improved, and the composition also has the intestinal-receptivity advantage, and is particularly suitable for child patients.

Description

technical field [0001] The invention relates to the field of dietary formulations for patients, in particular to a composition for children with tumors. Background technique [0002] In recent years, the incidence of malignant tumors in children is increasing, and the disease progresses rapidly. For example, the 5-year disease-free survival rate for patients with advanced neuroblastoma is less than 40%. Although radiotherapy, chemotherapy, surgery and other comprehensive treatments are used clinically, they are limited by many limitations due to limited curative effect, large side effects and many complications. The nutritional status and quality of life of children are often unsatisfactory, which has always been a difficult problem in clinical treatment. Therefore, for a long time, exploring new methods of adjuvant tumor therapy has been the direction of researchers' efforts. [0003] In recent years, with the proposal of the theory that "cancer is a metabolic disease", t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A23L33/135A23L33/175
CPCA23L33/135A23L33/175A23L33/40A23V2002/00A23V2400/113A23V2400/51A23V2250/062A23V2200/308
Inventor 孔粼吕麟亚孔祥如章均彭亮杨超邓晓斌赵珍珍杜一飞周建武彭俊伟贺娇
Owner 吕麟亚
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