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A poct microfluidic chip with integrated self-aligning lens and its preparation method

A microfluidic chip, self-alignment technology, applied in the direction of lenses, chemical instruments and methods, laboratory containers, etc., can solve the problems of low integration, complex alignment and adjustment of optical devices, etc., and achieve high motion accuracy , The effect of high laser processing efficiency and convenient design process

Active Publication Date: 2021-09-24
DALIAN UNIV OF TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] In view of the above situation, in order to overcome the existing technical defects, the present invention provides a POCT microfluidic chip integrated with a self-aligning lens, which solves the problems of complex alignment and low integration of optical devices in POCT optical detection equipment

Method used

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  • A poct microfluidic chip with integrated self-aligning lens and its preparation method
  • A poct microfluidic chip with integrated self-aligning lens and its preparation method
  • A poct microfluidic chip with integrated self-aligning lens and its preparation method

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Embodiment Construction

[0026] Embodiments of the present invention will be described in detail below, and the embodiments are illustrated in the drawings in which the same or similar components have the same or similar elements, which are identical or similar, in the drawings. The following is exemplary by way of reference to the accompanying drawings, and is intended to be construed as limiting the invention.

[0027] like figure 1 As shown, a POCT microfluidic chip integrating self-alignment lens is polymethyl methacrylate (PMMA), consisting of three layers, ie cover sheet 1, microchannels, and lens layer 4 and the film layer 11; There is an inlet port 2 and an exhaust hole 3 on the cover sheet 1; a microchannel and an integrated self-alignment lens 8 on the microchannels and lens layers 4, and the microchannels are provided with injective chamber 5, delay control cavity. Chamber 6, the detection chamber 7 and the waste liquid collection chamber 9; the integrated self-alignment lens 8 is in the form o...

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Abstract

The invention belongs to the technical field of real-time detection of polymer microfluidic chips, and in particular relates to a POCT microfluidic chip integrated with a self-aligning lens and a preparation method thereof. The microfluidic chip includes a cover layer, a microchannel, a lens layer and a bottom layer; the microchannel and the lens layer are provided with microchannels, and integrated self-aligning lenses on both sides of the microchannel; the integrated self-aligning lens is a specific The lens arc surface structure, the curvature radius and focal length of the lens are determined according to the theory of geometric optics, ensuring that the lens focus is in the microchannel detection area; the thickness of the microfluidic chip microchannel and lens layer is 50-5000 μm; the microchannel and lens arc structure The shape, size and relative position of the laser are designed in the laser drawing software, and the laser processing is used for one-time processing. It has self-alignment characteristics and avoids complicated optical alignment processes. The invention integrates the lens on the microfluidic chip, reduces the volume and cost of the detection equipment, and is of great significance for realizing real real-time detection.

Description

Technical field [0001] The present invention belongs to the field of instant detection of polymer microfluidic chips, and in particular to a POCT microfluidic chip integrating self-alignment lens and a preparation method thereof. Background technique [0002] POCT (POINT-OF-CARE TESTING) is also named instant testing or on-site testing. In recent years, the National Clinical Biochemistry Academy has been defined as "the treatment of the patient, which is close to the patient treatment in recent years" POCT evidence-based document ". Clinical personnel or patients undergoing clinical implementation of interior discipline training. POCT is based on traditional laboratory medicine, all rapid test and clinical applications other than traditional, core or central laboratories. Laboratory Medicine Although the detection accuracy is high, it is necessary to use large biochemical testing equipment as diagnostic tools, and these large biochemical detection equipment are expensive and comp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L3/00G02B3/00
CPCB01L3/502707B01L2200/027B01L2200/0689B01L2200/10B01L2300/0654B01L2300/12G02B13/0015
Inventor 李经民梁超刘冲牛爱英
Owner DALIAN UNIV OF TECH
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