POCT microfluidic chip with integrated self-aligning lenses and preparation method of POCT microfluidic chip

Abstract

The invention belongs to the technical field of instant detection of polymer microfluidic chips, and particularly relates to a POCT microfluidic chip with integrated self-aligning lenses and a preparation method of the POCT microfluidic chip. The microfluidic chip comprises a cover sheet layer, a microchannel and lens layer and a bottom sheet layer; the microchannel and lens layer is provided witha microchannel and the integrated self-aligning lenses on both sides of the microchannel; the integrated self-aligning lenses are of a specific lens arc-surface structure, the radius of curvature andthe focal length of the lenses are determined according to the geometric optical theory, and it is ensured that the focuses of the lens are located in a detection area of the microchannel; the thickness of the microchannel and lens layer of the microfluidic chip is 50-5,000 microns; the shapes, sizes and relative positions of the microchannel and the lens arc structures are designed in laser drawing software, processing and forming are conducted at a time through laser machining, the self-aligning property is achieved, and the complicated optical aligning process is avoided. The lenses are integrated on the microfluidic chip, the size and cost of detection equipment are reduced, and important significance is provided for the achievement of real instant detection.

Description

technical field [0001] The invention belongs to the technical field of real-time detection of polymer microfluidic chips, and in particular relates to a POCT microfluidic chip integrated with a self-aligning lens and a preparation method thereof. Background technique [0002] POCT (Point-of-care testing) is also known as point-of-care testing or on-site testing. Clinical tests performed by clinical personnel or patients themselves who have received training in the clinical implementation room. POCT is based on traditional laboratory medicine, all rapid tests and clinical applications performed outside traditional, core or central laboratories." Although laboratory medicine has high detection accuracy, it needs large-scale biochemical detection equipment as a diagnostic tool. Most of these large-scale biochemical detection equipment are expensive and complicated to operate. In contrast, the current diagnosis is more and more towards the trend of portable and rapid instant de...

AI Technical Summary

Problems solved by technology

[0006] In view of the above situation, in order to overcome the existing technical defects, the present invention provides a POCT microfluidic chip integrated with a self-aligning lens, which solves the problems of complex alignment and low integration of optical devices in POCT optical detection equipment

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