Gynecology department pelvic floor cold application plaster used for postnatal vulva detumescence and analgesia

A gynecological and vulvar technology, applied in the directions of extracellular fluid diseases, non-central analgesics, medical preparations with non-active ingredients, etc. , to avoid perineal pain, reduce liver and kidney toxicity, and avoid first-pass effect

Inactive Publication Date: 2019-04-26
南京曼宝韵生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, there are certain problems in the use of perineal cold compress pads. For example, if the temperature is too low, women's genitals may be frostbitten and suffer secondary damage; the surface of the cold compress pads is too dry or made of water-absorbent fabrics, which may cause

Method used

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  • Gynecology department pelvic floor cold application plaster used for postnatal vulva detumescence and analgesia
  • Gynecology department pelvic floor cold application plaster used for postnatal vulva detumescence and analgesia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The gel layer used in this experiment contains the following mass percentage compositions: The gel layer contains the following mass percentage compositions: 0.1% hyaluronic acid, 0.25% glycerin, 0.2% ethylparaben, 0.2% % carbomer, 0.25% poloxamer, 0.75% pH regulator, 5.5% hazelnut extract, 3.5% angelica extract, 0.1% medical zinc oxide, 0.9% peppermint Brain and cooling agent, the rest is purified water.

[0026] In this example, hyaluronic acid can provide a better water environment while promoting collagen growth; herbal extracts can provide a better microenvironment and supplement nutrients.

Embodiment 2

[0028] On the basis of the ratio of the above ingredients, the inventor also believes that other auxiliary ingredients can be added to the hyaluronic acid dressing, so in this embodiment, a space for adding other auxiliary ingredients is reserved in the above ingredients, specifically In terms of mass percentage: 0.4% hyaluronic acid, 0.2% glycerin, 0.1% ethylparaben, 0.2% carbomer, 0.25% poloxamer, 0.75% pH regulator, Shanze Orchid extract 5%, Angelica extract 5%, 77.2% water, 10.0% other auxiliary ingredients.

[0029] In this example, the gel layer prepared by using the above-mentioned proportions in the experiment basically continued the effect of Example 1, and the therapeutic effect could be superimposed according to the added auxiliary ingredients other than the above-mentioned ingredients; but it needs to be explained Yes, the above-mentioned 10.0% other auxiliary ingredients should be substances with mild chemical properties, which cannot conflict with the chemical pr...

Embodiment 3

[0031] A total of 400 cases of vaginal delivery women who were admitted to the obstetrics department of the cooperative hospital from June 2014 to June 2018 were selected, and none of them received epidural analgesia. According to the random number table method, they were divided into treatment group and control group, with 200 cases in each group. All patients in the two groups were primiparous, and the newborns and maternal patients were healthy, without pregnancy complications, and without breastfeeding contraindications. There was no significant difference between the two groups in clinical data such as age and gestational week (all P>0.05), which were comparable.

[0032] The treatment group applied the cold compress obtained in Example 1 of the present invention, and the puerpera used it for the first time after the delivery debridement was clean, 15 minutes / time, 2 times / d, and the treatment ended when she was discharged from the hospital within 48 hours.

[0033] Patie...

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PUM

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Abstract

The invention discloses a gynecology department pelvic floor cold application plaster used for postnatal vulva detumescence and analgesia, and can effectively alleviate pain, edema and hematoma causedby delivery, prevent infection and accelerate perineum recovery. The cold application plaster comprises a nonwoven backlining layer, a polyethylene film coverage layer and a gel layer, wherein the gel layer is prepared from the following ingredients in percentage by mass: 0.05-0.5% of hyaluronic acid, 0.05-0.5% of glycerinum, 0.025-0.5% of ethylparaben, 0.1-0.5% of pH (Potential of Hydrogen) regulator, 3.5-6.5% of herba elatostema macintyrei dunn extractive, 3.5-6.5% of radix angelicae sinensis extractive, 0.01-0.5% of medical zinc oxide, 0.5-3% of menthol, cool storage agent and the balanceof pure water. According to the gynecology department pelvic floor cold application plaster, the temperature of vulva can be lowered, the sensitiveness of nerve endings can be lowered, pain is lightened, capillaries are contracted to inhibit vascular permeability, effusion is reduced, local edema and hematoma is alleviated, inflammatory mediator releasing is inhibited, bacteria activity is lowered, in addition, the wettability of the vulva can be kept, dry and cold stimulation is avoided, collagen hyperplasia is accelerated, and damaged vulva healing is accelerated.

Description

technical field [0001] The invention relates to a gynecological pelvic floor cold compress which can be used for postpartum vulva detumescence and pain relief. Background technique [0002] When the parturient gives birth, the local perineum is excessively compressed, resulting in capillary rupture and increased permeability of the blood vessel wall, allowing the fluid in the tube to penetrate into the surrounding tissue space; the side incision operation will destroy the normal tissue structure of the perineum, resulting in local tissue congestion; because the perineum is located in the sacrum Nerve innervation area, the nerve distribution in this area is wide, the sensitivity is high, and the tissue gap in this area is large at the same time. Under the action, it is easy to cause tissue reactive edema; the fetal head oppresses the perineum for a long time, affects the perineal venous return, causes perineal tissue ischemia and hypoxia, and easily causes local tissue edema,...

Claims

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Application Information

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IPC IPC(8): A61K36/232A61K9/70A61K47/14A61K47/10A61K47/36A61K47/32A61P15/00A61P7/10A61P29/00
CPCA61K36/232A61K9/0034A61K9/7023A61K36/185A61K47/10A61K47/14A61K47/32A61K47/36A61P7/10A61P15/00A61P29/00A61K2300/00
Inventor 孙林
Owner 南京曼宝韵生物科技有限公司
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