Feed additive for preventing and treating body surface ulcer disease of sea bass

Abstract

The present invention provides a feed additive for preventing and treating the body surface ulcer disease of sea bass and belongs to the technical field of aquaculture. The feed additive comprises anextracellular polysaccharide mixture and avocado coarse powder containing mannoheptulose, wherein a preparation method of the extracellular polysaccharide mixture is as follows: marine microorganismsare fermented in a medium containing 5-aza-2-deoxycytidine and ammonium citrate, after the fermentation, sterilization is conducted, filtering is conducted to separate fermentation liquid and mycelia,and the fermentation liquid is concentrated to be dry to obtain the extracellular polysaccharide mixture; and a preparation method of the avocado coarse powder containing the mannoheptulose is as follows: avocado tree leaves are crushed, water containing 2-chloroethylamine hydrochloride is added, cellulase is added for digestion, and filtering and concentrating are conducted. The feed additive can response to micro-organism attack, can increase the rate of wound healing, avoids certain bacterial infections, achieves purposes of preventing and treating the body surface ulcer disease of the seabass, prevents feed from being deteriorated, endows the feed with natural meat flavor, improves the feeding rate of the sea bass, and finally improve the survival rate of the sea bass.

Description

technical field [0001] The invention belongs to the technical field of aquaculture, and in particular relates to a feed additive for preventing and treating sea bass body surface ulcer disease. Background technique [0002] Fish and other aquaculture animals live in the water environment, and environmental changes have a great impact on it, which often causes stress responses in fish and induces the occurrence and development of various diseases. However, people cannot intuitively understand and diagnose the occurrence of diseases and the progress of diseases like terrestrial animals. Most of the diagnosis and prevention are based on the feeding and activity status of fish schools, or after the occurrence of diseased and dead fish, which is often delayed after the pathogen is identified The most suitable time for prevention and treatment. Canker disease is a common disease on the body surface of sea bass. Its onset season is wide and the mortality rate is high. The onset se...

AI Technical Summary

Problems solved by technology

The disadvantage is that the cure rate is low, and due to drug residues, eating the cured grouper will affect people's health. In addition, the abuse of antibiotics will increase the resistance of bacteria, which is not conducive to the healthy and sustainable development of aquaculture.

At present, some people have also developed a vaccine for grouper canker disease, which uses formalin inactivated vaccine, heat inactivated vaccine and crude lipopolysaccharide extracted from Vibrio vulnificus, which are virulent strains of Vibrio vulnificus. Inoculation of grouper and grouper, however, the operation is cumbersome, the cost is high, and it is used for disease control in aquaculture production, and the effect is very poor