Application of infantile common cold preparation in preparation of drug for resisting herpes simplex virus

A technology of herpes simplex virus and Xiaoer Ganmaoning, which is applied in the field of medicine, can solve problems such as blindness, aggravated corneal turbidity, and difficulty in treatment, and achieve the effect of low toxicity, strong effect, and important social value

Inactive Publication Date: 2019-05-03
JIANGXI POZIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective drug to control recurrence, and its treatment is difficult, which has become the most difficult problem in ophthalmology
Corneal opacity gradually worsens after repeated attacks, eventually leading to blindness
However, there is no report on Xiaoer Ganmaoning preparation against herpes simplex virus

Method used

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  • Application of infantile common cold preparation in preparation of drug for resisting herpes simplex virus
  • Application of infantile common cold preparation in preparation of drug for resisting herpes simplex virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 Preparation of Xiao'er Ganmaoning Mixture

[0019] Test drug: Xiaoer Gan Gan Ning Mixture. The specific preparation method of described test drug is made up of the following steps:

[0020] Mint 70g, nepeta ear 60g to extract volatile oil; bitter almond 70g to produce almond water; burdock fruit 70g, baicalin 70g, bellflower 60g, peucedanum 70g, angelica dahurica 20g, fried gardenia 30g, burnt hawthorn 20g, burnt Liushenqu 20g, coke 20g of malt, 100g of reed root, 100g of honeysuckle, 70g of forsythia, add 6 times of water to decoct twice, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrates, let stand for 48 hours, take the supernatant and concentrate To an appropriate amount, add 200g of sucrose, stevia and an appropriate amount of preservatives, boil to dissolve, add almond water to mix, let it stand, take the supernatant, add volatile oil, essence, etc., stir as you add, add water to 1000ml, stir well, Filter, pack and...

Embodiment 2

[0021] Embodiment 2 Preparation of Xiao'er Ganmaoning Mixture

[0022] Test drug: Xiaoer Gan Gan Ning Mixture. The specific preparation method of described test drug is made up of the following steps:

[0023] Mint 80g, nepeta ear 67g to extract volatile oil; bitter almond 80g to produce almond water; burdock fruit 80g, baicalin 80g, bellflower 67g, peucedanum 80g, angelica dahurica 27g, fried gardenia 40g, burnt hawthorn 27g, burnt Liushenqu 27g, coke 27g of malt, 120g of reed root, 120g of honeysuckle, 80g of forsythia, add 6 times of water and decoct twice, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrate, let it stand for 48 hours, take the supernatant and concentrate To an appropriate amount, add 200g of sucrose, stevia and an appropriate amount of preservatives, boil to dissolve, add almond water to mix, let it stand, take the supernatant, add volatile oil, essence, etc., stir as you add, add water to 1000ml, stir well, Filter, pack ...

Embodiment 3

[0024] Embodiment 3 Preparation of Xiao'er Ganmaoning Mixture

[0025] Test drug: Xiaoer Gan Gan Ning Mixture. The specific preparation method of described test drug is made up of the following steps:

[0026] Mint 90g, Nepeta ear 75g to extract volatile oil; Bitter almond 90g to produce almond water; Arctium 90g, Scutellaria baicalensis 90g, Campanulaceae 75g, Peucedanum 90g, Angelica dahurica 35g, Fried gardenia 50g, Jiao Hawthorn 35g, Jiaoliu Shenqu 35g, 35g of malt, 140g of reed root, 140g of honeysuckle, 90g of forsythia, add 6 times of water and decoct twice, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrate, let it stand for 48 hours, take the supernatant and concentrate To an appropriate amount, add 200g of sucrose, stevia and an appropriate amount of preservatives, boil to dissolve, add almond water to mix, let it stand, take the supernatant, add volatile oil, essence, etc., stir as you add, add water to 1000ml, stir well, Filter, ...

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Abstract

The invention relates to the field of medicines, in particular to an application of a traditional Chinese medicine preparation in preparation of a drug for resisting herpes simplex virus. The infantile common cold preparation comprises raw materials in parts by weight as follows: 70-90 parts of mint, 60-75 parts of herba schizonepetae, 70-90 parts of bitter apricot seeds, 70-90 parts of fructus arctii, 70-90 parts of scutellaria baicalensis, 60-75 parts of platycodon roots, 70-90 parts of radix peucedani, 20-35 parts of radix angelicae, 30-50 parts of stir-fried fructus gradeniae, 20-35 partsof parched hawthorn fruits, 20-35 parts of parched medicated leaven, 20-35 parts of parched malt, 1001-40 parts of rhizoma phragmitis, 100-140 parts of honeysuckle flowers and 70-90 parts of fructus forsythiae. The infantile common cold preparation has remarkable inhibition effects on the herpes simplex virus, has the advantages of small toxicity, strong effect, safety, effectiveness and the like,opens up a new way for prevention and tretament of diseases caused by the herpes simplex virus and has important social values and economic values.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the use of a traditional Chinese medicine preparation in the preparation of anti-herpes simplex virus medicine. Background technique [0002] Herpes simplex is a viral skin disease caused by herpes simplex virus, which is called heat sore in traditional Chinese medicine. [0003] Herpes simplex virus belongs to the subfamily Alphaviridae of the Epiviridae family. It is a DNA virus with two serotypes, type I and type II. Humans are its only host. Type I herpes simplex virus (HSV-1) mainly infects the skin and mucous membranes of the face, causing herpetic keratitis, herpetic encephalitis, gingivitis, pharyngitis or tonsillitis, and herpetic eczema. [0004] According to statistics, the HSV-1 serotype positive in the current population is relatively high, about 90%. Neurotropic, can establish a latent infection in the central nervous system, and relapse in immunocompromised conditions. H...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K36/8998A61P31/22
Inventor康兴东周朝忠张金良胡吉忠刘九平刘厚权李小锋陈梁董艳凯
OwnerJIANGXI POZIN PHARMA