Oral thick paste capable of increasing white blood cell content and preparation method thereof

A white blood cell and content technology, applied to medical preparations containing active ingredients, extracellular fluid diseases, pharmaceutical formulas, etc., can solve problems such as consumption, large ethanol, and many operating steps, and achieve wide source of raw materials, small impact, and overcome easy caking effect

Active Publication Date: 2019-05-03
HUNAN BUTIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Both of the above two processes require secondary alkalization and ethanol reaction system, and there are many operation steps and consume a large amount of ethanol

Method used

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  • Oral thick paste capable of increasing white blood cell content and preparation method thereof
  • Oral thick paste capable of increasing white blood cell content and preparation method thereof
  • Oral thick paste capable of increasing white blood cell content and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Described carboxymethyl pachyrhin is prepared by following method:

[0032] S1. Cultivation of Poria cocos: aseptically inoculate Poria cocos hyphae in wort juice liquid medium, and cultivate at 28°C for 4 days;

[0033] S2. Preparation of Poria cocos polysaccharide: Ferment the cultured Poria cocos medium at 35°C for 2 days, heat to a slight boil, extract for 1 hour, filter, add 3 times the amount of mixed solvent of chloroform and n-butanol, the chloroform and n-butanol The mixed volume ratio is 4:1, shaken, centrifuged, add 3 times the amount of 95% ethanol, overnight, filter to obtain a precipitate, wash 2 times with ether to obtain pachyman;

[0034] S3. Preparation of Poria Cocos Polysaccharide: Add 10g of Poria cocos polysaccharide into 100mL0.5mol / L sodium periodate solution for selective oxidation, adjust the pH value to 3 with trifluoroacetic acid, moderate acid hydrolysis, acid hydrolysis time is 30min, filter , washing the solid with water to obtain Poria c...

Embodiment 2

[0038] Described carboxymethyl pachyrhin is prepared by following method:

[0039] S1. Cultivation of Poria cocos: aseptically inoculate Poria cocos hyphae in wort liquid culture medium, and cultivate at 28° C. for 5 days;

[0040] S2. Preparation of Poria cocos polysaccharide: Ferment the cultured Poria cocos medium at 35°C for 2 days, heat to a slight boil, extract for 2 hours, filter, add 5 times the volume of a mixed solvent of chloroform and n-butanol, the chloroform and n-butanol The mixed volume ratio is 6:1, shaken, centrifuged, add 3 times the amount of 95% ethanol, overnight, filter to obtain a precipitate, wash 3 times with ether to obtain pachymane;

[0041] S3. Preparation of Poria Cocos Polysaccharide: Add 10g of Poria cocos polysaccharide into 30mL 1.5mol / L sodium periodate solution for selective oxidation, adjust the pH value to 4 with trifluoroacetic acid, moderate acid hydrolysis, acid hydrolysis time is 1h, filter , washing the solid with water to obtain Po...

Embodiment 3

[0045] Described carboxymethyl pachyrhin is prepared by following method:

[0046] S1. Cultivation of Poria cocos: aseptically inoculate Poria cocos hyphae in wort juice liquid medium, and cultivate at 28°C for 4 days;

[0047] S2. Preparation of Poria cocos polysaccharide: Ferment the cultured Poria cocos medium at 35°C for 2 days, heat to a slight boil, extract for 2 hours, filter, add a mixed solvent of chloroform and n-butanol, the mixing volume ratio of chloroform and n-butanol 5:1, shake, centrifuge, add 3 times the amount of 95% ethanol, overnight, filter to get precipitate, wash 3 times with diethyl ether to obtain pachyrhin;

[0048] S3. Preparation of Poria Cocos Polysaccharide: Add 10g of Poria cocos polysaccharide into 50mL 1.0mol / L sodium periodate solution for selective oxidation, adjust the pH value to 3.6 with trifluoroacetic acid, moderate acid hydrolysis, acid hydrolysis time is 45min, filter , washing the solid with water to obtain Poria cocos polysaccharid...

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Abstract

The present invention proposes an oral thick paste capable of increasing white blood cell content. The oral thick paste is prepared from the following raw materials in parts by weight: 10-20 parts ofCarboxymethylpachymaran, 12-17 parts of colostrum basic protein, 5-10 parts of wheat oligopeptide, 35-40 parts of mulberry, 5-10 parts of longan aril, 10-20 parts of coix seeds, 20-25 parts of solomonseal rhizomes, 10-20 parts of Chinese yams, 20-25 parts of jujubes and 15-20 parts of honey. The oral thick paste of the invention has the functions of enhancing the immunity of the body, increasing the content of white blood cells in the blood and improving the body's hypoxia tolerance, and has a definite therapeutic effect of treating diseases such as low immune function and leukopenia. The rawmaterial source of the invention is wide, the preparation method is simple, and the prepared oral thick paste has a good immune enhancement effect, can promote white blood cell content, stimulate lymphocyte proliferation and reduce the morbidity of the body, and has broad application prospects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine health care, in particular to an ointment with the ability to increase the content of white blood cells. Background technique [0002] In recent years, the worldwide decline in environmental quality and the increase in people's life pressure have led to an increasing number of people in a sub-healthy state. At the same time, with the continuous improvement of living standards, people are paying more and more attention to personal health issues. With the enhancement of people's health awareness, people gradually began to choose healthy food and beverages. This demand caused the market share of carbonated beverages to decline continuously. Tea beverages, coarse grain beverages, fruit juice beverages and functional beverages began to be favored by people. To enhance immunity, it is necessary to ensure the content of amino acids in physical strength. The existence of amino acids i...

Claims

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Application Information

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IPC IPC(8): A61K38/01C08B37/00A61P7/00A61P37/04A61P39/00A61K31/715A61K35/644
Inventor 戴鑫汶戴甲木孙梦锦龙孝金邹奇张豪唐心文
Owner HUNAN BUTIAN PHARMA
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