Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

A technology for hair growth and skin trauma, applied in drug combination, skin diseases, drug delivery, etc., can solve the problems of wound healing speed, lack of formula, etc., achieve shortened film forming time, good integrity, and promote hair growth Effect

Active Publication Date: 2021-10-15

GUANGXI NORMAL UNIV

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AI-Extracted Technical Summary

Problems solved by technology

Although the preparation makes the treatment of the wound more convenient and prevents infection than the existing wound healing med...

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Method used

In summary, the present invention has a good ability to promote wound healing, wherein Chinese medicine polyphylla and other medicines are used to cooperate, have a synergistic effect, and jointly play the effect of anti-inflammatory, antibacterial and repair skin tissue, macromolecule The film-forming material is used as a carrier to better fit the skin surface. Tests have proved that this product has r...

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Abstract

The invention provides a combined medicine for promoting skin wound healing and hair growth and a preparation method thereof, belonging to the technical field of wound treatment. The drug is mainly prepared from the following raw materials in parts by weight: 12-16 parts of hydroxypropyl methylcellulose, 22-28 parts of polyvinylpyrrolidone, 26-32 parts of glycerol, 22-27 parts of iodophor solution, shell Polysaccharide hydrochloride 3-6 parts and Chonglou 3-5 parts. The preparation method is to weigh polyvinylpyrrolidone, add 13-16% aqueous solution of hydroxypropyl methylcellulose, 8-12% aqueous solution of chitosan hydrochloric acid, and the extract of S. chinensis, then add glycerol and iodophor, and stir After dissolving and degassing, the combined medicine is obtained. The drug forms a dense protective film on the wound to protect the secondary injury of the wound and sterilizes and reduces inflammation through traditional Chinese medicine. At the same time, it promotes wound healing through polymer materials, can shorten the time of wound healing, and has the function of promoting hair growth. .

Application Domain

Antibacterial agentsOrganic active ingredients +11

Technology Topic

Hydroxypropylmethyl celluloseIodide +18

Image

Examples

Experimental program(3)
Comparison scheme(2)
Effect test(1)

Example Embodiment

[0044] Example 1

[0045] Starting material: hydroxypropyl methyl cellulose 12g, polyvinylpyrrolidone 22g, glycerin 26g, iodine solution 22g, chitosan hydrochloride and re-building 3g 3g.

[0046] It was prepared by the following method:

[0047] (1) ready hydroxypropylmethylcellulose 12g, glycerin 26g, iodine solution 22g, chitosan hydrochloride and re-building 3g 3g, 75% alcohol and 90 parts of an appropriate amount of water;

[0048] (2) Hydroxypropylmethylcellulose formulated mass fraction of 13% aqueous solution; the preparation, in water with stirring first heated up to 70 deg.] C was added in batches hydroxypropyl methylcellulose powder dissolved completed after cooling in an ice bath;

[0049] (3) chitosan hydrochloride formulated mass fraction of 8% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 50 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydrochloride;

[0050] (4) immersed in the heavy floor powder 90g volume concentration of 75% ethanol was stirred with a magnetic stirrer for 50 hours, filtered and the filtrate obtained residue was discarded, and the filtrate extract heavy floor;

[0051] (5) Weigh 22g of polyvinylpyrrolidone, and then were added 13% aqueous solution of the hydroxypropyl methylcellulose, 8% aqueous solution of hydrochloric acid, chitosan, Paridis extract, then add glycerol, povidone-iodine solution, stirred until dissolved, after degassing to obtain the pharmaceutical composition.

Example Embodiment

[0052] Example 2

[0053] Starting material: hydroxypropyl methyl cellulose 15g, polyvinylpyrrolidone 25g, glycerin 30g, iodine solution 25g, 5g chitosan hydrochloride and re-building extract 4g.

[0054] It was prepared by the following method:

[0055] (1) ready hydroxypropylmethylcellulose 15g, glycerin 30g, iodine solution 25g, 5g chitosan hydrochloride and re-building 4g, 75% ethanol and the amount of water 100g;

[0056] (2) Hydroxypropylmethylcellulose formulated mass fraction of 15% aqueous solution; preparing, under agitation after the first water heated to 80 deg.] C was added in batches hydroxypropyl methylcellulose powder dissolved completed after cooling in an ice bath;

[0057] (3) chitosan hydrochloride formulated mass fraction of 10% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 75 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydrochloride;

[0058] (4) The weight of the powder was immersed in F 100g volume concentration of 75% ethanol was stirred with a magnetic stirrer for 75 hours and filtered to obtain filtrate residue was discarded, and the filtrate extract heavy floor;

[0059] (5) Weigh 25g of polyvinylpyrrolidone, and then were added 15% aqueous solution of the hydroxypropyl methylcellulose, chitosan 10% aqueous hydrochloric acid, extract heavy floor, then add glycerol, povidone-iodine solution, stirred until dissolved, after degassing to obtain the pharmaceutical composition.

Example Embodiment

[0060] Example 3

[0061] Starting material: hydroxypropyl methyl cellulose 16g, polyvinylpyrrolidone 28g, glycerin 32g, iodine solution 27g, chitosan hydrochloride and re-building 6g 5g.

[0062] It was prepared by the following method:

[0063] (1) ready hydroxypropylmethylcellulose 16g, glycerin 32g, iodine solution 27g, chitosan hydrochloride and re-building 6g 5g, 75% ethanol and the amount of water 120g;

[0064] (2) Hydroxypropylmethylcellulose formulated mass fraction of 16% aqueous solution; the preparation under stirring into the first water heated at 90 ℃ for batches hydroxypropyl methyl cellulose powder was added, complete dissolution after cooling in an ice bath;

[0065] (3) chitosan hydrochloride formulated mass fraction of 12% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 90 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydrochloride;

[0066] (4) The weight of the powder was immersed in F 120g volume concentration of 75% ethanol was stirred with a magnetic stirrer for 90 hours, filtered and the filtrate obtained residue was discarded, and the filtrate extract heavy floor;

[0067] (5) Weigh 28g of polyvinylpyrrolidone, and then were added 16% aqueous solution of the hydroxypropyl methylcellulose, chitosan aqueous solution of 12% hydrochloric acid, extract heavy floor, then add glycerol, povidone-iodine solution, stirred until dissolved, after degassing to obtain the pharmaceutical composition.

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Description & Claims & Application Information

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the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine

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Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products

ActiveCN113230163APromote blood circulationPromote hair growthCosmetic preparationsHair cosmeticsChicory root extractGrowth cycle

Owner:宁波见睿新材料有限公司

Active agent for repairing hair follicles and dredging meridians and collaterals

PendingCN114392223ARepair hair folliclesPromote growthCosmetic preparationsHair cosmeticsActive agentSurface-active agents

Owner:吉林省李婧健康产业有限公司

Classification and recommendation of technical efficacy words

Promote hair growth
Repair hair follicles

Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

A technology for hair growth and skin trauma, applied in drug combination, skin diseases, drug delivery, etc., can solve the problems of wound healing speed, lack of formula, etc., achieve shortened film forming time, good integrity, and promote hair growth Effect

AI-Extracted Technical Summary

Problems solved by technology

Method used

Abstract

Image

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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