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Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

A technology for hair growth and skin trauma, applied in drug combination, skin diseases, drug delivery, etc., can solve the problems of wound healing speed, lack of formula, etc., achieve shortened film forming time, good integrity, and promote hair growth Effect

Active Publication Date: 2021-10-15
GUANGXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the preparation makes the treatment of the wound more convenient and prevents infection than the existing wound healing medicine, it lacks in-depth research and improvement on the formula, and the speed of promoting wound healing still needs to be improved

Method used

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  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof
  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof
  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Raw materials: 12g of hydroxypropyl methylcellulose, 22g of polyvinylpyrrolidone, 26g of glycerol, 22g of povidone iodine solution, 3g of chitosan hydrochloride and 3g of polyphyll.

[0046] Prepared as follows:

[0047] (1) Prepare 12g of hydroxypropyl methylcellulose, 26g of glycerol, 22g of iodophor solution, 3g of chitosan hydrochloride and 3g of papaya, 90 parts of 75% alcohol and an appropriate amount of water;

[0048] (2) Hydroxypropyl methylcellulose is formulated into an aqueous solution with a mass fraction of 13%; during preparation, the water is warmed up to 70°C under stirring, and then hydroxypropyl methylcellulose powder is added in batches, and the dissolution is complete Cool down in an ice bath;

[0049] (3) Chitosan hydrochloride is formulated into an aqueous solution with a mass fraction of 8%. When dissolving, after the chitosan hydrochloride powder is dissolved in water, stir and dissolve in a hot water bath at 50°C. After dissolving, Ultrasonic...

Embodiment 2

[0053] Raw materials: 15g of hydroxypropyl methylcellulose, 25g of polyvinylpyrrolidone, 30g of glycerol, 25g of povidone iodine solution, 5g of chitosan hydrochloride and 4g of Chonglou extract.

[0054] Prepared as follows:

[0055] (1) Prepare 15g of hydroxypropyl methylcellulose, 30g of glycerol, 25g of iodophor solution, 5g of chitosan hydrochloride and 4g of papaya, 100g of 75% alcohol and an appropriate amount of water;

[0056] (2) Hydroxypropyl methylcellulose is formulated into an aqueous solution with a mass fraction of 15%; during preparation, the water is warmed up to 80°C under stirring, and then hydroxypropyl methylcellulose powder is added in batches, and the dissolution is complete Cool down in an ice bath;

[0057] (3) Chitosan hydrochloride is formulated into an aqueous solution with a mass fraction of 10%. When dissolving, after the chitosan hydrochloride powder is dissolved in water, stir and dissolve in a hot water bath at 75°C. After dissolving, Ultras...

Embodiment 3

[0061] Raw materials: 16g of hydroxypropyl methylcellulose, 28g of polyvinylpyrrolidone, 32g of glycerol, 27g of povidone iodine solution, 6g of chitosan hydrochloride and 5g of papaya.

[0062] Prepared as follows:

[0063] (1) Prepare 16g of hydroxypropyl methylcellulose, 32g of glycerol, 27g of iodophor solution, 6g of chitosan hydrochloride and 5g of papaya, 120g of 75% alcohol and an appropriate amount of water;

[0064] (2) Hydroxypropyl methylcellulose is formulated into an aqueous solution with a mass fraction of 16%; during preparation, the water is warmed up to 90°C under stirring, and then hydroxypropyl methylcellulose powder is added in batches, and the dissolution is complete Cool down in an ice bath;

[0065] (3) Chitosan hydrochloride is formulated into an aqueous solution with a mass fraction of 12%. When dissolving, after the chitosan hydrochloride powder is dissolved in water, stir and dissolve in a hot water bath at 90°C. After dissolving, Ultrasonic degas...

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Abstract

The invention provides a combined medicine for promoting skin wound healing and hair growth and a preparation method thereof, belonging to the technical field of wound treatment. The drug is mainly prepared from the following raw materials in parts by weight: 12-16 parts of hydroxypropyl methylcellulose, 22-28 parts of polyvinylpyrrolidone, 26-32 parts of glycerol, 22-27 parts of iodophor solution, shell Polysaccharide hydrochloride 3-6 parts and Chonglou 3-5 parts. The preparation method is to weigh polyvinylpyrrolidone, add 13-16% aqueous solution of hydroxypropyl methylcellulose, 8-12% aqueous solution of chitosan hydrochloric acid, and the extract of S. chinensis, then add glycerol and iodophor, and stir After dissolving and degassing, the combined medicine is obtained. The drug forms a dense protective film on the wound to protect the secondary injury of the wound and sterilizes and reduces inflammation through traditional Chinese medicine. At the same time, it promotes wound healing through polymer materials, can shorten the time of wound healing, and has the function of promoting hair growth. .

Description

【Technical field】 [0001] The invention relates to the technical field of wound treatment, in particular to a combined medicine for promoting skin wound healing and hair growth and a preparation method thereof. 【Background technique】 [0002] Cutaneous trauma is the loss of epidermal tissue of the skin, which is a common and frequently-occurring disease, such as cuts, abrasions, surgical incisions, diabetic trauma, radiotherapy and chemotherapy wounds, skin ulcers, burns, post-transplant trauma, trauma caused by vascular diseases, bedsores , frostbite, wounds after mosquito bites, etc. Skin wounds are divided into different types. The mildest wounds are limited to the epidermal layer of the skin and those with severe skin and subcutaneous tissue fractures, and those with severe wounds include ruptures and fractures of muscles, muscle tendons, and nerves. Wounds limited to the surface of the skin are healed through epithelial regeneration, while the latter two often require m...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/08A61K47/32A61K47/36A61K47/38A61P7/04A61P17/02A61P29/00A61P31/02A61P31/04A61K33/18A61K31/722
Inventor 陈明刘虎宸李亚萍杨桦许少华舒伟
Owner GUANGXI NORMAL UNIV
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