Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

A technology for hair growth and skin trauma, applied in drug combination, skin diseases, drug delivery, etc., can solve the problems of wound healing speed, lack of formula, etc., achieve shortened film forming time, good integrity, and promote hair growth Effect

Active Publication Date: 2021-10-15
GUANGXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the preparation makes the treatment of the wound more convenient and prevents infection than the existing wound healing med

Method used

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  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof
  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof
  • Combination medicine for promoting skin wound healing and hair growth and preparation method thereof

Examples

Experimental program
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Effect test

Example Embodiment

[0044] Example 1

[0045] Starting material: hydroxypropyl methyl cellulose 12g, polyvinylpyrrolidone 22g, glycerin 26g, iodine solution 22g, chitosan hydrochloride and re-building 3g 3g.

[0046] It was prepared by the following method:

[0047] (1) ready hydroxypropylmethylcellulose 12g, glycerin 26g, iodine solution 22g, chitosan hydrochloride and re-building 3g 3g, 75% alcohol and 90 parts of an appropriate amount of water;

[0048] (2) Hydroxypropylmethylcellulose formulated mass fraction of 13% aqueous solution; the preparation, in water with stirring first heated up to 70 deg.] C was added in batches hydroxypropyl methylcellulose powder dissolved completed after cooling in an ice bath;

[0049] (3) chitosan hydrochloride formulated mass fraction of 8% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 50 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydroc...

Example Embodiment

[0052] Example 2

[0053] Starting material: hydroxypropyl methyl cellulose 15g, polyvinylpyrrolidone 25g, glycerin 30g, iodine solution 25g, 5g chitosan hydrochloride and re-building extract 4g.

[0054] It was prepared by the following method:

[0055] (1) ready hydroxypropylmethylcellulose 15g, glycerin 30g, iodine solution 25g, 5g chitosan hydrochloride and re-building 4g, 75% ethanol and the amount of water 100g;

[0056] (2) Hydroxypropylmethylcellulose formulated mass fraction of 15% aqueous solution; preparing, under agitation after the first water heated to 80 deg.] C was added in batches hydroxypropyl methylcellulose powder dissolved completed after cooling in an ice bath;

[0057] (3) chitosan hydrochloride formulated mass fraction of 10% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 75 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydrochloride; ...

Example Embodiment

[0060] Example 3

[0061] Starting material: hydroxypropyl methyl cellulose 16g, polyvinylpyrrolidone 28g, glycerin 32g, iodine solution 27g, chitosan hydrochloride and re-building 6g 5g.

[0062] It was prepared by the following method:

[0063] (1) ready hydroxypropylmethylcellulose 16g, glycerin 32g, iodine solution 27g, chitosan hydrochloride and re-building 6g 5g, 75% ethanol and the amount of water 120g;

[0064] (2) Hydroxypropylmethylcellulose formulated mass fraction of 16% aqueous solution; the preparation under stirring into the first water heated at 90 ℃ for batches hydroxypropyl methyl cellulose powder was added, complete dissolution after cooling in an ice bath;

[0065] (3) chitosan hydrochloride formulated mass fraction of 12% aqueous solution, when dissolved, dissolved in water, stirred and dissolved at 90 deg.] C in a hot water bath chitosan hydrochloride powder dissolved after ultrasonic degassing, to obtain an aqueous solution of chitosan hydrochloride;

[0066...

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Abstract

The invention provides a combined medicine for promoting skin wound healing and hair growth and a preparation method thereof, belonging to the technical field of wound treatment. The drug is mainly prepared from the following raw materials in parts by weight: 12-16 parts of hydroxypropyl methylcellulose, 22-28 parts of polyvinylpyrrolidone, 26-32 parts of glycerol, 22-27 parts of iodophor solution, shell Polysaccharide hydrochloride 3-6 parts and Chonglou 3-5 parts. The preparation method is to weigh polyvinylpyrrolidone, add 13-16% aqueous solution of hydroxypropyl methylcellulose, 8-12% aqueous solution of chitosan hydrochloric acid, and the extract of S. chinensis, then add glycerol and iodophor, and stir After dissolving and degassing, the combined medicine is obtained. The drug forms a dense protective film on the wound to protect the secondary injury of the wound and sterilizes and reduces inflammation through traditional Chinese medicine. At the same time, it promotes wound healing through polymer materials, can shorten the time of wound healing, and has the function of promoting hair growth. .

Description

【Technical field】 [0001] The invention relates to the technical field of wound treatment, in particular to a combined medicine for promoting skin wound healing and hair growth and a preparation method thereof. 【Background technique】 [0002] Cutaneous trauma is the loss of epidermal tissue of the skin, which is a common and frequently-occurring disease, such as cuts, abrasions, surgical incisions, diabetic trauma, radiotherapy and chemotherapy wounds, skin ulcers, burns, post-transplant trauma, trauma caused by vascular diseases, bedsores , frostbite, wounds after mosquito bites, etc. Skin wounds are divided into different types. The mildest wounds are limited to the epidermal layer of the skin and those with severe skin and subcutaneous tissue fractures, and those with severe wounds include ruptures and fractures of muscles, muscle tendons, and nerves. Wounds limited to the surface of the skin are healed through epithelial regeneration, while the latter two often require m...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/08A61K47/32A61K47/36A61K47/38A61P7/04A61P17/02A61P29/00A61P31/02A61P31/04A61K33/18A61K31/722
Inventor 陈明刘虎宸李亚萍杨桦许少华舒伟
Owner GUANGXI NORMAL UNIV
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