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Peptide composition with skin aging delaying effect as well as preparation method and application of peptide composition

A skin aging and composition technology, which is applied in the field of peptide composition and its preparation, can solve the problems of difficult anti-aging cosmetics to be added in large quantities, anti-aging products that cannot be mass-produced, and expensive, etc., to enhance cell renewal and increase skin Smoothness, low cost effect

Inactive Publication Date: 2019-06-11
SHANGHAI JAKA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Peptide ingredients are very sensitive to acid, alkali, cold, heat, and enzymes. They are usually unstable and need to be stored at low temperature, making it difficult to add a large amount in anti-aging cosmetics
In addition, in the production process, the peptide components are easily affected by the environment and lose their activity due to adverse phenomena such as color changes or precipitation. Therefore, the production equipment and production conditions such as acid, alkali, cold, heat, and enzymes are very harsh. As a result, anti-aging products containing peptides cannot be mass-produced, which leads to high prices to a certain extent

Method used

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  • Peptide composition with skin aging delaying effect as well as preparation method and application of peptide composition
  • Peptide composition with skin aging delaying effect as well as preparation method and application of peptide composition
  • Peptide composition with skin aging delaying effect as well as preparation method and application of peptide composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] (1) Measure 20wt% of 1,2-hexanediol and 80wt% of water, mix them evenly, and configure a compound solubilizer;

[0040] (2) Based on the total mass of the peptide composition, 0.01wt% palmitoyl tripeptide was dissolved with 60wt% compound solubilizer into a clear and transparent solution to obtain a small molecule oligopeptide solution;

[0041] (3) dissolving 0.3wt% silk protein peptide in water at a temperature of 40°C to obtain a macromolecular natural polypeptide aqueous solution;

[0042](4) After mixing the small molecular oligopeptide solution and the macromolecular natural polypeptide aqueous solution evenly, add 0.1wt% ethylhexylglycerin, the balance is water, and mix evenly to obtain a clear and transparent peptide combination with the effect of delaying skin aging things.

Embodiment 2

[0044] (1) Measure 20wt% of 1,2-hexanediol, 20wt% of glycerin, 10wt% of TW-20 and 50wt% of water, mix them evenly, and configure a compound solubilizer;

[0045] (2) Based on the total mass of the peptide composition, 0.01wt% of palmitoyl tripeptide and 0.1wt% of palmitoyl tetrapeptide were dissolved into a clear and transparent solution with 50wt% compound solubilizer to obtain a small molecule oligopeptide solution;

[0046] (3) Dissolving 2.5wt% silk protein peptide and 2.5wt% hydrolyzed fish collagen peptide in water at a temperature of 60°C to obtain a macromolecular natural polypeptide aqueous solution;

[0047] (4) After mixing the small molecule oligopeptide solution and the macromolecular natural polypeptide aqueous solution evenly, add 0.2wt% phenoxyethanol and 0.3wt% ethylhexylglycerin, the balance is water, and mix evenly to obtain clear and transparent A peptide composition with the effect of delaying skin aging.

Embodiment 3

[0049] (1) Measure 15wt% of 1,3-butanediol, 20wt% of 1,2 propanediol, 5wt% of RH-40, 2wt% of TW-20 and 58wt% of water, mix them evenly, and configure the compound booster solvent;

[0050] (2) Based on the total mass of the peptide composition, 0.5wt% palmitoyl hexapeptide is dissolved into a clear and transparent solution with 10-60wt% compound solubilizer to obtain a small molecule oligopeptide solution;

[0051] (3) dissolving 5wt% hydrolyzed fish collagen peptide in water at a temperature of 45°C to obtain a macromolecular natural polypeptide aqueous solution;

[0052] (4) After mixing the small molecular oligopeptide solution and the macromolecular natural polypeptide aqueous solution evenly, add 0.4wt% phenoxyethanol, the balance is water, and mix evenly to obtain a clear and transparent peptide composition with the effect of delaying skin aging .

[0053] The clear and transparent peptide composition with the effect of delaying skin aging (hereinafter referred to as t...

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Abstract

The invention relates to the technical field of cosmetics, and in particular relates to a peptide composition with a skin aging delaying effect and a preparation method and application thereof. The peptide composition with the skin aging delaying effect is prepared from the following components in percentage by mass: 0.3 to 5 percent of macromolecular natural polypeptide, 0.01 to 0.5 percent of small molecular oligopeptide, 10 to 60 percent of compound solubilizer, 0.1 to 0.5 percent of preservative and the balance of water. The peptide composition with the skin aging delaying effect is good in stability, the skin surface layer cell renewal effect can be enhanced, and the effects of relieving wrinkles and improving the skin smoothness are achieved; the preparation method is simple to operate, has no special requirements on equipment and is convenient for realizing industrialization; and the peptide composition is a transparent solution, the composition can be conveniently applied to any dosage form such as cream, emulsion, toning lotion, gel and facial mask, so that the use convenience is improved, and the composition has a wide application prospect.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a peptide composition with the effect of delaying skin aging and its preparation method and application. Background technique [0002] With the improvement of life quality, more and more people pay attention to skin care. How to reduce wrinkles, restore youthful complexion, and delay skin aging is a challenging problem in skin care and an enduring research in the field of cosmetics. topic. Skin aging, that is, skin aging, refers to the aging damage of skin function, which makes the skin's ability to protect the body and adjustment ability decline, so that the skin cannot adapt to changes in the internal and external environment, and the overall appearance of color, luster, shape, texture, etc. appears. change. Skin aging can be manifested as the slowing down of the proliferation of keratinocytes in the epidermis, the flattening of the junction between the dermis and the loss ...

Claims

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Application Information

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IPC IPC(8): A61K8/65A61K8/64A61K8/34A61K8/92A61K8/49A61Q19/08
Inventor 杨雅迪周春霞谢红卢伊娜
Owner SHANGHAI JAKA BIOTECH CO LTD
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