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Medicine for treating yellow shoot disease to bear good fruits and preparation method and use method thereof

A medicine and the technology of Huanglong are applied in the field of medicines for treating Huanglongbing with good results and the preparation field thereof, which can solve the problems of not fundamentally eliminating Huanglongbing bacteria, only digging or cutting down diseased trees, etc., so as to avoid major economic losses. , inhibiting or killing gram-negative bacteria

Pending Publication Date: 2019-07-02
谢宏华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the prevention and control methods for this disease mainly include two aspects: one is to focus on prevention, check the seedlings, strengthen the management of seedling breeding, eliminate diseased seedlings in time, and select disease-free seedlings for planting and scion; and biological methods to prevent and control psyllids, mainly using insecticides, acaricides, clearing gardens in winter, building windbreaks, cutting off the transmission route of pathogens, and controlling the spread and spread of Huanglongbing; on the other hand, for slightly infected For diseased trees and orchards with small infected areas, timely cut off diseased branches and strengthen cultivation management, mainly including reasonable fertilization and irrigation, removal of summer shoots, cutting off elongated branches, and appropriate fruit thinning; When it exceeds 60%, people can only dig up or cut down the diseased tree; although the above several control methods have controlled the reproduction of Huanglongbing bacteria on citrus to a certain extent, and reduced the harm of Huanglongbing to citrus, they have not Fundamentally Eliminate Huanglongbing Bacteria in Citrus
Chemotherapy is considered to be a very effective means of preventing and treating citrus huanglongbing. However, because the pathogen resides in the phloem of citrus, especially the thick wax layer on the epidermis of citrus leaves, it restricts the effective drug transport through the leaf epidermis to the phloem.

Method used

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  • Medicine for treating yellow shoot disease to bear good fruits and preparation method and use method thereof
  • Medicine for treating yellow shoot disease to bear good fruits and preparation method and use method thereof
  • Medicine for treating yellow shoot disease to bear good fruits and preparation method and use method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0047]In this example, ampicillin was used as the β-lactam antibiotic, sulbactam was used as the β-lactamase inhibitor, starch was used as the filler, starch carboxymethyl sodium was used as the disintegrant, and magnesium stearate was used as the lubricant. Fatty acid adopts stearic acid and palmitic acid; The weight ratio of sulbactam and ampicillin is 1 / 3~2 / 3; Figure 5 , Figure 6 and Figure 7 Shown, the medicine of this embodiment one comprises 54%~57% ampicillin, 26%~29% sulbactam, 10.1%~18.4% starch, 1.2%~4.5% carboxymethyl starch sodium, 0.6% ~1.9% magnesium stearate, 0.04%~0.08% stearic acid, 0.02%~0.04% palmitic acid and 0.04%~0.08% simethicone; The bacterial cell wall of gram-negative bacteria is defective, and the bacterium swells and cracks, so it can not only inhibit its proliferation, but also directly kill bacteria that penetrate gram-negative bacteria, but it is easy to be β-lactam produced by gram-negative bacteria Enzyme decomposition, therefore, combine...

Embodiment 2

[0059] The medicine of this embodiment two comprises 55% ampicillin, 27% sulbactam, 14.2% starch, 2.6% carboxymethyl starch sodium, 1.1% magnesium stearate, 0.04% stearic acid, 0.02% palmitic acid by weight percentage and 0.04% simethicone; in embodiment two, the combination of 55% ampicillin and 27% sulbactam can make Gram-negative bacteria be penetrated and killed and ampicillin will not be destroyed by β-lactamase 14.2% starch neutralizes 55% ampicillin with better drug properties, 1.1% magnesium stearate, 0.04% stearic acid, and 0.02% palmitic acid combine to make stearin Magnesium acid promotes the rapid diffusion of ampicillin in the phloem of the fruit tree with Huanglong disease, so that it can quickly enter the circulatory system, transport the drug to various parts such as flowers, leaves, branches, etc., and comprehensively kill the pathogens in each part of the diseased tree, so that the disease of flowers and leaves The tree gradually turns green to normal leaves....

Embodiment 3

[0074] The medicine of this embodiment three comprises 56% ampicillin, 28% sulbactam, 12.5% ​​starch, 1.8% sodium starch glycolate, 1.5% magnesium stearate, 0.08% stearic acid, 0.04% palmitic acid by weight percentage and 0.08% simethicone; in embodiment three, the combination of 56% ampicillin and 28% sulbactam can make Gram-negative bacteria be penetrated and killed and ampicillin will not be destroyed by β-lactamase Decomposition, so that the effect on Gram-negative bacteria is better, 12.5% ​​starch neutralizes 56% ampicillin, the drug properties are better, carboxymethyl starch sodium makes ampicillin more easily absorbed into the phloem; 1.5% magnesium stearate, 0.08% The combination of stearic acid and 0.04% palmitic acid can make magnesium stearate promote the rapid diffusion of ampicillin in the phloem of Huanglongbing fruit tree, so that it can quickly enter the circulatory system and transport the drug to various parts such as flowers, leaves, branches, etc. Kill th...

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Abstract

The invention relates to the technical field of fruit tree disease treatment, in particular to a medicine for treating the yellow shoot disease to bear good fruits and a preparation method and use method thereof. The medicine comprises in percent by weight: 80%-86% of a component 1 and 12%-25% of a component 2; the component 1 comprises a beta-lactam antibiotic used for resisting gram negative bacteria; and the component 2 comprises a filler. According to the medicine for treating the yellow shoot disease to bear good fruits, the beta-lactam antibiotic penetrates through gram negative bacteriato inhibit the proliferation of the bacteria, so that the phloem inside the yellow shoot disease fruit trees is inhibited and killed, the sieve tube cells of the fruit trees are unblocked, and the nutrients and water of fruit trees can be normally supplied to the branches to bear good fruits. The medicine for treating the yellow shoot disease to bear good fruits has good effects on yellow shoot disease fruit trees, gram negative bacteria can be effectively inhibited and killed, and thus trees infected with the yellow shoot disease can be treated, the trees can bear good fruits, and major economic losses caused by digging or cutting down the disease trees are avoided.

Description

technical field [0001] The invention relates to the technical field of fruit tree disease treatment, in particular to a medicine for treating Huanglong disease with good fruit and its preparation method and application method. Background technique [0002] Huanglongbing, also known as yellow shoot disease, yellow wilt, green fruit disease, is an important disease in the production of citrus and navel oranges, and is subject to international and domestic quarantine. 11 of the 17 citrus producing areas in China have received the threat of Huanglongbing disease , and Jiangxi, Guangdong, Guangxi, Fujian, Yunnan, Hainan and other places, which are the main producing areas of citrus, are particularly serious. Typical symptoms of diseased citrus plants are "yellow shoots", mottled yellowing of leaves, smaller fruit, formation of worthless "green fruit" or "red nose fruit", root necrosis in the later stage of disease, tree vigor decline, resulting in leaf drop, fruit drop, plant De...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/12A01N43/90A01P1/00
CPCA01N25/12A01N43/90
Inventor 谢宏华
Owner 谢宏华
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