Compound preparation for relieving alcoholism and protecting liver and application thereof

Abstract

The invention discloses preparation and an application of a compound extract for relieving alcoholism and protecting liver. The compound extract is composed of radix puerariae, green olive, semen hoveniae, dendrobium officinale and an ampelopsis grossedentata extract of ampelopsis grossedentata as the main traditional Chinese medicine components. According to the theory of traditional Chinese medicine in China and the basic principle of medication for treatment, a formula of the compound extract for relieving alcoholism and protecting liver is provided by screening for symptomatic and verifiable effects in abundant traditional Chinese medicine; for the first time, radix puerariae, semen hoveniae and ampelopsis grossedentata are combined, and the composition of the formula for relieving alcoholism and protecting liver is optimized. Through the result of determination and screening of the enzyme activation activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in vitroby each extract, the formula of the compound extract for relieving alcoholism and protecting liver is determined, and the optimum proportion of the formula is ensured; the compound extract is mixed with medicinal excipients to prepare oral preparations which can be either hard capsules, soft capsules, tablets, granules, powder, pills, tea bags, soft sugar, oral liquids or beverages, and is easy to use.

Description

technical field [0001] The invention relates to a compound preparation for relieving alcohol and protecting the liver and its application. Background technique [0002] Alcohol is the most commonly used drug in the world, and it is also a liver poison that is widely accepted by society; China's wine culture has a long history, and wine has a history of more than 8,000 years from its invention to today. People have a love-hate relationship with alcohol; a small amount of drinking can activate blood, dredge collaterals and dispel cold, regulate mood, and eliminate fatigue and tension; while uncontrolled drinking can cause many diseases including cardiovascular system, nervous system and digestive system. Tissue and organ damage. "Compendium of Materia Medica" says: "If you drink too much, you will kill instantly"; surveys show that among patients who drink alcohol for a long time, about 57.5% of the patients have fatty liver and 15% of the patients have liver cirrhosis; some ...

AI Technical Summary

Problems solved by technology

"Compendium of Materia Medica" said: "Drinking without temperance, killing people in an instant"; surveys show that among patients who drink alcohol for a long time, about 57.5% of patients have fatty liver, and 15% of patients have liver cirrhosis; some digestive system tumors such as gastric cancer , esophageal cancer, and liver cancer are also closely related to alcoholism; alcoholism has become an increasingly serious threat to people's health; The demand for products is very important and urgent. Some of the existing anti-alcohol formulas use Pueraria lobata root and Hovenia dulcis as the main functional ingredients. For example, Patent No. 101658648B discloses a compound preparation and application of anti-alcoholism and liver protection. , Hovenia dulcis is the main functional ingredient, and it is not combined with Mao Yanberry. In the prior art, the anti-alcoholic and liver-protecting formula is determined first, and then the activity is tested, so the determined formula is not necessarily the best for anti-alcoholic and liver-protecting activities.

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