Method for assessing health status of mammary gland and quality of breast milk through detecting flora composition of mammary gland or milk samples, and application of method
A technology of health status and flora, applied in the fields of bioinformatics and medical health, to assess and improve the quality of breast milk
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[0012] Embodiment: A method and its application for detecting the composition of mammary gland or milk sample flora to assess the health status of mammary gland and breast milk quality
[0013] The theoretical basis of the present invention is based on the reanalysis of the 16SrRNA data of human milk microflora first published by Hunt et al. in 2011. The data included 47 milk samples, and after sequencing and subsequent bioinformatics analysis, 15 were highly enriched in milk samples, including Staphylococcus and Corynebacterium.
[0014] Based on the relative abundance of each genera in the breast milk flora, the interaction relationship between 15 genera was obtained by the Spearman rank correlation method, and the interaction relationship with p value less than or equal to 0.05 was selected for complex network analysis. Using Cytoscape 2.8.3, the bacterial genera were used as network nodes, and the interaction relationship between bacterial genera was used as edges to const...
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